Carolina Elzinga

2023

Negative modulation of mitochondrial calcium uniporter complex protects neurons against ferroptosis

Marmolejo-Garza, A., Krabbendam, I. E., Luu, M. D. A., Brouwer, F., Trombetta-Lima, M., Unal, O., O’Connor, S. J., Majerníková, N., Elzinga, C. R. S., Mammucari, C., Schmidt, M., Madesh, M., Boddeke, E. & Dolga, A. M., Nov-2023, In: Cell Death and Disease. 14, 11, 15 p., 772.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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10 Citations (Scopus)

53 Downloads (Pure)

2021

Effects of (a Combination of) the Beta2-Adrenoceptor Agonist Indacaterol and the Muscarinic Receptor Antagonist Glycopyrrolate on Intrapulmonary Airway Constriction

Maarsingh, H., Oldenburger, A., Han, B., Zuidhof, A. B., Elzinga, C. R. S., Timens, W., Meurs, H., Sopi, R. B. & Schmidt, M., 2021, In: Cells. 10, 5, 18 p., 1237.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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5 Citations (Scopus)

75 Downloads (Pure)

2020

Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle

Baarsma, H. A., Han, B., Poppinga, W. J., Driessen, S., Elzinga, C. R. S., Halayko, A. J., Meurs, H., Maarsingh, H. & Schmidt, M., 9-Apr-2020, In: Frontiers in Cell and Developmental Biology. 8, p. 165 13 p., 165.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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4 Citations (Scopus)

132 Downloads (Pure)

2019

Second M-3 muscarinic receptor binding site contributes to bronchoprotection by tiotropium

Kistemaker, L. E. M., Elzinga, C. R. S., Tautermann, C. S., Pieper, M. P., Seeliger, D., Alikhil, S., Schmidt, M., Meurs, H. & Gosens, R., Aug-2019, In: British Journal of Pharmacology. 176, 16, p. 2864-2876 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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8 Citations (Scopus)

107 Downloads (Pure)

Small airway hyperresponsiveness in COPD: Relationship between structure and function in lung slices

Maarsingh, H., Bidan, C. M., Brook, B. S., Zuidhof, A. B., Elzinga, C. R. S., Smit, M., Oldenburger, A., Gosens, R., Timens, W. & Meurs, H., Mar-2019, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 316, 3, p. L537-L546 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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29 Citations (Scopus)

324 Downloads (Pure)

2016

A-Kinase Anchoring Proteins Coordinate the Contractile Phenotype of Airway Smooth Muscle

Poppinga, W. J., Han, B., Elzinga, C. R., Halayko, A. J., Meurs, H. & Schmidt, M., Apr-2016, In: The FASEB Journal. 30, 1 Supplement, p. 969.29 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Open Access

Epac1 And Epac2 Regulate Airway Smooth Muscle Tone In Mice

Schmidt, M., Oldenburger, A., Elzinga, C. & Maarsingh, H., 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Scaffolding Protein A-Kinase Anchoring Protein 12 Enhances beta 2-Adrenoceptor Sensitivity In Tracheal Smooth Muscle

Schmidt, M., Poppinga, W. J., Elzinga, C., Meurs, H. & Maarsingh, H., 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Small Airway Hyperresponsiveness In Precision-Cut Lung Slices Of Patients With Mild To Moderate COPD: Relationship Between Tissue Structure And Function

Meurs, H., Zuidhof, A. B., Elzinga, C. R. S., Smit, M., Oldenburger, A., Bidan, C. M., Gosens, R., Timens, W. & Maarsingh, H., 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p.

Research output: Contribution to journal › Meeting Abstract › Academic

2015

Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization

Jansen, S. R., Holman, R., Hedemann, I., Frankes, E., Elzinga, C. R. S., Timens, W., Gosens, R., de Bont, E. S. & Schmidt, M., Jan-2015, In: Journal of cellular and molecular medicine. 19, 1, p. 210-226 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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17 Citations (Scopus)

311 Downloads (Pure)

β3-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BKCa channels and Rho kinase

Cernecka, H., Kersten, K., Maarsingh, H., Elzinga, C. R., de Jong, I. J., Korstanje, C., Michel, M. C. & Schmidt, M., Jul-2015, In: Naunyn-Schmiedebergs Archives of Pharmacology. 388, 7, p. 749-759 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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22 Citations (Scopus)

178 Downloads (Pure)

2011

Epac as a novel effector of airway smooth muscle relaxation

Roscioni, S. S., Maarsingh, H., Elzinga, C. R. S., Schuur, J., Menzen, M., Halayko, A. J., Meurs, H. & Schmidt, M., Jul-2011, In: Journal of cellular and molecular medicine. 15, 7, p. 1551-1563 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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63 Citations (Scopus)

232 Downloads (Pure)

Protein kinase A and the exchange protein directly activated by cAMP (Epac) modulate phenotype plasticity in human airway smooth muscle

