Research output per year
Research output per year
Personal profile
Research interests
Single cell sequencing, genome instability, structural variations, ageing, stem cells, cancer, immunology
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A non-genetic switch triggers alternative telomere lengthening and cellular immortalization in ATRX deficient cells
Turkalo, T. K., Maffia, A., Schabort, J. J., Regalado, S. G., Bhakta, M., Blanchette, M., Spierings, D. C. J., Lansdorp, P. M. & Hockemeyer, D., Feb-2023, In: Nature Communications. 14, 1, 17 p., 939.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia
Rutten, M. G. S., Lei, Y., Hoogerland, J. H., Bloks, V. W., Yang, H., Bos, T., Krishnamurthy, K. A., Bleeker, A., Koster, M. H., Thomas, R. E., Wolters, J. C., van den Bos, H., Mithieux, G., Rajas, F., Mardinoglu, A., Spierings, D. C. J., de Bruin, A., van de Sluis, B. & Oosterveer, M. H., 21-Apr-2023, In: Cancer & Metabolism. 11, 11 p., 5.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Short-term molecular consequences of chromosome mis-segregation for genome stability
Garribba, L., De Feudis, G., Martis, V., Galli, M., Dumont, M., Eliezer, Y., Wardenaar, R., Ippolito, M. R., Iyer, D. R., Tijhuis, A. E., Spierings, D. C. J., Schubert, M., Taglietti, S., Soriani, C., Gemble, S., Basto, R., Rhind, N., Foijer, F., Ben-David, U., Fachinetti, D., & 2 others, 11-Mar-2023, In: Nature Communications. 14, 17 p., 1353.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure) -
Author Correction: Genetic instability from a single S phase after whole-genome duplication (Nature, (2022), 604, 7904, (146-151), 10.1038/s41586-022-04578-4)
Gemble, S., Wardenaar, R., Keuper, K., Srivastava, N., Nano, M., Macé, A. S., Tijhuis, A. E., Bernhard, S. V., Spierings, D. C. J., Simon, A., Goundiam, O., Hochegger, H., Piel, M., Foijer, F., Storchová, Z. & Basto, R., 18-Aug-2022, In: Nature. 608, p. E27Research output: Contribution to journal › Erratum
Open Access -
C/EBPβ isoform-specific regulation of migration and invasion in triple-negative breast cancer cells
Sterken, B. A., Ackermann, T., Müller, C., Zuidhof, H. R., Kortman, G., Hernandez-Segura, A., Broekhuis, M., Spierings, D., Guryev, V. & Calkhoven, C. F., Dec-2022, In: NPJ Breast Cancer. 8, 1, 13 p., 11.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)25 Downloads (Pure)
Activities
- 1 Academic presentation
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Dutch Hematology congress
Diana Spierings (Speaker)
24-Jan-2018 → 26-Jan-2018Activity: Talk and presentation › Academic presentation › Academic
Datasets
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Single cell whole genome sequencing of high hyperdiploid acute lymphoblastic leukemia
Woodward, E. (Contributor), Yang, M. (Contributor), Moura-Castro, L. H. (Contributor), van den Bos, H. (Contributor), Gunnarsson, R. (Contributor), Arvidsson, L. O. (Contributor), Spierings, D. (Contributor), Castor, A. (Contributor), Duployez, N. (Contributor), Zaliova, M. (Contributor), Zuna, J. (Contributor), Johansson, B. (Contributor), Foijer, F. (Contributor) & Paulsson, K. (Contributor), National Bioinformatics Infrastructure Sweden, 22-Feb-2022
DOI: 10.17044/scilifelab.19160954.v1, https://scilifelab.figshare.com/articles/dataset/Single_cell_whole_genome_sequencing_of_high_hyperdiploid_acute_lymphoblastic_leukemia/19160954/1
Dataset
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Data: Direct chromosome-length haplotyping by single-cell sequencing
Lansdorp, P. (Creator), Sanders, A. D. (Creator), van Wietmarschen, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Creator), Bevova, M. (Creator) & Guryev, V. (Creator), University of Groningen, 26-Nov-2016
DOI: 10.5281/zenodo.599901, https://zenodo.org/record/830278
Dataset
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Data from: Direct chromosome-length haplotyping by single-cell sequencing
Lansdorp, P. M. (Contributor), Sanders, A. D. (Contributor), Wietmarschen ,van, N. (Creator), Falconer, E. (Creator), Hills, M. (Creator), Spierings, D. (Contributor), Bevova, M. (Creator) & Guryev, V. (Contributor), ZENODO, 26-Nov-2016
Dataset
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Additional file 11 of InvertypeR: Bayesian inversion genotyping with Strand-seq data
Hanlon, V. (Contributor), Mattsson, C. (Contributor), Spierings, D. (Contributor), Guryev, V. (Contributor) & Lansdorp, P. M. (Contributor), figshare Academic Research System, 31-Jul-2021
DOI: 10.6084/m9.figshare.15087431.v1
Dataset
Press/Media
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Death receptors in normal and malignant tissues
14/03/2004
1 Media contribution
Press/Media: Expert Comment › Professional