Hans den Boer

2020

Ovariectomy-induced depressive-like behavior and brain glucose metabolism changes in female rats are not affected by chronic mild stress

Khayum, M. A., Moraga-Amaro, R., Buwalda, B., Koole, M., den Boer, J. A., Dierckx, R. A. J. O., Doorduin, J. & de Vries, E. F. J., May-2020, In: Psychoneuroendocrinology. 115, 9 p., 104610.

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26 Citations (Scopus)

243 Downloads (Pure)

2019

Major depressive disorder is associated with changes in a cluster of serum and urine biomarkers

van Buel, E. M., Meddens, M. J. M., Arnoldussen, E. A., van den Heuvel, E. R., Bohlmeijer, W. C., den Boer, J. A., Muller Kobold, A., Boonman-de Winter, L. J. M., van Rumpt, D., Timmers, L. F. J., Veerman, M. F. A., Kamphuis, J. S., Gladkevich, A. V., Schoevers, R. A., Luiten, P. G. M., Eisel, U. L. M., Bosker, F. J. & Klein, H. C., Oct-2019, In: Journal of Psychosomatic Research. 125, 109796.

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13 Citations (Scopus)

91 Downloads (Pure)

2016

The Psychobiology of Authentic and Simulated Dissociative Personality States: The Full Monty

Reinders, A. A. T. S., Willemsen, A., Vissia, E. M., Vos, H. P. J., den Boer, J. A. & Nijenhuis, E. R. S., Jun-2016, In: JOURNAL OF NERVOUS AND MENTAL DISEASE. 204, 6, p. 445-457 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

34 Citations (Scopus)

2015

In vivo imaging of brain androgen receptors in rats: a [(18)F]FDHT PET study

Khayum, M. A., Doorduin, J., Farinha Antunes, I., Kwizera, C., Zijlma, R., den Boer, J. A., Dierckx, R. A. J. O. & de Vries, E. F. J., Jun-2015, In: Nuclear Medicine and Biology. 42, 6, p. 561-569 9 p.

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10 Citations (Scopus)

151 Downloads (Pure)

Serotonin-2C antagonism augments the effect of citalopram on serotonin and dopamine levels in the ventral tegmental area and nucleus accumbens

Visser, A. K. D., Kleijn, J., van Faassen, M. H. J. R., Dremencov, E., Flik, G., Kema, I. P., Den Boer, J. A., van Waarde, A., Dierckx, R. A. J. O. & Bosker, F. J., Feb-2015, In: Neurochemistry International. 81, p. 10-15 6 p.

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10 Citations (Scopus)

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2014

Acute social defeat does not alter cerebral 5-HT2A receptor binding in male Wistar rats

Visser, A. K. D., Meerlo, P., Ettrup, A., Knudsen, G. M., Bosker, F. J., den Boer, J. A., Dierckx, R. A. J. O. & van Waarde, A., 2014, In: Synapse. 68, 9, p. 379-386

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

Analysis of cognition, motor performance and anxiety in young and aged tumor necrosis factor alpha receptor 1 and 2 deficient mice

Naude, P. J. W., Dobos, N., van der Meer, D., Mulder, C., Pawironadi, K. G. D., den Boer, J. A., van der Zee, E. A., Luiten, P. & Eisel, U. L. M., 1-Jan-2014, In: Behavioural Brain Research. 258, p. 43-51 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

35 Citations (Scopus)

Cost-effectiveness of CBT, SSRI, and CBT+SSRI in the treatment for panic disorder

van Apeldoorn, F. J., Stant, A. D., van Hout, W. J. P. J., Mersch, P. P. A. & den Boer, J. A., Apr-2014, In: Acta Psychiatrica Scandinavica. 129, 4, p. 286-295 10 p.

