Personal profile
External positions
Honorary Associate Professor, University of Exeter
2014 → 2017
Visiting Professor, Univ Alberta, University of Alberta
1-Oct-2013 → 31-Dec-2013
Visiting Professor, Harbin Med Univ, Harbin Medical University, Affiliated Hosp 1, Dept Hematol
2012 → …
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 7 Affordable and Clean Energy -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 12 Responsible Consumption and Production
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Collaborations and top research areas from the last five years
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A Luminescence-Based Method for In Vitro Screening of Immunomodulatory Checkpoints and Therapeutics
Álvarez Freile, J. & Bremer, E., 2025, Cancer Immunosurveillance: Methods and Protocols. López-Soto, A. & Folgueras, A. R. (eds.). 2 ed. Humana Press, p. 245-257 13 p. (Methods in Molecular Biology; vol. 2930).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
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Atezolizumab Consolidation in Patients with High Risk Diffuse Large B-cell Lymphoma in Complete Remission after R-CHOP
Nijland, M., Issa, D. E., Bult, J. A. A., Deeren, D., Velders, G. A., Nijziel, M. R., Sandberg, Y., Vergote, V. K., Oosterveld, M., Fijnheer, R., Brouwer, R., Boersma, R., Wu, K., Nieuwenhuizen, L., Vermaat, J. S., van Kampen, R. J. W., Terpstra, W. E., Snauwaert, S., van der Poel, M. W. & de Jongh, E. & 22 others, , 10-Jul-2025, In: Blood Advances. 9, 14, p. 3530–3539 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)25 Downloads (Pure) -
Ensuring CAR-T Cell Quality: In-Process Controls and Quality Control Testing
D’Amore, M. L., Gareb, B., Quintarelli, C. & Bremer, E., 12-Jun-2025, The EU CAR-T Handbook. Aljurf, M., Bonini, C., Chabannon, C., Delgado, J., Dreyling, M., Kuball, J., Ruggeri, A., Subklewe, M. & Sureda, A. (eds.). 2 ed. European Hematology Association (EHA) / European Society for Blood and Marrow Transplantation (EBMT)Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
Open Access -
Galectin-9 treatment is cytotoxic for B cell lymphoma by disrupting autophagy
Koll, L., Lourens, H. J., Marsman, G., de Haan, S., Niki, T., Huls, G. A., Bremer, E. & Wiersma, V. R., 26-Jun-2025, In: Frontiers in Pharmacology. 16, 13 p., 1601235.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)19 Downloads (Pure) -
High expression of signal regulatory protein beta 2 marks a favourable prognostic AML subgroup and associates with increased sensitivity to phagocytosis
Visser, N., van der Meer, N. K., He, Y., Huls, G., Schuringa, J. J. & Bremer, E., 25-Jun-2025, In: Immunologic research. 73, 1, 7 p., 98.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile28 Downloads (Pure)
Activities
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Jimena Alvarez Freile; Navigating the path of cancer immunotherapeutics. Novel targets and innovative development tools.
Laman, J. D. (Member of PhD Examining Committee), Bremer, E. (Supervisor), Huls, G. (Supervisor), de Bruyn, M. (Co-supervisor) & Dähne, L. (Co-supervisor)
11-Mar-2024Activity: Examination, teaching and supervision › Supervision and examination of PhD students of the UG › Academic
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Yusheng Lin; Towards personalized cancer management: diagnosis and (immuno)therapy
Bremer, E. (Supervisor), Zhang, H. (Co-supervisor) & Huls, G. (Co-supervisor)
27-Nov-2023Activity: Examination, teaching and supervision › Supervision and examination of PhD students of the UG › Academic
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R. Bouwstra; Innate immune checkpoint inhibitors for treatment of diffuse large B-cell lymphoma
Laman, J. D. (Member of PhD Examining Committee), Bremer, E. (Supervisor), Huls, G. (Supervisor) & van Meerten, T. (Co-supervisor)
21-Sept-2022Activity: Examination, teaching and supervision › Supervision and examination of PhD students of the UG › Academic
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The 62nd American Society of Hematology (ASH)
Bremer, E. (Invited speaker)
5-Dec-2020Activity: Talk and presentation › Academic presentation › Academic
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Cancers (Journal)
Bremer, E. (Editorial board member)
2020 → …Activity: Peer-review and editorial work › Editorial work › Academic
Datasets
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The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
