Harm Brugge, BSc

Search results

• 2020

  Deconvolution of bulk blood eQTL effects into immune cell subpopulations

  BIOS Consortium, Aguirre-Gamboa, R., de Klein, N., di Tommaso, J., Claringbould, A., van der Wijst, M. G. P., de Vries, D., Brugge, H., Oelen, R., Vosa, U., Zorro, M. M., Chu, X., Bakker, O. B., Borek, Z., Ricano-Ponce, I., Deelen, P., Xu, C-J., Swertz, M., Jonkers, I., Withoff, S. & 9 others, Joosten, I., Sanna, S., Kumar, V., Koenen, H. J. P. M., Joosten, L. A. B., Netea, M. G., Wijmenga, C., Franke, L. & Li, Y., 12-Jun-2020, In: Bmc Bioinformatics. 21, 1, 23 p., 243.

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  4 Citations (Scopus)

  52 Downloads (Pure)

• Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response

  de Vries, D. H., Matzaraki, V., Bakker, O. B., Brugge, H., Westra, H-J., Netea, M. G., Franke, L., Kumar, V. & van der Wijst, M. G. P., 6-Apr-2020, In: PLoS Pathogens. 16, 4, 17 p., 1008408.

  Research output: Contribution to journal › Article › Academic › peer-review

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  1 Citation (Scopus)

  84 Downloads (Pure)

• Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease

  Bangma, A., Voskuil, M. D., Uniken Venema, W. T. C., Brugge, H., Hu, S., Lanting, P., Franke, L., Dijkstra, G., Festen, E. A. M. & Weersma, R. K., Jun-2020, In: Alimentary Pharmacology & Therapeutics. 51, 11, p. 1105-1115 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  5 Citations (Scopus)

  38 Downloads (Pure)
• 2019

  Improving the diagnostic yield of exome-sequencing by predicting gene-phenotype associations using large-scale gene expression analysis

  Deelen, P., van Dam, S., Herkert, J. C., Karjalainen, J. M., Brugge, H., Abbott, K. M., van Diemen, C. C., van der Zwaag, P. A., Gerkes, E. H., Zonneveld-Huijssoon, E., Boer-Bergsma, J. J., Folkertsma, P., Gillett, T., van der Velde, K. J., Kanninga, R., van den Akker, P. C., Jan, S. Z., Hoorntje, E. T., Te Rijdt, W. P., Vos, Y. J. & 7 others, Jongbloed, J. D. H., van Ravenswaaij-Arts, C. M. A., Sinke, R., Sikkema-Raddatz, B., Kerstjens-Frederikse, W. S., Swertz, M. A. & Franke, L., 28-Jun-2019, In: Nature Communications. 10, 1, 13 p., 2837.

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  19 Citations (Scopus)

  191 Downloads (Pure)
• 2018

  An integrative approach for building personalized gene regulatory networks for precision medicine

  van der Wijst, M. G. P., de Vries, D. H., Brugge, H., Westra, H-J. & Franke, L., 19-Dec-2018, In: Genome medicine. 10, 15 p., 96.

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  14 Citations (Scopus)

  322 Downloads (Pure)

• Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs

  Lifelines Cohort Study & BIOS Consortium, 2-Apr-2018, In: Nature Genetics. 50, 4, p. 493-497 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  78 Citations (Scopus)