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16 Citations (Scopus)

Opposite brain emotion-regulation patterns in identity states of dissociative identity disorder: A PET study and neurobiological model

Reinders, A. A. T. S., Willemsen, A. T. M., den Boer, J. A., Vos, H. P. J., Veltman, D. J. & Loewenstein, R. J., 30-Sept-2014, In: Psychiatry research: Neuroimaging. 223, 3, p. 236-243 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

60 Citations (Scopus)

Sex-specific associations between Neutrophil Gelatinase-Associated Lipocalin (NGAL) and cognitive domains in late-life depression

Naude, P. J. W., den Boer, J. A., Comijs, H. C., Bosker, F. J., Zuidersma, M., Groenewold, N. A., De Deyn, P. P., Luiten, P. G. M., Eisel, U. L. M. & Oude Voshaar, R. C., Oct-2014, In: Psychoneuroendocrinology. 48, p. 169-177 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

24 Citations (Scopus)

2013

ABCB1 gene variants influence tolerance to selective serotonin reuptake inhibitors in a large sample of Dutch cases with major depressive disorder

de Klerk, O. L., Nolte, I. M., Bet, P. M., Bosker, F. J., Snieder, H., den Boer, J. A., Bruggeman, R., Hoogendijk, W. J. & Penninx, B. W., Aug-2013, In: Pharmacogenomics journal. 13, 4, p. 349-353 5 p.

Research output: Contribution to journal › Article › Academic › peer-review

49 Citations (Scopus)

Analysis of 5-HT2A Receptor Binding with [C-11]MDL 100907 in Rats: Optimization of Kinetic Modeling

Visser, A. K. D., De Vries, E. F. J., K. Ramakrishnan, N., Willemsen, A. T. M., Bosker, F. J., den Boer, J. A., Dierckx, R. A. J. O. & van Waarde, A., Dec-2013, In: Molecular Imaging and Biology. 15, 6, p. 730-738 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

6 Citations (Scopus)

Antiaggressive activity of central oxytocin in male rats

Calcagnoli, F., de Boer, S. F., Althaus, M., den Boer, J. A. & Koolhaas, J. M., Oct-2013, In: Psychopharmacology. 229, 4, p. 639-651 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

81 Citations (Scopus)

Chronic stress-induced changes in the rat brain: Role of sex differences and effects of long-term tianeptine treatment

Kuipers, S. D., Trentani, A., van der Zee, E. A. & den Boer, J. A., Dec-2013, In: Neuropharmacology. 75, p. 426-436 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

Neutrophil gelatinase-associated lipocalin: A novel inflammatory marker associated with late-life depression

Naude, P. J. W., Eisel, U. L. M., Comijs, H. C., Groenewold, N. A., De Deyn, P. P., Bosker, F. J., Luiten, P. G. M., den Boer, J. A. & Voshaar, R. C. O., Nov-2013, In: Journal of Psychosomatic Research. 75, 5, p. 444-450 7 p.

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74 Citations (Scopus)

10 Downloads (Pure)

Rate of improvement during and across three treatments for panic disorder with or without agoraphobia: Cognitive behavioral therapy, selective serotonin reuptake inhibitor or both combined

Van Apeldoorn, F. J., Van Hout, W. J. P. J., Timmerman, M. E., Mersch, P. P. A. & den Boer, J. A., 5-Sept-2013, In: Journal of Affective Disorders. 150, 2, p. 313-319 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

18 Citations (Scopus)

Reduced spontaneous but relatively normal deliberate vicarious representations in psychopathy

Meffert, H., Gazzola, V., den Boer, J. A., Bartels, A. A. J. & Keysers, C., Aug-2013, In: Brain. 136, p. 2550-2562 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

235 Citations (Scopus)

2012

Bilateral Sensory Abnormalities in Patients with Unilateral Neuropathic Pain; A Quantitative Sensory Testing (QST) Study

Konopka, K.-H., Harbers, M., Houghton, A., Kortekaas, R., van Vliet, A., Timmerman, W., den Boer, J. A., Struys, M. M. R. F. & van Wijhe, M., 22-May-2012, In: PLoS ONE. 7, 5, 13 p., e37524.

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67 Citations (Scopus)

269 Downloads (Pure)

Comparison of brain and blood gene expression in an animal model of negative symptoms in schizophrenia

Bosker, F. J., Gladkevich, A. V., Pietersen, C. Y., Kooi, K. A., Bakker, P. L., Gerbens, F., den Boer, J. A., Korf, J. & te Meerman, G., 7-Aug-2012, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 38, 2, p. 142-148 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Cost-Effectiveness of Escitalopram in Major Depressive Disorder in the Dutch Health Care Setting

Nuijten, M. J. C., Brignone, M., Marteau, F., den Boer, J. A. & Hoencamp, E., Jun-2012, In: Clinical Therapeutics. 34, 6, p. 1364-1378 15 p.

