Scientists reveal structure of amino acid transporter involved in cancer

Press/Media: ResearchPopular

Description

(University of Groningen) The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses. A team of University of Groningen scientists have used cryo-electron microscopy to elucidate the structure of the protein, which may generate leads for drug development. The results were published in Nature Structural & Molecular Biology on 5 June.

Period4-Jun-2018

Media coverage

1

Media coverage

  • TitleScientists reveal structure of amino acid transporter involved in cancer
    Degree of recognitionInternational
    Media name/outletBioPortfolio - Biotech, Healthcare and Medical Resources
    Media typeWeb
    CountryNetherlands
    Date04/06/2018
    Description(University of Groningen) The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses. A team of University of Groningen scientists have used cryo-electron microscopy to elucidate the structure of the protein, which may generate leads for drug development. The results were published in Nature Structural & Molecular Biology on 5 June.
    Producer/AuthorBioPortfolio
    URLhttps://www.bioportfolio.com/news/article/3649331/Scientists-reveal-structure-of-amino-acid-transporter-involved-in-cancer.html
    PersonsCristina Batista Paulino, Albert Guskov, Dirk Slotboom, Alisa Garaeva, Gerrit Oostergetel

Keywords

  • protein structure
  • amino acid transporter
  • cryo-EM
  • cancer