Roscioni, S. S., Prins, A. G., Elzinga, C. R. S., Menzen, M. H., Dekkers, B. G. J., Halayko, A. J., Meurs, H., Maarsingh, H. & Schmidt, M., Oct-2011, In: British Journal of Pharmacology. 164, 3, p. 958-969 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

26 Citations (Scopus)

2009

(Endo)cannabinoids mediate different Ca(2+) entry mechanisms in human bronchial epithelial cells

Gkoumassi, E., Dekkers, B. G. J., Droge, M. J., Elzinga, C. R. S., Hasenbosch, R. E., Meurs, H., Nelemans, S. A., Schmidt, M. & Zaagsma, J., Jul-2009, In: Naunyn-Schmiedebergs Archives of Pharmacology. 380, 1, p. 67-77 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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7 Citations (Scopus)

63 Downloads (Pure)

A role of AKAP5 in PKA and Epac mediated PKB/Akt phosphorylation in the lung

Bosma, W. J., Menzen, M., Roscioni, S. S., Elzinga, C. R. S., Nijholt, I. M., Eisel, U. L. M., Halayko, A. J., Meurs, H. & Schmidt, M., 2009, p. A2055-A2055. 1 p.

Research output: Contribution to conference › Poster › Academic

Open Access

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279 Downloads (Pure)

PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells

Roscioni, S. S., Kistemaker, L. E. M., Menzen, M. H., Elzinga, C. R. S., Gosens, R., Halayko, A. J., Meurs, H. & Schmidt, M., 29-Sept-2009, In: Respiratory Research. 10, 17 p., 88.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

34 Citations (Scopus)

237 Downloads (Pure)

2008

Epac: effectors and biological functions

Roscioni, S. S., Elzinga, C. R. S. & Schmidt, M., Jun-2008, In: Naunyn-Schmiedebergs Archives of Pharmacology. 377, 4-6, p. 345-357 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

122 Citations (Scopus)

2007

Virodhamine and CP55,940 modulate cAMP production and IL-8 release in human bronchial epithelial cells

Gkoumassi, E., Dekkers, B. G. J., Droege, M. J., Elzinga, C. R. S., Schmidt, M., Meurs, H., Zaagsma, J. & Nelemans, S. A., Aug-2007, In: British Journal of Pharmacology. 151, 7, p. 1041-1048 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

23 Citations (Scopus)

2005

Potentation of ß-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C

Boterman, M., Elzinga, C. R. S., Wagemakers, D., Eppens, P. B., Zaagsma, H. & Meurs, H., 23-May-2005, In: European Journal of Pharmacology. 516, 1, p. 85-92 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

31 Citations (Scopus)

2001

Muscarinic receptor-Beta-adrenoceptor cross-talk in airways smooth muscle

Meurs, H. & Elzinga, C. R. S., 2001, Muscarinic Receptors in Airways Diseases. Meurs, H., Roffel, A. F. & Zaagsma, J. (eds.). Basel: Birkhauser, p. 121 - 157 37 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

2000

ß-Agonist-induced constitutive ß₂-adrenergic receptor activity in bovine tracheal smooth muscle

de Vries, B., Meurs, H., Roffel, A. F., Elzinga, C. R. S., Hoiting, B. H., de Vries, M. M. L. & Zaagsma, J., Nov-2000, In: British Journal of Pharmacology. 131, 5, p. 915-920 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

10 Citations (Scopus)

Up-regulation of airway smooth muscle histamine H₁receptor mRNA, protein and function by ß₂-adrenoceptor activation

Mak, J. C. W., Roffel, A. F., Katsunuma, T., Elzinga, C. R. S., Zaagsma, J. & Barnes, P. J., May-2000, In: Molecular Pharmacology. 57, 5, p. 857-864 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

41 Citations (Scopus)

1999

β₂-adrenoceptor agonist-induced upregulation of tachykinin NK₂ receptor expression and function in airway smooth muscle

Katsunuma, T., Roffel, A. F., Elzinga, C. R. S., Zaagsma, J., Barnes, P. J. & Mak, J. C. W., Sept-1999, In: American Journal of Respiratory Cell and Molecular Biology. 21, 3, p. 409-417 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

31 Citations (Scopus)

1997

Characterization of the muscarinic receptor subtype(s) mediating contraction of the guinea-pig lung strip and inhibition of acetylcholine release in the guinea-pig trachea with the selective muscarinic receptor antagonist tripitramine

Roffel, A. F., Davids, J. H., Elzinga, C. R. S., Wolf, D., Zaagsma, J. & Kilbinger, H., Sept-1997, In: British Journal of Pharmacology. 122, 1, p. 133-141 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

19 Citations (Scopus)

1996

Modulation of agonist-induced phosphoinositide metabolism, Ca²⁺ signalling and contraction of airway smooth muscle by cyclic AMP-dependent mechanisms