Wiersma, V. R. (Creator), de Bruyn, M. (Contributor), Wei, Y. (Contributor), van Ginkel, R. J. (Contributor), Hirashima, M. (Contributor), Niki, T. (Creator), Nishi, N. (Creator), Zhou, J. (Creator), Pouwels, S. D. (Creator), Samplonius, D. F. (Creator), Nijman, H. W. (Creator), Eggleton, P. (Creator), Helfrich, W. (Contributor) & Bremer, E. (Creator), figshare, 3-Aug-2015
DOI: 10.6084/m9.figshare.1452909.v1, https://figshare.com/articles/The_epithelial_polarity_regulator_LGALS9_galectin_9_induces_fatal_frustrated_autophagy_in_KRAS_mutant_colon_carcinoma_that_depends_on_elevated_basal_autophagic_flux/1452909/1
Dataset
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The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
Wiersma, V. R. (Creator), de Bruyn, M. (Contributor), Wei, Y. (Contributor), van Ginkel, R. J. (Contributor), Hirashima, M. (Contributor), Niki, T. (Creator), Nishi, N. (Creator), Zhou, J. (Creator), Pouwels, S. D. (Creator), Samplonius, D. F. (Creator), Nijman, H. W. (Creator), Eggleton, P. (Creator), Helfrich, W. (Creator) & Bremer, E. (Creator), figshare, 8-Oct-2015
DOI: 10.6084/m9.figshare.1452909.v2
Dataset
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The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
Wiersma, V. R. (Creator), de Bruyn, M. (Contributor), Wei, Y. (Contributor), van Ginkel, R. J. (Contributor), Hirashima, M. (Contributor), Niki, T. (Creator), Nishi, N. (Creator), Zhou, J. (Creator), Pouwels, S. D. (Creator), Samplonius, D. F. (Creator), Nijman, H. W. (Creator), Eggleton, P. (Creator), Helfrich, W. (Creator) & Bremer, E. (Creator), figshare, 8-Oct-2015
DOI: 10.6084/m9.figshare.1452909.v6
Dataset
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Additional file 1 of DSP107 combines inhibition of CD47/SIRPα axis with activation of 4-1BB to trigger anticancer immunity
Cendrowicz, E. (Contributor), Jacob, L. (Contributor), Greenwald, S. (Creator), Tamir, A. (Creator), Pecker, I. (Creator), Tabakman, R. (Creator), Ghantous, L. (Creator), Tamir, L. (Creator), Kahn, R. (Creator), Avichzer, J. (Creator), Aronin, A. (Creator), Amsili, S. (Creator), Zorde-Khvalevsky, E. (Creator), Gozlan, Y. (Creator), Vlaming, M. (Contributor), Huls, G. (Creator), van Meerten, T. (Contributor), Dranitzki, M. E. (Creator), Foley-Comer, A. (Creator), Pereg, Y. (Creator), Peled, A. (Creator), Chajut, A. (Creator) & Bremer, E. (Creator), figshare, 14-Mar-2022
DOI: 10.6084/m9.figshare.19359964, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_DSP107_combines_inhibition_of_CD47_SIRP_axis_with_activation_of_4-1BB_to_trigger_anticancer_immunity/19359964
Dataset
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The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
Wiersma, V. R. (Creator), de Bruyn, M. (Contributor), Wei, Y. (Contributor), van Ginkel, R. J. (Contributor), Hirashima, M. (Contributor), Niki, T. (Creator), Nishi, N. (Creator), Zhou, J. (Creator), Pouwels, S. D. (Creator), Samplonius, D. F. (Creator), Nijman, H. W. (Creator), Eggleton, P. (Creator) & Bremer, E. (Creator), figshare, 8-Oct-2015
DOI: 10.6084/m9.figshare.1452909.v4
Dataset
Press/Media
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Kankerpatiënten gaan in het UMCG worden behandeld met zelfontwikkelde CAR-T-cellen
21/07/2025 → 22/07/2025
1 item of Media coverage, 1 Media contribution
Press/Media: Expert Comment › Popular
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Groningse CAR-T-celtherapie krijgt KWF-subsidie
29/01/2024
1 item of Media coverage
Press/Media: Expert Comment › Popular
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2,6 miljoen subsidie voor revolutionair oncologie onderzoek
04/08/2022
1 Media contribution
Press/Media: Other › Popular
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UMCG ontvangt grote EU-subsidie voor onderzoek naar nieuwe immuuntherapie bij kanker
02/08/2022
3 Media contributions
Press/Media: Public Engagement Activities › Popular
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Miljoenensubsidie voor UMCG-onderzoek naar therapie voor uitbehandelde kankerpatiënten
02/08/2022
1 Media contribution
Press/Media: Expert Comment › Popular
Prizes
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Alexander von Humboldt Fellowship
Bremer, E. (Recipient), 2007
Prize: Fellowship awarded competitively › Academic
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