Dianne Jansen

2025

Genome-wide meta-analysis associates donor-recipient non-HLA genetic mismatch with acute cellular rejection post-liver transplantation

TransplantLines Investigators, Nieuwenhuis, L. M., Li, Y., Loza, B.-L., Lambeck, A. J. A., Hu, S., Gacesa, R., Voskuil, M. D., Hepkema, B. G., Jansen, B. H., Blokzijl, H., Verkade, H.-J., van den Heuvel, M. C., Asrani, S., Testa, G., Klintmalm, G., Trotter, J., Olthoff, K. M., Shaked, A. & Keating, B. J. & 3 others, Weersma, R. K., Festen, E. A. M. & de Meijer, V. E., Jan-2025, In: Hepatology communications. 9, 1, 15 p., e0601.

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2024

Choice of DNA extraction method affects stool microbiome recovery and subsequent phenotypic association analyses

Fernández-Pato, A., Sinha, T., Gacesa, R., Andreu-Sánchez, S., Gois, M. F. B., Gelderloos-Arends, J., Jansen, D. B. H., Kruk, M., Jaeger, M., Joosten, L. A. B., Netea, M. G., Weersma, R. K., Wijmenga, C., Harmsen, H. J. M., Fu, J., Zhernakova, A. & Kurilshikov, A., 16-Feb-2024, In: Scientific Reports. 14, 11 p., 3911.

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9 Citations (Scopus)

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Limited predictive value of the gut microbiome and metabolome for response to biological therapy in inflammatory bowel disease

Prins, F. M., Hidding, I. J., Klaassen, M. A. Y., Collij, V., Schultheiss, J. P. D., Uniken Venema, W. T. C., Bangma, A., Aardema, J. B., Jansen, B. H., Mares, W. G. N., Witteman, B. J. M., Festen, E. A. M., Dijkstra, G., Visschedijk, M. C., Fidder, H. H., Vich Vila, A., Oldenburg, B., Gacesa, R. & Weersma, R. K., 2024, In: Gut Microbes. 16, 1, 18 p., 2391505.

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2 Citations (Scopus)

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Mucosal host-microbe interactions associate with clinical phenotypes in inflammatory bowel disease

Hu, S., Bourgonje, A. R., Gacesa, R., Jansen, B. H., Björk, J. R., Bangma, A., Hidding, I. J., van Dullemen, H. M., Visschedijk, M. C., Faber, K. N., Dijkstra, G., Harmsen, H. J. M., Festen, E. A. M., Vich Vila, A., Spekhorst, L. M. & Weersma, R. K., 17-Feb-2024, In: Nature Communications. 15, 14 p., 1470.

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17 Citations (Scopus)

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The gut microbiome across the cardiovascular risk spectrum

Prins, F. M., Collij, V., Groot, H. E., Björk, J. R., Swarte, J. C., Andreu-Sánchez, S., Jansen, B. H., Fu, J., Harmsen, H. J. M., Zhernakova, A., Lipsic, E., van der Harst, P., Weersma, R. K. & Gacesa, R., Jun-2024, In: European Journal of Preventive Cardiology. 31, 8, p. 935–944 26 p.

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9 Citations (Scopus)

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The gut microbiome in end-stage lung disease and lung transplantation

TransplantLines Investigators, Zhang, S., Swarte, J. C., Gacesa, R., Knobbe, T. J., Kremer, D., Jansen, B. H., de Borst, M. H., Harmsen, H. J. M., Erasmus, M. E., Verschuuren, E. A. M., Bakker, S. J. L., Gan, C. T., Weersma, R. K. & Björk, J. R., Jun-2024, In: Msystems. 9, 6, 15 p., e0131223.

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2 Citations (Scopus)

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2023

Faecal metabolome and its determinants in inflammatory bowel disease

Vich Vila, A., Hu, S., Andreu-Sánchez, S., Collij, V., Jansen, B. H., Augustijn, H. E., Bolte, L. A., Ruigrok, R. A. A. A., Abu-Ali, G., Giallourakis, C., Schneider, J., Parkinson, J., Al-Garawi, A., Zhernakova, A., Gacesa, R., Fu, J. & Weersma, R. K., Aug-2023, In: Gut. 72, 8, p. 1472-1485 14 p.