Hoiting, B. H., Meurs, H., Schuiling, M., Kuipers, R., Elzinga, C. R. S. & Zaagsma, J., Feb-1996, In: British Journal of Pharmacology. 117, 3, p. 419-426 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

44 Citations (Scopus)

1995

Feedforward control of agonist-induced Ca²⁺ signalling by protein kinase C in airway smooth muscle cells

Hoiting, B. H., Kuipers, R., Elzinga, C. R. S., Zaagsma, J. & Meurs, H., 18-Jul-1995, In: European journal of pharmacology-Molecular pharmacology section. 290, 2, p. R5-R7 3 p.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

9 Citations (Scopus)

No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea

Roffel, A. F., Meurs, H., Elzinga, C. R. S. & Zaagsma, J., Jun-1995, In: British Journal of Pharmacology. 115, 4, p. 665-671 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Scopus)

1994

Selectivity Profile of Some Recent Muscarinic Antagonists in Bovine and Guinea-Pig Trachea and Heart

Roffel, A. F., Hamstra, J. J., Elzinga, C. R. S. & Zaagsma, J., 1994, In: Archives internationales de pharmacodynamie et de therapie. 328, 1, p. 82-98 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

11 Citations (Scopus)

1993

Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M2-like receptors

Roffel, A. F., Elzinga, C. R. S. & Zaagsma, J., 7-Dec-1993, In: European Journal of Pharmacology. 250, 2, p. 267-279 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

28 Citations (Scopus)

Muscarinic M₂ receptors do not participate in the functional antagonism between methacholine and isoprenaline in guinea pig tracheal smooth muscle

Roffel, A. F., Meurs, H., Elzinga, C. R. S. & Zaagsma, J., 9-Nov-1993, In: European Journal of Pharmacology. 249, 2, p. 235-238 4 p.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

27 Citations (Scopus)

1991

HETEROGENEOUS RECEPTOR-BINDING OF CLASSICAL QUATERNARY MUSCARINIC ANTAGONISTS .2. MODULATION IN BOVINE BRAIN

ROFFEL, A., ENSING, K., ELZINGA, C., INTHOUT, W., VANTINTELEN, E., DEZEEUW, R. & ZAAGSMA, J., 1991, In: Archives internationales de pharmacodynamie et de therapie. 314, p. 105-121 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Scopus)

POSITIVE COOPERATIVE INTERACTION OF QUATERNARY ANTICHOLINERGICS WITH FUNCTIONAL MUSCARINIC RECEPTORS IN BOVINE TRACHEAL SMOOTH-MUSCLE

ROFFEL, A., ELZINGA, C., BELTMAN, W., VANTINTELEN, E. & ZAAGSMA, J., Mar-1991, In: Naunyn-Schmiedebergs Archives of Pharmacology. 343, 3, p. 252-259 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

1990

CHARACTERIZATION OF THE MUSCARINIC RECEPTOR SUBTYPE INVOLVED IN PHOSPHOINOSITIDE METABOLISM IN BOVINE TRACHEAL SMOOTH-MUSCLE

ROFFEL, A., MEURS, H., ELZINGA, C. & ZAAGSMA, J., Feb-1990, In: British Journal of Pharmacology. 99, 2, p. 293-296 4 p.

Research output: Contribution to journal › Article › Academic › peer-review

83 Citations (Scopus)

1989

ALLOSTERIC INTERACTIONS OF 3 MUSCARINE ANTAGONISTS AT BOVINE TRACHEAL SMOOTH-MUSCLE AND CARDIAC M2 RECEPTORS

ROFFEL, A., ELZINGA, C., MEURS, H. & ZAAGSMA, J., 7-Mar-1989, In: European journal of pharmacology-Molecular pharmacology section. 172, 1, p. 61-70 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

33 Citations (Scopus)

1988

EVIDENCE FOR A DIRECT RELATIONSHIP BETWEEN PHOSPHOINOSITIDE METABOLISM AND AIRWAY SMOOTH-MUSCLE CONTRACTION INDUCED BY MUSCARINIC AGONISTS

MEURS, H., ROFFEL, A., POSTEMA, J., ELZINGA, C., KAUFFMAN, H. & ZAAGSMA, J., 1-Nov-1988, In: European Journal of Pharmacology. 156, 2, p. 271-274 4 p.

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

55 Citations (Scopus)

MUSCARINIC M2 RECEPTORS IN BOVINE TRACHEAL SMOOTH-MUSCLE - DISCREPANCIES BETWEEN BINDING AND FUNCTION

ROFFEL, A., ELZINGA, C., VANAMSTERDAM, R., DEZEEUW, R. & ZAAGSMA, J., 9-Aug-1988, In: European Journal of Pharmacology. 153, 1, p. 73-82 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

133 Citations (Scopus)

Carolina Elzinga

Research output

Search results