Arno Bourgonje – Research output — the University of Groningen research portal

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55 Article
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2022

Biomarkers of neutrophil activity and extracellular matrix turnover predict long-term response to vedolizumab in patients with Crohn's disease
Alexdóttir, M. S., Bourgonje, A. R., Karsdal, M. A., Bay-Jensen, A-C., Pehrsson, M., Loveikyte, R., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., Faber, K. N., Dijkstra, G. & Mortensen, J. H., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S468-S469 2 p.
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In-depth characterisation of the serum antibody epitope repertoire in Inflammatory Bowel Disease by high-throughput phage-displayed immunoprecipitation sequencing
Bourgonje, A. R., Andreu-Sánchez, S., Vogl, T., Hu, S., Vich Vila, A., Leviatan, S., Kurilshchikov, A., Klompus, S., Kalka, I. N., van Dullemen, H. M., Weinberger, A., Visschedijk, M. C., Festen, E. A. M., Faber, K. N., Wijmenga, C., Dijkstra, G., Segal, E., Fu, J., Zhernakova, A. & Weersma, R. K., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S100-S102 3 p.
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Mucosal eosinophil abundance in non-inflamed colonic tissue predicts response to vedolizumab induction therapy in inflammatory bowel disease
Gabriëls, R. Y., Bourgonje, A. R., von Martels, J. Z. H., Blokzijl, T., Weersma, R. K., Galinsky, K., Juarez, J., Faber, K. N., Kats-Ugurlu, G. & Dijkstra, G., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S517-S518 2 p.
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Mucosal microbiota modulate host intestinal immune signatures in Inflammatory Bowel Disease
Hu, S., Bourgonje, A. R., Gacesa, R., Jansen, B. H., Bangma, A., Hidding, I., Festen, E. A. M., van Dullemen, H. M., Visschedijk, M. C., Dijkstra, G., Harmsen, H. J. M., Vich Vila, A., Spekhorst, L. M. & Weersma, R. K., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S185-S186 2 p.
Research output: Contribution to journal › Meeting Abstract › Academic

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Patients with Inflammatory Bowel Disease show IgG immune responses towards disease-associated small intestinal bacteria
Bourgonje, A. R., Roo-Brand, G., Lisotto, P., Sadaghian Sadabad, M., Reitsema, R. D., de Goffau, M. C., Faber, K. N., Dijkstra, G. & Harmsen, H. J. M., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S179-S180 2 p.
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Proteomic analyses do not reveal subclinical inflammation in fatigued patients with quiescent Inflammatory Bowel Disease
Bourgonje, A. R., Wichers, S. J., Hu, S., van Dullemen, H. M., Visschedijk, M. C., Faber, K. N., Festen, E. A. M., Dijkstra, G., Samsom, J. N., Weersma, R. K. & Spekhorst, L. M., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S284-S285 2 p.
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Serological biomarkers of type VI and XXII collagen formation predict and monitor infliximab treatment response in patients with Crohn's disease
Alexdóttir, M. S., Bourgonje, A. R., Karsdal, M. A., Bay-Jensen, A-C., Pehrsson, M., Loveikyte, R., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., Faber, K. N., Dijkstra, G. & Mortensen, J. H., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S541 1 p.
Research output: Contribution to journal › Meeting Abstract › Academic

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The effect of induction therapy with infliximab or vedolizumab on hepcidin and iron status in patients with Inflammatory Bowel Disease
Loveikyte, R., Bourgonje, A. R., van der Reijden, J. J., Bulthuis, M. L. C., Hawinkels, L. J. A. C., van Goor, H., van der Meulen-de Jong, A. E. & Dijkstra, G., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S244-S245 2 p.
Research output: Contribution to journal › Meeting Abstract › Academic

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Type I collagen degradation fragments (C1M) and human neutrophil elastase-derived fragments of calprotectin (CPa9-HNE) reflect biochemical and endoscopic disease activity in patients with Inflammatory Bowel Disease
Bourgonje, A. R., Alexdóttir, M. S., Loveikyte, R., Pehrsson, M., Bay-Jensen, A-C., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., Karsdal, M. A., Faber, K. N., Mortensen, J. H. & Dijkstra, G., 21-Jan-2022, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S214-S215 2 p.
Research output: Contribution to journal › Meeting Abstract › Academic

