New impetus for treatment neurodegenerative diseases

Description

Twenty years ago, tumor necrosis factor (TNF) seemed a promising target in the treatment of brain diseases like multiple sclerosis or Alzheimer's Disease. But clinical trials produced disappointing results. Now University of Groningen scientists and a group of European colleagues have made an important discovery that explains the failure of these trials, and points the way to promising new treatments. The results were published on 10 October in Proceedings of the National Academy of Sciences.