We aimed to evaluate the association between statin use and cognitive function. Cognitive function was measured with the Ruff Figural Fluency Test (RFFT; worst score, 0; best score, 175 points) and the Visual Association Test (VAT; low performance, 0-10; high performance, 11-12 points) in an observational study that included 4,095 community-dwelling participants aged 35-82 years. Data on statin use were obtained from a computerized pharmacy database. Analysis were done for the total cohort and subsamples matched on cardiovascular risk (N=1232) or propensity score for statin use (N=3609). We found that a total of 904 participants (10%) used a statin. Statin users were older than non-users: mean age (SD) 61 (10) vs. 52 (11) years
Date made available | 3-Jan-2015 |
---|
Publisher | University of Groningen |
---|
Geographical coverage | City of Groningen, The Netherlands |
---|
- Medical sciences
- Cognition
- cognitive functions
- cohort
- Fluency
- prospective study
- Statin
- HMG-CoA reductase inhibitors