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2021

Biomarkers reflecting extracellular matrix turnover and inflammation can be used to monitor disease activity and treatment response in patients with Crohn's disease undergoing infliximab induction therapy
Alexdóttir, M. S., Bourgonje, A. R., Karsdal, M. A., Bay-Jensen, A-C., Faber, K. N., Loveikyte, R., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., Dijkstra, G. & Mortensen, J. H., May-2021, In: Journal of Crohn's and Colitis. 15, Suppl(1), p. S453-S454 2 p.
Research output: Contribution to journal › Meeting Abstract › Academic
Safety and drug survival of methotrexate versus tioguanine after failure of conventional thiopurines in patients with Crohn's disease
Savelkoul, E., Maas, M., Bourgonje, A. R., Crouwel, F., Russel, M. G. V. M., Römkens, T. E. H., de Boer, N. K. H., Dijkstra, G. & Hoentjen, F., May-2021, In: Journal of Crohn's and Colitis. 15, Suppl(1), p. S390-S391
Research output: Contribution to journal › Meeting Abstract › Academic
Serological biomarkers of type III and IV collagen remodeling predict and monitor infliximab treatment response in patients with Inflammatory Bowel Disease
Alexdóttir, M. S., Bourgonje, A. R., Karsdal, M. A., Bay-Jensen, A-C., Faber, K. N., Loveikyte, R., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., Dijkstra, G. & Mortensen, J. H., May-2021, In: Journal of Crohn's and Colitis. 15, Suppl(1), p. S403-S404 2 p.
Research output: Contribution to journal › Meeting Abstract › Academic
The effect of phenotype and genotype on the plasma proteome in patients with Inflammatory Bowel Disease
Bourgonje, A. R., Hu, S., Spekhorst, L. M., Zhernakova, D., Vich Vila, A., Li, Y., Voskuil, M. D., van Berkel, L. A., Bley Folly, B., Charrout, M., Mahfouz, A., Reinders, M. J. T., van Heck, J. I. P., Joosten, L. A. B., Visschedijk, M. C., van Dullemen, H. M., Faber, K. N., Samsom, J. N., Festen, E. A. M., Dijkstra, G., & 1 othersWeersma, R. K., May-2021, In: Journal of Crohn's and Colitis. 15, Suppl(1), p. S036-S039 4 p.
Research output: Contribution to journal › Meeting Abstract › Academic
Type I collagen degradation fragments and type IV collagen formation/degradation ratio are serological biomarkers for stricturing (Montreal B2) Crohn's disease
Bourgonje, A. R., Alexdóttir, M. S., Loveikyte, R., Bay-Jensen, A-C., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., Karsdal, M. A., Faber, K. N., Mortensen, J. H. & Dijkstra, G., May-2021, In: Journal of Crohn's and Colitis. 15, Suppl(1), p. S214-S215
Research output: Contribution to journal › Meeting Abstract › Academic
Type IV collagen formation/degradation ratio predicts response to infliximab induction therapy in patients with Ulcerative Colitis
Bourgonje, A. R., Alexdóttir, M. S., Loveikyte, R., Bay-Jensen, A-C., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., Karsdal, M. A., Faber, K. N., Mortensen, J. H. & Dijkstra, G., May-2021, In: Journal of Crohn's and Colitis. 15, Suppl(1), p. S309-S310 2 p.
Research output: Contribution to journal › Meeting Abstract › Academic
Use of TNF-α-antagonists and systemic steroids is associated with attenuated imunogenicity against SARS-CoV-2 in fully vaccinated patients with Inflammatory Bowel Disease
Otten, A. T., Bourgonje, A. R., Horinga, P. P., van der Meulen, H. H., van Leer-Buter, C. C., Dijkstra, G. & Visschedijk, M. C., 22-Jan-2021, In: Journal of Crohn's and Colitis. 16, Suppl(1), p. S538 1 p.
Research output: Contribution to journal › Meeting Abstract › Academic

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2020

Systemic iron deficiency and intestinal inflammation control gut mucosal HIF-1α and TFRC activation in inflammatory bowel disease
Bourgonje, A. R., Fagundes Rosa, R. R., Hu, S., Barbieri, R., Jansen, B. H., Blokzijl, T., Taylor, C. T., Faber, K. N. & Dijkstra, G., 11-Oct-2020, In: United European Gastroenterology Journal. 8, 8(Suppl), p. 9-10 2 p., OP004.
Research output: Contribution to journal › Meeting Abstract › Academic
2019

