Research output per year
Research output per year
Personal profile
Research interests
My research interest focuses on the research of molecular mechanisms underlying cerebrovascular diseases, aging processes, and neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. I investigated the role of statins and various natural products, including linalool, as potential neuroprotective agents in neurodegenerative diseases. Lately, my focus has shifted towards delving into mitochondrial metabolism and its link to inflammation in the context of neurodegenerative diseases, particularly the generation and characterization of human microglia derived from induced pluripotent stem cells of Parkinson's disease patients. I am greatly interested in expanding my research in understanding neuroinflammation as a key factor in neurodegenerative diseases.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mitochondrial transplantation rescues neuronal cells from ferroptosis
Chen, T., Majerníková, N., Marmolejo-Garza, A., Trombetta-Lima, M., Sabogal-Guáqueta, A. M., Zhang, Y., Ten Kate, R., Zuidema, M., Mulder, P. P. M. F. A., den Dunnen, W., Gosens, R., Verpoorte, E., Culmsee, C., Eisel, U. L. M. & Dolga, A. M., 1-Nov-2023, In: Free Radical Biology and Medicine. 208, p. 62-72 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile15 Downloads (Pure) -
The importance of microglia in metabolic changes in the brain: A world to explore
Sabogal Guaqueta, A., 2023.Research output: Contribution to conference › Poster › Academic
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Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies
Goldsteen, P., Sabogal Guaqueta, A., Mulder, P., Bos, I. S. T., Eggens, M., van der Koog, L., Soeiro, J. T., Halayko, A. J., Mathwig, K., Kistemaker, L., Verpoorte, E., Dolga, A. & Gosens, R., 28-Oct-2022, In: Frontiers in Pharmacology. 13, 16 p., 991072.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)68 Downloads (Pure) -
Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity
Musheshe, N., Oun, A., Sabogal-Guáqueta, A. M., Trombetta-Lima, M., Mitchel, S. C., Adzemovic, A., Speek, O., Morra, F., van der Veen, C. H. J. T., Lezoualc'h, F., Cheng, X., Schmidt, M. & Dolga, A. M., 4-Feb-2022, In: Antioxidants (Basel, Switzerland). 11, 2, 20 p., 314.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Citations (Scopus)55 Downloads (Pure) -
The multifaceted role of LRRK2 in Parkinson's disease: From human iPSC to organoids
Oun, A., Sabogal-Guaqueta, A. M., Galuh, S., Alexander, A., Kortholt, A. & Dolga, A. M., 15-Oct-2022, In: Neurobiology of Disease. 173, 14 p., 105837.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Citations (Scopus)31 Downloads (Pure)