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65 Citations (Scopus)

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Health-related quality of life is linked to the gut microbiome in kidney transplant recipients

TransplantLines Investigators, Swarte, J. C., Knobbe, T. J., Björk, J. R., Gacesa, R., Nieuwenhuis, L. M., Zhang, S., Vila, A. V., Kremer, D., Douwes, R. M., Post, A., Quint, E. E., Pol, R. A., Jansen, B. H., Londen, M. V., Borst, M. D., Meijer, V. E. D., Blokzijl, H., Berger, S. & Festen, E. A. M. & 5 others, Zhernakova, A., Fu, J., Harmsen, H. J. M., Bakker, S. & Weersma, R. K., 2-Dec-2023, In: Nature Communications. 14, 1, 11 p., 7968.

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10 Citations (Scopus)

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Unsuitability of the Oxidation-Reduction Potential Measurement for the Quantification of Fecal Redox Status in Inflammatory Bowel Disease

Geertsema, S., Jansen, B. H., van Goor, H., Dijkstra, G., Faber, K. N. & Bourgonje, A. R., 21-Nov-2023, In: Biomedicines. 11, 12, 11 p., 3107.

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1 Citation (Scopus)

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2022

Environmental factors shaping the gut microbiome in a Dutch population

Gacesa, R., Kurilshikov, A., Vich Vila, A., Sinha, T., Klaassen, M. A. Y., Bolte, L. A., Andreu-Sánchez, S., Chen, L., Collij, V., Hu, S., Dekens, J. A. M., Lenters, V. C., Björk, J. R., Swarte, J. C., Swertz, M. A., Jansen, B. H., Gelderloos-Arends, J., Jankipersadsing, S., Hofker, M. & Vermeulen, R. C. H. & 6 others, Sanna, S., Harmsen, H. J. M., Wijmenga, C., Fu, J., Zhernakova, A. & Weersma, R. K., 2022, In: Nature. p. 732–739 25 p.

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389 Citations (Scopus)

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Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation

Swarte, J. C., Li, Y., Hu, S., Björk, J. R., Gacesa, R., Vich Vila, A., Douwes, R. M., Collij, V., Kurilshikov, A., Post, A., Klaassen, M. A. Y., Eisenga, M. F., Gomes-Neto, A. W., Kremer, D., Jansen, B. H., Knobbe, T. J., Berger, S. P., Sanders, J.-S. F., Heiner-Fokkema, M. R. & Porte, R. J. & 10 others, Cuperus, F. J. C., de Meijer, V. E., Wijmenga, C., Festen, E. A. M., Zhernakova, A., Fu, J., Harmsen, H. J. M., Blokzijl, H., Bakker, S. J. L. & Weersma, R. K., 31-Aug-2022, In: Science Translational Medicine. 14, 660, 15 p., eabn7566.

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51 Citations (Scopus)

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HIF1α-Dependent Induction of TFRC by a Combination of Intestinal Inflammation and Systemic Iron Deficiency in Inflammatory Bowel Disease

Fagundes, R. R., Bourgonje, A. R., Hu, S., Barbieri, R., Jansen, B. H., Sinnema, N., Blokzijl, T., Taylor, C. T., Weersma, R. K., Faber, K. N. & Dijkstra, G., 8-Jun-2022, In: Frontiers in Physiology. 13, 16 p., 889091.

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10 Citations (Scopus)

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2021

Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome-wide association study

Li, Y., Nieuwenhuis, L. M., Voskuil, M. D., Gacesa, R., Hu, S., Jansen, B. H., Uniken Venema, W. T., Hepkema, B. G., Blokzijl, H., Verkade, H. J., Lisman, T., Weersma, R. K., Porte, R. J., Festen, E. A. M. & de Meijer, V. E., Sept-2021, In: American Journal of Transplantation. 21, 9, p. 3133-3147 15 p.

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6 Citations (Scopus)

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Exome sequencing in patient-parent trios suggests new candidate genes for early-onset primary sclerosing cholangitis

Haisma, S.-M., Weersma, R. K., Joosse, M. E., de Koning, B. A., de Meij, T., Koot, B. G., Wolters, V., Norbruis, O., Daly, M. J., Stevens, C., Xavier, R. J., Koskela, J., Rivas, M. A., Visschedijk, M. C., Verkade, H. J., Barbieri, R., Jansen, D. B., Festen, E. A., van Rheenen, P. F. & van Diemen, C. C., 11-Mar-2021, In: Liver International. 14 p.

