Antoon van Oosterhout

Search results

• 2011

  Role of aberrant metalloproteinase activity in the pro-inflammatory phenotype of bronchial epithelium in COPD

  Heijink, I. H., Brandenburg, S. M., Noordhoek, J. A., Slebos, D-J., Postma, D. S. & van Oosterhout, A. J., 23-Aug-2011, In: Respiratory Research. 12, 11 p., 110.

  Research output: Contribution to journal › Article › Academic › peer-review

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  16 Citations (Scopus)

  243 Downloads (Pure)

• Role of regulatory T-cells in immunization strategies involving a recombinant alphavirus vector system

  Walczak, M., Regts, J., van Oosterhout, A. J. M., Boon, L., Wilschut, J., Nijman, H. W. & Daemen, T., 2011, In: Antiviral therapy. 16, 2, p. 207-218 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  17 Citations (Scopus)
• 2010

  Characterisation of cell adhesion in airway epithelial cell types using electric cell-substrate impedance sensing

  Heijink, I. H., Brandenburg, S. M., Noordhoek, J. A., Postma, D. S., Slebos, D-J. & van Oosterhout, A. J. M., Apr-2010, In: European Respiratory Journal. 35, 4, p. 894-903 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  118 Citations (Scopus)

• Cryopreservation does not alter the frequency of regulatory T cells in peripheral blood mononuclear cells

  Van Hemelen, D., Oude Elberink, H. N. G., Heimweg, J., van Oosterhout, A. J. M. & Nawijn, M. C., 28-Feb-2010, In: Journal of Immunological Methods. 353, 1-2, p. 138-140 3 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  27 Citations (Scopus)

• Epidermal growth factor receptor signalling contributes to house dust mite-induced epithelial barrier dysfunction

  Heijink, I. H., van Oosterhout, A. & Kapus, A., Nov-2010, In: European Respiratory Journal. 36, 5, p. 1016-1026 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  90 Citations (Scopus)

• Gene-gene interaction in regulatory T-cell function in atopy and asthma development in childhood

  Bottema, R. W. B., Kerkhof, M., Reijmerink, N. E., Thijs, C., Smit, H. A., van Schayck, C. P., Brunekreef, B., van Oosterhout, A. J., Postma, D. S. & Koppelman, G. H., Aug-2010, In: Journal of Allergy and Clinical Immunology. 126, 2, p. 338-U62 19 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  48 Citations (Scopus)

• Suppression of Th2-Driven Airway Inflammation by Allergen Immunotherapy Is Independent of B Cell and Ig Responses in Mice

  Shirinbak, S., Taher, Y. A., Maazi, H., Gras, R., van Esch, B. C. A. M., Henricks, P. A. J., Samsom, J. N., Verbeek, J. S., Lambrecht, B. N., van Oosterhout, A. J. M. & Nawijn, M. C., 1-Oct-2010, In: Journal of Immunology. 185, 7, p. 3857-3865 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  26 Citations (Scopus)
• 2009

  Change in inflammation in out-patient COPD patients from stable phase to a subsequent exacerbation

  Bathoorn, E., Liesker, J. J. W., Postma, D. S., Koëter, G. H., van der Toorn, M., van der Heide, S., Ross, H. A., van Oosterhout, A. J. M. & Kerstjens, H. A. M., 2-Feb-2009, In: International Journal of Chronic Obstructive Pulmonary Disease. 4, p. 101-109 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  65 Citations (Scopus)

  215 Downloads (Pure)

• GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma

  Motta, A. C., Vissers, J. L. M., Gras, R., Van Esch, B. C. A. M., Van Oosterhout, A. J. M. & Nawijn, M. C., 7-Oct-2009, In: Respiratory Research. 10, 8 p., 93.

  Research output: Contribution to journal › Article › Academic › peer-review

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  27 Citations (Scopus)

  193 Downloads (Pure)

• Identification of PCDH1 as a Novel Susceptibility Gene for Bronchial Hyperresponsiveness

  Koppelman, G. H., Meyers, D. A., Howard, T. D., Zheng, S. L., Hawkins, G. A., Ampleford, E. J., Xu, J., Koning, H., Bruinenberg, M., Nolte, I. M., van Diemen, C. C., Boezen, H. M., Timens, W., Whittaker, P. A., Stine, O. C., Bartons, S. J., Holloway, J. W., Holgate, S. T., Graves, P. E., Martinez, F. D., & 3 othersvan Oosterhout, A. J., Bleecker, E. R. & Postma, D. S., 15-Nov-2009, In: American Journal of Respiratory and Critical Care Medicine. 180, 10, p. 929-935 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  105 Citations (Scopus)

• Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells

  van der Toorn, M., Rezayat, D., Kauffman, H. F., Bakker, S. J. L., Gans, R. O. B., Koeter, G. H., Choi, A. M. K., van Oosterhout, A. J. M. & Slebos, D-J., Jul-2009, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 297, 1, p. L109-L114 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  128 Citations (Scopus)