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10 Citations (Scopus)

Despite higher glucocorticoid levels and stress responses in female rats, both sexes exhibit similar stress-induced changes in hippocampal neurogenesis

Hulshof, H. J., Novati, A., Luiten, P. G. M., den Boer, J. A. & Meerlo, P., 1-Oct-2012, In: Behavioral Brain Research. 234, 2, p. 357-364 8 p.

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16 Citations (Scopus)

35 Downloads (Pure)

Fact or Factitious? A Psychobiological Study of Authentic and Simulated Dissociative Identity States

Reinders, A. A. T. S., Willemsen, A. T. M., Vos, H. P. J., den Boer, J. A. & Nijenhuis, E. R. S., 29-Jun-2012, In: PLoS ONE. 7, 6, 17 p., e39279.

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73 Citations (Scopus)

346 Downloads (Pure)

Functional Magnetic Resonance Imaging Correlates of Emotional Word Encoding and Recognition in Depression and Anxiety Disorders

van Tol, M.-J., Demenescu, L. R., van der Wee, N. J. A., Kortekaas, R., Nielen, M. M. A., Den Boer, J. A., Renken, R. J., van Buchem, M. A., Zitman, F. G., Aleman, A. & Veltman, D. J., 1-Apr-2012, In: Biological Psychiatry. 71, 7, p. 593-602 10 p.

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78 Citations (Scopus)

Lipocalin 2: Novel component of proinflammatory signaling in Alzheimer's disease

Naudé, P. J. W., Nyakas, C., Eiden, L. E., Ait-Ali, D., Heide, R. V. D., Engelborghs, S., Luiten, P. G. M., De Deyn, P. P., den Boer, J. A. & Eisel, U. L. M., Jul-2012, In: The FASEB Journal. 26, 7, p. 2811-2823 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

160 Citations (Scopus)

Somatosensory Profiles but Not Numbers of Somatosensory Abnormalities of Neuropathic Pain Patients Correspond with Neuropathic Pain Grading

Konopka, K.-H., Harbers, M., Houghton, A., Kortekaas, R., van Vliet, A., Timmerman, W., den Boer, J. A., Struys, M. M. R. F. & van Wijhe, M., 22-Aug-2012, In: PLoS ONE. 7, 8, 11 p., e43526.

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12 Citations (Scopus)

235 Downloads (Pure)

The role of indoleamine 2,3-dioxygenase in a mouse model of neuroinflammation-induced depression

Dobos, N., de Vries, E. F. J., Kema, I. P., Patas, K., Prins, M., Nijholt, I. M., Dierckx, R. A., Korf, J., den Boer, J. A., Luiten, P. G. M. & Eisel, U. L. M., 2012, In: Journal of Alzheimer’s Disease. 28, 4, p. 905-915 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

101 Citations (Scopus)

247 Downloads (Pure)

2011

Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress

Dagyte, G., Crescente, I., Postema, F., Seguin, L., Gabriel, C., Mocaer, E., den Boer, J. A. & Koolhaas, J. M., 17-Mar-2011, In: Behavioral Brain Research. 218, 1, p. 121-128 8 p.

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68 Citations (Scopus)

351 Downloads (Pure)

Chronic stress and antidepressant agomelatine induce region-specific changes in synapsin I expression in the rat brain

Dagyte, G., Luiten, P. G., de Jager, T., Gabriel, C., Mocaer, E., den Boer, J. A. & van der Zee, E. A., Oct-2011, In: Journal of Neuroscience Research. 89, 10, p. 1646-1657 12 p.

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32 Citations (Scopus)

45 Downloads (Pure)

Dysfunctional beliefs in the process of change of cognitive treatment in obsessive compulsive checkers

Polman, A., Bouman, T. K., van Geert, P. L. C., de Jong, P. J. & den Boer, J. A., 2011, In: Clinical psychology & psychotherapy. 18, 3, p. 256-273 18 p.

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Latent class analysis of the Yale-Brown Obsessive-Compulsive Scale symptoms in obsessive-compulsive disorder

Delucchi, K. L., Katerberg, H., Stewart, S. E., Denys, D. A. J. P., Lochner, C., Stack, D. E., den Boer, J. A., van Balkom, A. J. L. M., Jenike, M. A., Stein, D. J., Cath, D. C. & Mathews, C. A., 2011, In: Comprehensive Psychiatry. 52, 3, p. 334-341 8 p.

