Antiviral immune response linked to depression in mice

Press/Media: ResearchAcademic

Description

The flu and other viral infections have long been known to cause mood changes, beyond the more familiar symptoms of fever and sore throat. A study in mice, published April 19, 2016 in Immunity, now reveals how the antiviral immune response alters brain activity. Upon infection, brain cells lining blood vessels produce a protein called CXCL10, which impairs neuronal firing in the hippocampus — a brain region important in learning, memory, and mood.

Period19-Apr-2016

Media coverage

1

Media coverage

  • TitleAntiviral immune response linked to depression in mice
    Degree of recognitionInternational
    Media name/outletNeuroscience News
    Media typeWeb
    Country/TerritoryUnited States
    Date19/04/2016
    DescriptionThe flu and other viral infections have long been known to cause mood changes, beyond the more familiar symptoms of fever and sore throat. A study in mice, published April 19, 2016 in Immunity, now reveals how the antiviral immune response alters brain activity. Upon infection, brain cells lining blood vessels produce a protein called CXCL10, which impairs neuronal firing in the hippocampus — a brain region important in learning, memory, and mood.
    Producer/AuthorJoseph Caputo
    URLneurosciencenews.com/cxcl10-antiviral-hippocampus-depression-4080/
    PersonsUlrich Eisel