• Preeclampsia is Associated with lower Percentages of Regulatory T Cells in Maternal Blood

  Prins, J. R., Boelens, H. M., Heimweg, J., Van der Heide, S., Dubois, A. E., Van Oosterhout, A. J. & Erwich, J. J. H. M., 2009, In: HYPERTENSION IN PREGNANCY. 28, 3, p. 300-311 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  120 Citations (Scopus)

  383 Downloads (Pure)

• The role of female sex hormones in the development and severity of allergic and non-allergic asthma

  van den Berge, M., Heijink, H. I., van Oosterhout, A. J. M. & Postma, D. S., Oct-2009, In: Clinical and Experimental Allergy. 39, 10, p. 1477-1481 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  45 Citations (Scopus)
• 2008

  1 alpha,25-dihydroxyvitamin D(3) potentiates the beneficial effects of allergen immunotherapy in a mouse model of allergic asthma: Role for IL-10 and TGF-beta

  Taher, Y. A., van Esch, B. C. A. M., Hofman, G. A., Henricks, P. A. J. & van Oosterhout, A. J. M., 15-Apr-2008, In: Journal of Immunology. 180, 8, p. 5211-5221 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  158 Citations (Scopus)

• Anti-inflammatory Effects of Combined Budesonide/Formoterol in COPD Exacerbations

  Bathoorn, E., Liesker, J. J. W., Postma, D. S., Boorsma, M., Bondesson, E., Koeter, G. H., Kauffman, H. F., van Oosterhout, A. J. M. & Kerstjens, H. A. M., Oct-2008, In: COPD: Journal of Chronic Obstructive Pulmonary Disease. 5, 5, p. 282-290 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  32 Citations (Scopus)

• Indoleamine 2,3-dioxygenase-dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model

  Taher, Y. A., Piavaux, B. J. A., Gras, R., van Esch, B. C. A. M., Hofman, G. A., Bloksma, N., Henricks, P. A. J. & van Oosterhout, A. J. M., Apr-2008, In: Journal of Allergy and Clinical Immunology. 121, 4, p. 983-991 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  66 Citations (Scopus)

• Poly(ethylene glycol)-Based Stable Isotope Labeling Reagents for the Quantitative Analysis of Low Molecular Weight Metabolites by LC-MS

  Abello, N., Geurink, P. P., van der Toorn, M., van Oosterhout, A. J. M., Lugtenburg, J., van der Marel, G. A., Kerstjens, H. A. M., Postma, D. S., Overkleeft, H. S. & Bischoff, R., 1-Dec-2008, In: Analytical Chemistry. 80, 23, p. 9171-9180 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  33 Citations (Scopus)
• 2007

  Anti-inflammatory effects of inhaled carbon monoxide in patients with COPD: a pilot study

  Bathoorn, E., Slebos, D-J., Postma, D. S., Koeter, G. H., van Oosterhout, A. J. M., van der Toorn, M., Boezen, H. M. & Kerstjens, H. A. M., Dec-2007, In: European Respiratory Journal. 30, 6, p. 1131-1137 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  150 Citations (Scopus)

• Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis

  van der Toorn, M., Slebos, D-J., de Bruin, H. G., Leuvenink, H. G., Bakker, S. J. L., Gans, R. O. B., Koeter, G. H., van Oosterhout, A. J. M. & Kauffman, H. F., May-2007, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 292, 5, p. L1211-L1218 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  117 Citations (Scopus)

• Cigarette smoke irreversibly modifies glutathione in airway epithelial cells

  van der Toorn, M., Vries, M. P. S., Slebos, D-J., de Bruin, H. G., Abello, N., van Oosterhout, A. J. M., Bischoff, R. & Kauffman, H. F., Nov-2007, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 293, 5, p. L1156-L1162 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  94 Citations (Scopus)

• Der p, IL-4, and TGF-beta cooperatively induce EGFR-dependent TARC expression in airway epithelium

  Heijink, I., Kies, P. M., van Oosterhout, A. J. M., Postma, D. S., Kauffman, H. F. & Vellenga, E., Mar-2007, In: American Journal of Respiratory Cell and Molecular Biology. 36, 3, p. 351-359 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  55 Citations (Scopus)

• Down-regulation of E-cadherin in human bronchial epithelial cells leads to epidermal growth factor receptor-dependent Th2 cell-promoting activity

  Heijink, I. H., Kies, P. M., Kauffman, H. F., Postma, D. S., van Oosterhout, A. J. M. & Vellenga, E., 15-Jun-2007, In: Journal of Immunology. 178, 12, p. 7678-7685 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  131 Citations (Scopus)

• Mouse genetic model for antigen-induced airway manifestations of asthma

  Piavaux, B., Jeurink, P. V., Groot, P. C., Hofman, G. A., Demant, P. & Van Oosterhout, A. J. M., Jan-2007, In: GENES AND IMMUNITY. 8, 1, p. 28-34 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  9 Citations (Scopus)

