Research output per year
Research output per year
Personal profile
Research interests
PhD project: RNA secondary structures in the evolution of Flaviviruses
Thanks to their error-prone RNA polymerases, Flaviviruses exist in their hosts as genetically diversified populations of related genomes. In arthropod-borne flaviviruses (ssRNA+ viruses) which normally switch between arthropod and human hosts, the viral population is cyclically exposed to different and strong evolutionary forces. Among all the factors contributing to viral evolution, I’m interested in RNA secondary structures.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Genome-scale deconvolution of RNA structure ensembles
Morandi, E., Manfredonia, I., Simon, L. M., Anselmi, F., van Hemert, M. J., Oliviero, S. & Incarnato, D., Feb-2021, In: Nature Methods. 18, p. 249-252 4 p., s41592-021-01075-w.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile84 Citations (Scopus)98 Downloads (Pure) -
RNA Post-Transcriptional Modification Mapping Data Analysis Using RNA Framework
Manfredonia, I. & Incarnato, D., 4-Jun-2021, RNA Modifications. Methods in Molecular Biology. McMahon, M. (ed.). Springer, p. 3-13 11 p. (Methods in Molecular Biology; vol. 2298).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
5 Citations (Scopus) -
Structure and regulation of coronavirus genomes: State-of-the-art and novel insights from SARS-CoV-2 studies
Manfredonia, I. & Incarnato, D., Mar-2021, In: Biochemical Society Transactions. 49, 1, p. 341-352 12 p., BST20200670.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile36 Citations (Scopus)147 Downloads (Pure) -
Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements
Manfredonia, I., Nithin, C., Ponce-Salvatierra, A., Ghosh, P., Wirecki, T. K., Marinus, T., Ogando, N. S., Snijder, E. J., van Hemert, M. J., Bujnicki, J. M. & Incarnato, D., 16-Dec-2020, In: Nucleic Acids Research. 48, 22, p. 12436-12452 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile181 Citations (Scopus)450 Downloads (Pure)