Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Opt1 imports CoA precursors as glutathione mixed disulphides
Wedman, J. J., de Vries, L., van Lingen, B., van der Zwaag, M., Gómez-Sánchez, R., Hardenberg, R., Huibers, W., Permentier, H., Strauss, E., Chang, M., Reggiori, F., de Kroon, A. I., Sibon, O. C. M. & Schepers, H., Sept-2025, In: The Journal of Biological Chemistry. 301, 9, 16 p., 110503.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile14 Downloads (Pure) -
Coenzyme A precursors flow from mother to zygote and from microbiome to host
Yu, Y., van der Zwaag, M., Wedman, J. J., Permentier, H., Plomp, N., Jia, X., Kanon, B., Eggens-Meijer, E., Buist, G., Harmsen, H., Kok, J., Salles, J. F., Wertheim, B., Hayflick, S. J., Strauss, E., Grzeschik, N. A., Schepers, H. & Sibon, O. C. M., 21-Jul-2022, In: Molecular Cell. 82, 14, p. 2650-2665.e12 29 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile18 Citations (Scopus)273 Downloads (Pure) -
Targeting DNA topoisomerases or checkpoint kinases results in an overload of chaperone systems, triggering aggregation of a metastable subproteome
Huiting, W., Dekker, S. L., van der Lienden, J. C. J., Mergener, R., Musskopf, M. K., Furtado, G. V., Gerrits, E., Coit, D., Oghbaie, M., Di Stefano, L. H., Schepers, H., van Waarde-Verhagen, M. A. W. H., Couzijn, S., Barazzuol, L., LaCava, J., Kampinga, H. H. & Bergink, S., 24-Feb-2022, In: eLife. 11, 29 p., e70726.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile14 Citations (Scopus)236 Downloads (Pure) -
Coenzyme A levels influence protein acetylation, CoAlation and 4'-phosphopantetheinylation: Expanding the impact of a metabolic nexus molecule
Yu, Y., Moretti, I. F., Grzeschik, N. A., Sibon, O. C. M. & Schepers, H., Apr-2021, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1868, 4, 6 p., 118965.Research output: Contribution to journal › Review article › peer-review
Open AccessFile18 Citations (Scopus)156 Downloads (Pure) -
The Hippo signaling pathway effector YAP promotes salivary gland regeneration after injury
Rocchi, C., Cinat, D., Serrano Martinez, P., Jellema-de Bruin, A. L., Baanstra, M., Brouwer, U., Del Angel Zuivre, C., Schepers, H., van Os, R., Barazzuol, L. & Coppes, R. P., 7-Dec-2021, In: Science signaling. 14, 712, 11 p., 0599.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile13 Citations (Scopus)446 Downloads (Pure)
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CITED2 cooperates with low PU.1 and DNMT3A to maintain selfrenewal in hematopoietic stem cells
Schepers, H. (Speaker)
7-Jun-2016Activity: Talk and presentation › Academic presentation › Academic
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Decreased PU.1 and enhanced CITED2 cooperate to maintain self-renewal.
Schepers, H. (Speaker), Korthuis, P. M. (Speaker), Schuringa, J. J. (Speaker), Haan, de, G. (Speaker) & Vellenga, E. (Speaker)
2013Activity: Talk and presentation › Academic presentation › Academic
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Master regulators in leukemic stem cell biology: Ex Cited(2) by PU.1.
Schepers, H. (Invited speaker)
2012Activity: Talk and presentation › Academic presentation › Academic
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Master regulators in leukemic stem cell biology: Ex Cited(2) by PU.1.
Schepers, H. (Speaker)
2012Activity: Talk and presentation › Professional or public presentation › Professional
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CITED2 modulates differentiation and proliferation of normal and leukemic hematopoietic stem and progenitor cells downstream of PU.1.
Schepers, H. (Speaker), Korthuis, P. M. (Speaker), Schuringa, J. J. (Speaker), Haan, de, G. (Speaker) & Vellenga, E. (Speaker)
10-Dec-2011Activity: Talk and presentation › Academic presentation › Academic