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14 Citations (Scopus)

Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats

Hulshof, H. J., Novati, A., Sgoifo, A., Luiten, P. G. M., den Boer, J. A. & Meerlo, P., 2011, In: Behavioral Brain Research. 216, p. 552-560

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147 Citations (Scopus)

26 Downloads (Pure)

Neural correlates of perception of emotional facial expressions in out-patients with mild-to-moderate depression and anxiety. A multicenter fMRI study

Demenescu, L. R., Renken, R., Kortekaas, R., van Tol, M.-J., Marsman, J. B. C., van Buchem, M. A., van der Wee, N. J. A., Veltman, D. J., den Boer, J. & Aleman, A., Nov-2011, In: Psychological Medicine. 41, 11, p. 2253-2264 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

63 Citations (Scopus)

The role of p-glycoprotein in psychiatric disorders: a reliable guard of the brain?

De Klerk, O. L., Bosker, F. J., Luurtsema, G., Nolte, I. M., Dierckx, R., Den Boer, J. A. & Potschka, H., 1-Sept-2011, In: Central Nervous System Agents in Medicinal Chemistry. 11, 3, p. 197-209 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

11 Citations (Scopus)

2010

A randomized trial of cognitive-behavioral therapy or selective serotonin reuptake inhibitor or both combined for panic disorder with or without agoraphobia: Treatment results through 1-year follow-up

van Apeldoorn, F. J., Timmerman, M. E., Mersch, P. P. A., van Hout, W. J. P. J., Visser, S., van Dyck, R. & den Boer, J. A., May-2010, In: Journal of Clinical Psychiatry. 71, 5, p. 574-586 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

27 Citations (Scopus)

Auditory Hallucinations in Schizophrenia Are Associated with Reduced Functional Connectivity of the Temporo-Parietal Area

Vercammen, A., Knegtering, H., den Boer, J. A., Liemburg, E. J. & Aleman, A., 15-May-2010, In: Biological Psychiatry. 67, 10, p. 912-918 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

226 Citations (Scopus)

Biochemical and behavioral effects of long-term citalopram administration and discontinuation in rats Role of serotonin synthesis

Bosker, F. J., Tanke, M. A. C., Jongsma, M. E., Cremers, T. I. F. H., Jagtman, E., Pietersen, C. Y., van der Hart, M. G. C., Gladkevich, A. V., Kema, I. P., Westerink, B. H. C., Korf, J. & den Boer, J. A., Dec-2010, In: Neurochemistry International. 57, 8, p. 948-957 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

26 Citations (Scopus)

Chronic stress and antidepressant treatment have opposite effects on P-glycoprotein at the blood-brain barrier: an experimental PET study in rats

De Klerk, O. L., Bosker, F. J., Willemsen, A. T. M., Van Waarde, A., Visser, A. K. D., de Jager, T., Dagyte, G., Den Boer, J. A., Dierckx, R. A. & Meerlo, P., 2010, In: Journal of Psychopharmacology. 24, 8, p. 1237-1242

Research output: Contribution to journal › Article › Academic › peer-review

33 Citations (Scopus)

Functional connectivity of the temporo-parietal region in schizophrenia: Effects of rTMS treatment of auditory hallucinations

Vercammen, A., Knegtering, H., Liemburg, E. J., den Boer, J. A. & Aleman, A., Aug-2010, In: Journal of Psychiatric Research. 44, 11, p. 725-731 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

93 Citations (Scopus)

Impaired Attribution of Emotion to Facial Expressions in Anxiety and Major Depression

Demenescu, L. R., Kortekaas, R., den Boer, J. A. & Aleman, A., 1-Dec-2010, In: PLoS ONE. 5, 12, 5 p., 15058.

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211 Citations (Scopus)

336 Downloads (Pure)

Manifesto for a European Anxiety Disorders Research Network

Baldwin, D. S., Allgulander, C., Altamura, A. C., Angst, J., Bandelow, B., den Boer, J., Boyer, P., Davies, S., dell'Osso, B., Eriksson, E., Fineberg, N., Fredrikson, M., Herran, A., Maron, E., Metspalu, A., Nutt, D., van der Wee, N., Luis Vazquez-Barquero, J. & Zohar, J., Jun-2010, In: European Neuropsychopharmacology. 20, 6, p. 426-432 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

24 Citations (Scopus)

Processes of Change in Cognitive-Behavioural Treatment of Obsessive-Compulsive Disorder: Current Status and Some Future Directions

