Jakob Viel

View Scopus Profile

Phone+31 50 363 2088
EmailJ.H.Vielrugnl

Nijenborgh7, Gebouw 5172, ruimte 0868
9747 AG Groningen
Netherlands

11 Article
3 Review article
1 Thesis fully internal (DIV)

15 results

2025
Toward single-molecule protein sequencing using nanopores
Lu, C., Bonini, A., Viel, J. H. & Maglia, G., 17-Mar-2025, In: Nature Biotechnology. 43, 3, p. 312-322 11 p.
Research output: Contribution to journal › Review article › peer-review
2 Citations (Scopus)
2024
Guiding antibiotics towards their target using bacteriophage proteins
Zhao, X., Zhong, X., Yang, S., Deng, J., Deng, K., Huang, Z., Li, Y., Yin, Z., Liu, Y., Viel, J. H. & Wan, H., 20-Jun-2024, In: Nature Communications. 15, 1, 17 p., 5287.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
13 Citations (Scopus)

149 Downloads (Pure)
2022
Heterologous expression of the lanthipeptide mersacidin in Escherichia coli: biosynthesis, processing and engineering
Viel, J., 2022, [Groningen]: University of Groningen. 223 p.
Research output: Thesis › Thesis fully internal (DIV)

Open Access
File
757 Downloads (Pure)
Modular Use of the Uniquely Small Ring A of Mersacidin Generates the Smallest Ribosomally Produced Lanthipeptide
Viel, J. H. & Kuipers, O. P., 16-Sept-2022, In: ACS Synthetic Biology. 11, 9, p. 3078-3087 10 p., 2c00343.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
4 Citations (Scopus)

100 Downloads (Pure)
Mutational Studies of the Mersacidin Leader Reveal the Function of Its Unique Two-Step Leader Processing Mechanism
Viel, J. H. & Kuipers, O. P., 20-May-2022, In: ACS Synthetic Biology. 11, 5, p. 1949–1957 9 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
10 Citations (Scopus)

124 Downloads (Pure)
2021
Characterization of Leader Processing Shows That Partially Processed Mersacidin Is Activated by AprE After Export
Viel, J. H., van Tilburg, A. Y. & Kuipers, O. P., Oct-2021, In: Frontiers in Microbiology. 12, 10 p., 765659.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
9 Citations (Scopus)

97 Downloads (Pure)
Heterologous Expression of Mersacidin in Escherichia coli Elucidates the Mode of Leader Processing
Viel, J. H., Jaarsma, A. H. & Kuipers, O. P., Apr-2021, In: ACS Synthetic Biology. 10, 3, p. 600-608 9 p., acssynbio.0c00601.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
22 Citations (Scopus)

117 Downloads (Pure)
New developments in RiPP discovery, enzymology and engineering
Montalbán-López, M., Scott, T. A., Ramesh, S., Rahman, I. R., van Heel, A. J., Viel, J. H., Bandarian, V., Dittmann, E., Genilloud, O., Goto, Y., Grande Burgos, M. J., Hill, C., Kim, S., Koehnke, J., Latham, J. A., Link, A. J., Martínez, B., Nair, S. K., Nicolet, Y. & Rebuffat, S. & 16 others, Sahl, H.-G., Sareen, D., Schmidt, E. W., Schmitt, L., Severinov, K., Süssmuth, R. D., Truman, A. W., Wang, H., Weng, J.-K., van Wezel, G. P., Zhang, Q., Zhong, J., Piel, J., Mitchell, D. A., Kuipers, O. P. & van der Donk, W. A., 2021, In: Natural product reports. 38, 1, p. 130-239 110 p., D0NP00027B.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
500 Citations (Scopus)

1739 Downloads (Pure)
Rapid and selective chemical editing of Ribosomally synthesized and Post-translationally modified Peptides (RiPPs) via Cu(II)-catalyzed β-borylation of dehydroamino acids
de Vries, R. H., Viel, J. H., Kuipers, O. P. & Roelfes, G., 19-Feb-2021, In: Angewandte Chemie (International ed. in English). 60, 8, p. 3946-3950 5 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
29 Citations (Scopus)

164 Downloads (Pure)
Semisynthetic Macrocyclic Lipo-lanthipeptides Display Antimicrobial Activity Against Bacterial Pathogens
Zhao, X., Xu, Y., Viel, J. H. & Kuipers, O. P., 20-Aug-2021, In: ACS Synthetic Biology. 10, 8, p. 1980-1991 12 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
17 Citations (Scopus)

177 Downloads (Pure)
2020
Conjugation of Synthetic Polyproline Moietes to Lipid II Binding Fragments of Nisin Yields Active and Stable Antimicrobials
Deng, J., Viel, J. H., Kubyshkin, V., Budisa, N. & Kuipers, O. P., 20-Nov-2020, In: Frontiers in Microbiology. 11, 9 p., 575334.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
11 Citations (Scopus)

89 Downloads (Pure)
Synthesis and Characterization of Heterodimers and Fluorescent Nisin Species by Incorporation of Methionine Analogues and Subsequent Click Chemistry
Deng, J., Viel, J. H., Chen, J. & Kuipers, O. P., 18-Sept-2020, In: ACS Synthetic Biology. 9, 9, p. 2525-2536 12 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
18 Citations (Scopus)

196 Downloads (Pure)
2019
Selective Modification of RiPPs via Diels-Alder Cycloadditions on Dehydroalanine Residues
de Vries, R., Viel, J., Oudshoorn, R., Kuipers, O. & Roelfes, G., 1-Oct-2019, In: Chemistry. 25, 55, p. 12698–12702 5 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
27 Citations (Scopus)

162 Downloads (Pure)
2018
BAGEL4: a user-friendly web server to thoroughly mine RiPPs and bacteriocins
van Heel, A. J., de Jong, A., Song, C., Viel, J. H., Kok, J. & Kuipers, O. P., 2-Jul-2018, In: Nucleic Acids Research. 46, W1, p. W278-W281 4 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
File
738 Citations (Scopus)

426 Downloads (Pure)
2017
Major gene-regulatory mechanisms operating in ribosomally synthesized and post-translationally modified peptide (RiPP) biosynthesis
Bartholomae, M., Buivydas, A., Viel, J. H., Montalban-Lopez, M. & Kuipers, O. P., Oct-2017, In: Molecular Microbiology. 106, 2, p. 186-206 21 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
28 Citations (Scopus)

85 Downloads (Pure)

Jakob Viel, PhD

Research output

Search results