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7 Citations (Scopus)

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Genetic risk scores identify genetic aetiology of inflammatory bowel disease phenotypes

Parelsnoer Institute and the Dutch Initiative on Crohn and Colitis, Voskuil, M. D., Spekhorst, L. M., van der Sloot, K. W. J., Jansen, B. H., Dijkstra, G., van der Woude, C. J., Hoentjen, F., Pierik, M. J., van der Meulen, A. E., de Boer, N. K. H., Löwenberg, M., Oldenbrug, B., Festen, E. A. M. & Weersma, R. K., Jun-2021, In: Journal of Crohn's and Colitis. 15, 6, p. 930-937 8 p.

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7 Citations (Scopus)

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Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease

Hu, S., Uniken Venema, W. T., Westra, H.-J., Vich Vila, A., Barbieri, R., Voskuil, M. D., Blokzijl, T., Jansen, B. H., Li, Y., Daly, M. J., Xavier, R. J., Dijkstra, G., Festen, E. A. & Weersma, R. K., 18-Feb-2021, In: Nature Communications. 12, 1, 10 p., 1122.

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28 Citations (Scopus)

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The composition and metabolic potential of the human small intestinal microbiota within the context of inflammatory bowel disease

Ruigrok, R. A. A. A., Collij, V., Sureda, P., Klaassen, M. A. Y., Bolte, L. A., Jansen, B. H., Voskuil, M. D., Fu, J., Wijmenga, C., Zhernakova, A., Weersma, R. K. & Vich Vila, A., Aug-2021, In: Journal of Crohn's and Colitis. 15, 8, p. 1326-1338 13 p.

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24 Citations (Scopus)

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2020

Pirfenidone Inhibits Cell Proliferation and Collagen I Production of Primary Human Intestinal Fibroblasts

Cui, Y., Zhang, M., Leng, C., Blokzijl, T., Jansen, B. H., Dijkstra, G. & Faber, K. N., 22-Mar-2020, In: Cells. 9, 3, 16 p., 775.

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41 Citations (Scopus)

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Riboflavin Supplementation in Patients with Crohn's Disease [the RISE-UP study]

von Martels, J. Z. H., Bourgonje, A. R., Klaassen, M. A. Y., Alkhalifah, H. A. A., Sadaghian Sadabad, M., Vich Vila, A., Gacesa, R., Gabriëls, R. Y., Steinert, R. E., Jansen, B. H., Bulthuis, M. L. C., van Dullemen, H. M., Visschedijk, M. C., Festen, E. A. M., Weersma, R. K., de Vos, P., van Goor, H., Faber, K. N., Harmsen, H. J. M. & Dijkstra, G., May-2020, In: Journal of Crohn's and Colitis. 14, 5, p. 595-607 13 p.

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80 Citations (Scopus)

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2019

A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease

Bourgonje, A. R., von Martels, J. Z. H., Gabriëls, R. Y., Blokzijl, T., Buist-Homan, M., Heegsma, J., Jansen, B. H., Dullemen, van, H. M., Festen, E. A. M., ter Steege, R. W. F., Visschedijk, M. C., Weersma, R. K., de Vos, P., Faber, K. N. & Dijkstra, G., 5-Nov-2019, In: Frontiers in Medicine. 6, p. 251 13 p., 251.

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47 Citations (Scopus)

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Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets

Uniken Venema, W. T., Voskuil, M. D., Vich Vila, A., van der Vries, G., Jansen, B. H., Jabri, B., Faber, K. N., Dijkstra, G., Xavier, R. J., Wijmenga, C., Graham, D. B., Weersma, R. K. & Festen, E. A., Feb-2019, In: Gastroenterology. 156, 3, p. 812-+ 26 p.

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45 Citations (Scopus)

674 Downloads (Pure)

2018

Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn's Disease

Visschedijk, M. C., Spekhorst, L. M., Cheng, S.-C., van Loo, E. S., Jansen, B. H. D., Blokzijl, T., Kil, H., de Jong, D. J., Pierik, M., Maljaars, J. P. W. J., van der Woude, C. J., van Bodegraven, A. A., Oldenburg, B., Löwenberg, M., Nieuwenhuijs, V. B., Imhann, F., van Sommeren, S., Alberts, R., Xavier, R. J. & Dijkstra, G. & 4 others, Faber, K. N., Aldaz, C. M., Weersma, R. K. & Festen, E. A. M., May-2018, In: Journal of Crohn's and Colitis. 12, 5, p. 582-588 7 p.

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Dianne Jansen

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