Closing the door: Breaking new ground related to a potential anticancer drug target

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In order to sustain fast growth, cancer cells need to take up nutrients at a faster rate than healthy cells. The human glutamine transporter ASCT2 allows the amino acid glutamine to enter cells and is upregulated in many types of cancer cells, which need more glutamine. It is a potential target for new anti-cancer drugs. Researchers have now elucidated a structure of the human ASCT2 that provides unprecedented insight in the workings of this protein.
Period31-Jul-2019

Media coverage

1

Media coverage

  • TitleClosing the door: Breaking new ground related to a potential anticancer drug target
    Degree of recognitionInternational
    Media name/outletScience Daily
    Media typeWeb
    CountryNetherlands
    Date31/07/2019
    DescriptionIn order to sustain fast growth, cancer cells need to take up nutrients at a faster rate than healthy cells. The human glutamine transporter ASCT2 allows the amino acid glutamine to enter cells and is upregulated in many types of cancer cells, which need more glutamine. It is a potential target for new anti-cancer drugs. Researchers have now elucidated a structure of the human ASCT2 that provides unprecedented insight in the workings of this protein.
    URLhttps://www.sciencedaily.com/releases/2019/07/190731102142.htm
    PersonsDirk Slotboom, Cristina Batista Paulino, Albert Guskov, Alisa Garaeva