Biotechnologists used a computational method to redesign aspartase and convert it to a catalyst for asymmetric hydroamination reactions. Their colleagues in China scaled up the production of this enzyme and managed to produce kilograms of very pure building blocks for pharmaceuticals and other bioactive compounds.
Media contributions
1Media contributions
Title Computer Redesigns Enzyme Degree of recognition International Media name/outlet Findnews.uk Media type Web Date 21/05/2018 Description This post was originally published on this site .
Biotechnologists used a computational method to redesign aspartase and convert it to a catalyst for asymmetric hydroamination reactions. Their colleagues in China scaled up the production of this enzyme and managed to produce kilograms of very pure building blocks for pharmaceuticals and other bioactive compounds.URL findnews.uk/2018/05/21/computer-redesigns-enzyme/ Persons Dick Janssen, Hein Wijma
Keywords
- computational design
- enzyme engineering
- chemical building blocks
- directed evolution