A combined set of four serum inflammatory biomarkers reliably predicts endoscopic disease activity in inflammatory bowel disease
Bourgonje, A. R., von Martels, J. Z. H., Gabriëls, R. Y., Blokzijl, T., Buist-Homan, M., Heegsma, J., Jansen, B. H., van Dullemen, H. M., Festen, E. A. M., Visschedijk, M. C., Weersma, R. K., de Vos, P., Faber, K. N. & Dijkstra, G., 25-Jan-2019, In: Journal of Crohn's and Colitis. 13, 1
Research output: Contribution to journal › Meeting Abstract › Academic
A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease
Bourgonje, A. R., Gabriëls, R. Y., von Martels, J. Z. H., Blokzijl, T., Buist-Homan, M., Heegsma, J., Jansen, B. H., van Dullemen, H. M., Festen, E. A. M., Visschedijk, M. C., Weersma, R. K., de Vos, P., Faber, K. N. & Dijkstra, G., May-2019, In: Gastroenterology. 156, 6, p. S848 1 p., Mo1814.
Research output: Contribution to journal › Meeting Abstract › Academic
Combining absolute quantification of fecal bacteria with metagenomic sequencing data improves the characterization of the gut microbiome of patients with Crohn’s disease
Vich Vila, A., Boddeke, A., Kurilshikov, A., Collij, V., Sureda Horrach, P., Martels ,von, J. Z. H., Bourgonje, A. R., Klaassen, M. A. Y., Hu, S., Jansen, D., Faber, K. N., Dijkstra, G., Zhernakova, S., Harmsen, H. J. M. & Weersma, R. K., Oct-2019, In: United European Gastroenterology Journal.
Research output: Contribution to journal › Meeting Abstract › Academic
Eosinophil counts in colon biopsies can predict treatment response to vedolizumab in Inflammatory Bowel Disease
Gabriëls, R. Y., Bourgonje, A. R., Trentadue, G., Faber, K. N., Dijkstra, G. & Kats-Ugurlu, G., Sept-2019, In: Virchows Archiv. 475, Suppl 1, p. S199-S200 2 p.
Research output: Contribution to journal › Meeting Abstract › Academic
Eotaxin-1 and mucosal eosinophil abundance predict treatment response to vedolizumab in Inflammatory Bowel Disease
Gabriëls, R. Y., Bourgonje, A. R., von Martels, J. Z. H., Trentadue, G., Blokzijl, T., Dullemen, van, H. M., Festen, E. A. M., Visschedijk, M. C., Weersma, R. K., Kats-Ugurlu, G., Faber, K. N. & Dijkstra, G., Oct-2019, In: United European Gastroenterology Journal.
Research output: Contribution to journal › Meeting Abstract › Academic
Genome-wide analyses identify novel genetic variants that interact with tobacco smoke and affect risk for development of inflammatory bowel disease
Visser, F. C. W., Voskuil, M., Bourgonje, A. R., Li, Y., Weersma, R. K. & Festen, E. A. M., Oct-2019, In: United European Gastroenterology Journal.
Research output: Contribution to journal › Meeting Abstract › Academic
Levels of serum free thiols are superior to fecal calprotectin in predicting endoscopic disease activity in Inflammatory Bowel Disease
Bourgonje, A. R., Gabriëls, R. Y., de Borst, M. H., Bulthuis, M. L. C., Faber, K. N., Dijkstra, G. & van Goor, H., Jun-2019, In: ISANH - Archives. 6, 3, p. 51 1 p.
Research output: Contribution to journal › Meeting Abstract › Academic
Levels of serum free thiols are superior to fecal calprotectin in predicting endoscopic disease activity in Inflammatory Bowel Disease
Bourgonje, A. R., Gabriëls, R. Y., Borst, de, M. H., Bulthuis, M. L. C., Faber, K. N., van Goor, H. & Dijkstra, G., Oct-2019, In: United European Gastroenterology Journal. 7, 8(Suppl), p. 137-138 P0352.
Research output: Contribution to journal › Meeting Abstract › Academic

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Reconstitution of Prebiotic-Driven Host-Microbe Syntrophy in the Colon; Inulin-Grown Faecalibacterium prausnitzii Cross-Feeds the Human Intestinal Epithelium
Fagundes Rosa, R. R., Bourgonje, A. R., Sadaghian Sadabad, M., van Leeuwen, S. S., Harmsen, H. J. M., Dijkstra, G. & Faber, K. N., May-2019, In: Gastroenterology. 156, 6, p. S895 1 p., Mo1946.
Research output: Contribution to journal › Meeting Abstract › Academic
Redox status in human disease and its relation to body mass index
van Goor, H., Pasch, A., Bourgonje, A. R. & Saleh, J., Jun-2019, In: ISANH - Archives. 6, 3, p. 58 1 p.
Research output: Contribution to journal › Meeting Abstract › Academic
Riboflavin suppresses inflammation and attenuates Crohn’s disease symptoms (RISE-UP Study)
von Martels, J. Z. H., Bourgonje, A. R., Klaassen, M. A. Y., Alkhalifah, H. A. A., Sadaghian Sadabad, M., Vich Vila, A., Gacesa, R., Gabriels, R. Y., Steinert, R. E., Jansen, B. H., Bulthuis, M. L. C., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., de Vos, P., van Goor, H., Faber, K. N., Harmsen, H. J. M. & Dijkstra, G., Oct-2019, In: United European Gastroenterology Journal. 7, 8(Suppl), p. 460-461 2 p., P0683.
Research output: Contribution to journal › Meeting Abstract › Academic
Systemic iron deficiency is associated with activation of the HIF-1α pathway in the intestinal mucosa of patients with Inflammatory Bowel Disease
Fagundes Rosa, R. R., Bourgonje, A. R., Barbieri, R., Jansen, D., Taylor, C. T., Faber, K. N. & Dijkstra, G., Oct-2019, In: United European Gastroenterology Journal.
Research output: Contribution to journal › Meeting Abstract › Academic
The Intestinal Microenvironment Induces a Transcription Reprogramming of Epithelial Oxygen Sensing
Fagundes Rosa, R. R., Bourgonje, A. R., Cui, Y., Blokzijl, T., Harmsen, H. J. M., Dijkstra, G., Taylor, C. T. & Faber, K. N., May-2019, In: Gastroenterology. 156, 6, p. S37 1 p., 157.
Research output: Contribution to journal › Meeting Abstract › Academic