Polman, A., Bouman, T. K., van Hout, W. J. P. J., de Jong, P. J. & den Boer, J. A., 2010, In: Clinical psychology & psychotherapy. 17, 1, p. 1-12 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

18 Citations (Scopus)

Regional increase in P-glycoprotein function in the blood-brain barrier of patients with chronic schizophrenia: A PET study with [C-11]verapamil as a probe for P-glycoprotein function

de Klerk, O. L., Willemsen, A. T. M., Bosker, F. J., Bartels, A. L., Hendrikse, N. H., den Boer, J. A. & Dierckx, R. A., 30-Aug-2010, In: Psychiatry research: Neuroimaging. 183, 2, p. 151-156 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

65 Citations (Scopus)

Symptom Dimensions in OCD: Item-Level Factor Analysis and Heritability Estimates

Katerberg, H., Delucchi, K. L., Stewart, S. E., Lochner, C., Denys, D. A. J. P., Stack, D. E., Andresen, J. M., Grant, J. E., Kim, S. W., Williams, K. A., den Boer, J. A., van Balkom, A. J. L. M., Smit, J. H., van Oppen, P., Polman, A., Jenike, M. A., Stein, D. J., Mathews, C. A. & Cath, D. C., Jul-2010, In: Behavior Genetics. 40, 4, p. 505-517 13 p.

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106 Citations (Scopus)

235 Downloads (Pure)

The novel antidepressant agomelatine normalizes hippocampal neuronal activity and promotes neurogenesis in chronically stressed rats

Dagyte, G., Trentani, A., Postema, F., Luiten, P. G., den Boer, J. A., Gabriel, C., Mocaer, E., Meerlo, P. & van der Zee, E. A., 2010, In: CNS Neuroscience & Therapeutics. 16, 4, p. 195-207 13 p.

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57 Citations (Scopus)

104 Downloads (Pure)

The Role of the COMT Val(158)Met Polymorphism in the Phenotypic Expression of Obsessive-Compulsive Disorder

Katerberg, H., Cath, D. C., Denys, D. A. J. P., Heutink, P., Polman, A., van Nieuwerburgh, F. C. W., Deforce, D. L. D., Bochdanovits, Z., van Balkom, A. J. L. M. & den Boer, J. A., Jan-2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 1, p. 167-176 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Scopus)

2009

Antagonism of 5-HT1A receptors uncovers an excitatory effect of SSRIs on 5-HT neuronal activity, an action probably mediated by 5-HT7 receptors

Bosker, F. J., Folgering, J. H. A., Gladkevich, A. V., Schmidt, A., van der Hart, M. C. G., Sprouse, J., den Boer, J. A., Westerink, B. H. C. & Cremers, T. I. F. H., Mar-2009, In: Journal of Neurochemistry. 108, 5, p. 1126-1135 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

28 Citations (Scopus)

Association between lithium serum level, mood state, and patient-reported adverse drug reactions during long-term lithium treatment: a naturalistic follow-up study

Wilting, I., Heerdink, E. R., Mersch, P.-P. A., den Boer, J. A., Egberts, A. C. G. & Nolen, W. A., Jun-2009, In: Bipolar Disorders. 11, 4, p. 434-440 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

18 Citations (Scopus)

Chronic but not acute footshock stress leads to temporary suppression of cell proliferation in rat hippocampus

Dagyte, G., van der Zee, E. A., Postema, F., Luiten, P. G. M., den Boer, J. A., Trentani, A. & Meerlo, P., 15-Sept-2009, In: Neuroscience. 162, p. 904-913 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

76 Citations (Scopus)

11 Downloads (Pure)

Locally increased P-glycoprotein function in major depression: a PET study with [C-11]verapamil as a probe for P-glycoprotein function in the blood-brain barrier

de Klerk, O. L., Willemsen, A. T. M., Roosink, M., Bartels, A. L., Hendrikse, N. H., Bosker, F. J. & den Boer, J. A., Aug-2009, In: International Journal of Neuropsychopharmacology. 12, 7, p. 895-904 10 p.

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60 Citations (Scopus)

239 Downloads (Pure)

Patients with obsessive-compulsive disorder are impaired in associative learning based on external feedback

Nielen, M. M., den Boer, J. A. & Smid, H. G. O. M., Sept-2009, In: Psychological Medicine. 39, 9, p. 1519-1526 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

45 Citations (Scopus)

Hans den Boer

Research output

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