Title Eighteen innovative research projects launched through Open Competition Domain Science-M programme Degree of recognition International Media name/outlet NWO - News Media type Web Country/Territory Netherlands Date 07/07/2023 Description he NWO Domain Board Science has approved eighteen grant applications in the Open Competition Domain Science-M programme. The topics vary from improvement of climate models and recycling of e-waste, to anxiety and hyperactivity in anorexia and research into dark matter. M-grants are intended for innovative, high-quality, fundamental research and/or studies involving matters of scientific urgency.
The following applications have been approved (in alphabetical order, by author):
Understanding the master chaperone of our cells
dr. Sonja Schmid & dr. Katarzyna Tych (WUR/RUG)
Proteins constitute the molecular machines in our cells. However, many of them would be non-functional without the help of the cell’s master chaperone, Hsp90, which turns them into functional entities. Surprisingly, despite this central role, we still don’t understand how this Hsp90 actually works. We will therefore use new technology to elucidate the relevant small scale of individual molecules. We will test how Hsp90 is energetically powered, how it treats the other proteins, and how it coordinates its necessary helper proteins. Our research will provide a currently missing molecular-level understanding of Hsp90 and thus inform the development of cancer therapeutics.
About the NWO Open Competition Domain Science-M
M-grants are intended for realising curiosity-driven, fundamental research of high quality and/or scientific urgency. The M-grant offers researchers the possibility to elaborate creative and risky ideas and to realise scientific innovations that can form the basis for the research themes of the future. There are three categories of M-grants: M-1 (one scientific position), M-2 (two scientific positions in collaboration) and M-invest (investments) that are assessed in competition with each other.
In this M-round (package 22-2), a total of 72 grant applications were evaluated, of which 44 M-1 proposals, 27 M-2 proposals and 1 M-invest proposal. The NWO Domain Science Board decided to award five M-2 proposals and thirteen M-1 proposals.
For more information about the Open Competition Domain Science – M, please contact Linda Jongbloed or Merijn Blaakmeer, ENW-M@nwo.nl, +31 (0) 70 349 4600 or +31 (0) 70 349 4182
Producer/Author NWO URL https://www.nwo.nl/en/news/eighteen-innovative-research-projects-launched-through-open-competition-domain-science-m-programme Persons Kasia Tych