• Safety of sputum induction during exacerbations of COPD

  Bathoorn, E., Liesker, J., Postma, D., Koeter, G., van Oosterhout, A. J. M. & Kerstjens, H. A. M., Feb-2007, In: Chest. 131, 2, p. 432-438 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  31 Citations (Scopus)
• 2006

  Macrophage reprogramming by mycolic acid promotes a tolerogenic response in experimental asthma

  Korf, J. E., Pynaert, G., Tournoy, K., Boonefaes, T., Van Oosterhout, A., Ginneberge, D., Haegeman, A., Verschoor, J. A., De Baetselier, P. & Grooten, J., 15-Jul-2006, In: American Journal of Respiratory and Critical Care Medicine. 174, 2, p. 152-160 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  46 Citations (Scopus)

• Strategies for targeting T-cells in allergic diseases and asthma

  Heijink, I. H. & Van Oosterhout, A. J. M., Nov-2006, In: Pharmacology & Therapeutics. 112, 2, p. 489-500 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)

• T cells in asthma: Lessons from mouse models

  Motta, A. C. & Van Oosterhout, A. J. M., 2006, In: Drug Discovery Today: Disease Models. 3, 3, p. 199 - 204

  Research output: Contribution to journal › Article › Academic › peer-review
  2 Citations (Scopus)
• 2005

  Macrophages induce and long-term suppression in a mouse asthma model

  Vissers, JLM., van Esch, BCAM., Hofman, GA. & van Oosterhout, AJM., Dec-2005, In: European Respiratory Journal. 26, 6, p. 1040-1046 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  18 Citations (Scopus)
• 2004

  Allergen immunotherapy induces a suppressive memory response mediated by IL-10 in a mouse asthma model

  Vissers, J. L. M., van Esch, B. C. A. M., Hofman, G. A., Kapsenberg, M. L., Weller, F. R. & Van Oosterhout, A. J. M., 2004, In: Journal of Allergy and Clinical Immunology. 113, 6, p. 1204 - 1210 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  68 Citations (Scopus)

• Cytotoxic T lymphocyte antigen 4 polymorphisms and allergic asthma

  Van Oosterhout, A. J. M., Deurloo, D. T. & Groot, P. C., 2004, In: Clinical and Experimental Allergy. 34, 1, p. 4 - 8 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  12 Citations (Scopus)

• Role of T cell co-stimulation in murine models of allergic asthma

  Deurloo, D. T. & Van Oosterhout, A. J. M., 2004, In: Clinical and Experimental Allergy. 34, 1, p. 17 - 25 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  8 Citations (Scopus)

• Stimulation of allergen-loaded macrophages by TLR9-ligand potentiates IL-10-mediated suppression of allergic airway inflammation in mice

  Vissers, JLM., van Esch, BCAM., Jeurink, PV., Hofman, GA. & van Oosterhout, AJM., 11-Nov-2004, In: Respiratory Research. 5, 21, 8 p., 21.

  Research output: Contribution to journal › Article › Academic › peer-review

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  22 Citations (Scopus)

  202 Downloads (Pure)
• 2003

  CD28/CTLA4 double deficient mice demonstrate crucial role for B7 co-stimulation in the induction of allergic lower airways disease

  Deurloo, DT., van Berkel, MAT., van Esch, BCAM., Hofhuis, F., Nijkamp, FP., Oosterwegel, MA. & van Oosterhout, AJM., Sept-2003, In: Clinical and Experimental Allergy. 33, 9, p. 1297-1304 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  19 Citations (Scopus)
• 2001

  Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice

  Muijsers, RBR., van Ark, N. V., Folkerts, G., Koster, AS., van Oosterhout, AJM., Postma, DS. & Nijkamp, FP., Sept-2001, In: British Journal of Pharmacology. 134, 2, p. 434-440 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  49 Citations (Scopus)
• 1989

  Endotoxin-induced reduction of beta-adrenergic binding sites on splenic lymphocytes in vivo and in vitro: its modulation by anterior hypothalamic lesions

  Van Oosterhout, A. J., Van Heuven-Nolsen, D., Thijssen, J. H., Nijkamp, F. P. & de Boer, S. F., 1989, In: Life Sciences. 44, 1, p. 57-65 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  2 Citations (Scopus)

• Endotoxin-Induced Reduction of β-Adrenergic Binding Sites on Splenic Lymphocytes In Vivo and In Vitro: Its Modulation by Anterior Hypothalamic Lesions

  Oosterhout, A. J. M. V., Heuven-Nolsen, D. V., Boer, S. F. D., Thijssen, J. H. H. & Nijkamp, F. P., 1989, In: Life Sciences. 44, 1, p. 57-65 9 p.

  Research output: Contribution to journal › Article › Academic

  Open Access

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  2 Citations (Scopus)

  270 Downloads (Pure)