Additional file 7 of Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia

  • Suzanne S. M. Miedema (Contributor)
  • Christine de Veij Mestdagh (Contributor)
  • Kevin Menden (Contributor)
  • Ka Wan Li (Contributor)
  • Henne Holstege (Contributor)
  • Iryna Paliukhovich (Contributor)
  • Patrizia Rizzu (Contributor)
  • David C. Hondius (Contributor)
  • Frank T.W. Koopmans (Contributor)
  • van Rooij (Contributor)
  • Merel O Mol (Contributor)
  • Shamiram Melhem (Contributor)
  • John C. van Swieten (Contributor)
  • Pim van Nierop (Contributor)
  • Andrea B. Ganz (Contributor)
  • Ronald E. van Kesteren (Contributor)
  • Peter Heutink (Contributor)
  • August B. Smit (Contributor)

    Dataset

    Description

    Additional file 7 Lists of SynGO enrichment analysis results for proteins differentially expressed in frontal cortical FTD-GRN vs NDC and temporal cortical FTD-MAPT vs NDC. SynGO enrichment analysis was performed on proteins differentially expressed at q < 0.05, with proteins divided into lower and higher expressed proteins. For every SynGO term, the proteins within that term that were measured in the different FTD subtypes are given, as well the raw and multiple testing corrected p-value for the enrichment analysis.
    Date made available7-Jul-2022
    Publisherfigshare Academic Research System

    Keywords on Datasets

    • Frontotemporal dementia
    • GRN
    • MAPT
    • Human brain proteomics
    • Cell type enrichment

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