Description
Dr. Mario Mauthe is a senior scientist at the Department of Biomedical Sciences of Cells and Systems at the University Medical Center in Groningen, the Netherlands. His research focus lies in the mechanism and regulation of autophagy under physiological and pathological conditions. He is specifically interested in the relevance of autophagy in neurodegenerative diseases. He obtained his PhD at the University of Tuebingen, Germany on studying the role of WIPI1 and WIPI2 in the regulation of autophagy. Afterwards he joined the laboratory of Prof. Reggiori in the Netherlands. His research now focuses on understanding the contribution of autophagy, in particular the WIPI proteins, in specific pathologies. Because WDR45/WIPI4 belongs to the WIPI protein family and is associated with BPAN, he is now focusing his research on this disease to exploit autophagy as a potential treatment venue for BPAN. Furthermore, he is studying at the molecular level how autophagy, and more specifically a selective type of autophagy called aggrephagy, contributes to the clearance of protein aggregates, a hallmark of numerous neurodegenerative disorders.| Period | 17-May-2024 |
|---|---|
| Event title | BPAN Disease Symposium |
| Event type | Symposium |
| Location | Bordeaux, FranceShow on map |
| Degree of Recognition | International |