Research output per year
Research output per year
Personal profile
Research interests
For the latest information please consult the resources below.
Personal Website - http://www.macromolecule.fun
Twitter - https://twitter.com/macro_momo
ORCID - https://orcid.org/0000-0002-6307-7713
External positions
Research Associate Professor, Laboratory of Cellular and Structural Biology, The Rockefeller University
Jun-2019 → …
Founder, Managing Director, B13LOGY LLC
2016 → …
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Affinity-Based Interactome Analysis of Endogenous LINE-1 Macromolecules
Di Stefano, L. H., Saba, L. J., Oghbaie, M., Jiang, H., McKerrow, W., Benitez-Guijarro, M., Taylor, M. S. & LaCava, J., 2023, Methods in Molecular Biology. Humana Press, p. 215-256 42 p. (Methods in Molecular Biology; vol. 2607).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
-
Expression of L1 retrotransposons in granulocytes from patients with active systemic lupus erythematosus
Ukadike, K. C., Najjar, R., Ni, K., Laine, A., Wang, X., Bays, A., Taylor, M. S., LaCava, J. & Mustelin, T., 10-May-2023, In: Mobile dna. 14, 15 p., 5.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)2 Downloads (Pure) -
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker
Taylor, M. S., Wu, C., Fridy, P. C., Senussi, Y., Cheng, W-C., Heaps, J., Mori, K., Cohen, L., Molloy, K. R., Chait, B. T., Goggins, M., Bhan, I., Franses, J. W., Yang, X., Taplin, M-E., Wang, X., Christiani, D. C., Johnson, B. E., Meyerson, M., Uppaluri, R., & 28 others, 25-Jan-2023, BioRxiv, (bioRxiv).Research output: Working paper › Preprint › Academic
Open Access -
LINE-1 expression in cancer correlates with p53 mutation, copy number alteration, and S phase checkpoint
McKerrow, W., Wang, X., Mendez-Dorantes, C., Mita, P., Cao, S., Grivainis, M., Ding, L., LaCava, J., Burns, K. H., Boeke, J. D. & Fenyo, D., 15-Feb-2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 8, 11 p., e2115999119.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile16 Citations (Scopus)51 Downloads (Pure) -
Targeting DNA topoisomerases or checkpoint kinases results in an overload of chaperone systems, triggering aggregation of a metastable subproteome
Huiting, W., Dekker, S. L., van der Lienden, J. C. J., Mergener, R., Musskopf, M. K., Furtado, G. V., Gerrits, E., Coit, D., Oghbaie, M., Di Stefano, L. H., Schepers, H., van Waarde-Verhagen, M. A. W. H., Couzijn, S., Barazzuol, L., LaCava, J., Kampinga, H. H. & Bergink, S., 24-Feb-2022, In: eLife. 11, 29 p., e70726.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)37 Downloads (Pure)
Activities
-
Driving biomedical discovery through adventures in affinity proteomics
John LaCava (Invited speaker)
24-Mar-2023Activity: Talk and presentation › Academic presentation › Academic
-
Mobile dna (Journal)
John LaCava (Editorial board member)
Apr-2023 → …Activity: Peer-review and editorial work › Editorial work › Academic
-
Where the hell is ORF2p?!!
John LaCava (Invited speaker)
8-Jun-2022Activity: Talk and presentation › Academic presentation › Academic
-
Bio-protocol (External organisation)
John LaCava (Member)
May-2022 → …Activity: Membership › Professional
-
BioHack Academy: John LaCava - CRISPR research in Artistic Context
John LaCava (Speaker)
4-Apr-2022Activity: Talk and presentation › Professional or public presentation › Professional
Datasets
-
Aggregation under genotoxic conditions in HEK293T and U2OS cells
LaCava, J. (Creator) & di Stefano, L. (Creator), University of Groningen, 7-Apr-2022
https://www.ebi.ac.uk/pride/archive/projects/PXD030166
Dataset
-
Colorectal cancer anti-ORF1p LFQ IP-MS
LaCava, J. (Creator), University of Groningen, 23-Aug-2019
https://www.ebi.ac.uk/pride/archive/projects/PXD013743
Dataset
-
Multi-condition affinity capture/MS analysis of LAP-tagged human NCBP1, NCBP2, and NCBP3
LaCava, J. (Creator), University of Groningen, 2020
https://www.ebi.ac.uk/pride/archive/projects/PXD016038
Dataset
-
LFQMS of RING2 (RING1B, RNF2) immunoprecipitation from MDA-MB-231 and T47D breast cancer cells
LaCava, J. (Creator), University of Groningen, 19-Oct-2018
https://www.ebi.ac.uk/pride/archive/projects/PXD009570
Dataset
-
MOESM6 of LINE-1 ORF2p expression is nearly imperceptible in human cancers
Ardeljan, D. (Contributor), Wang, X. (Contributor), Oghbaie, M. (Contributor), Taylor, M. S. (Contributor), Husband, D. (Contributor), Deshpande, V. (Contributor), Steranka, J. P. (Contributor), Gorbounov, M. (Contributor), Yang, W. R. (Contributor), Sie, B. (Contributor), Larman, H. B. (Contributor), Jiang, H. (Contributor), Molloy, K. R. (Contributor), Altukhov, I. (Contributor), Li, Z. (Contributor), McKerrow, W. (Contributor), Fenyö, D. (Contributor), Burns, K. H. (Contributor) & LaCava, J. (Contributor), University of Groningen, 1-Jan-2020
DOI: 10.6084/m9.figshare.11491050.v1, https://doi.org/10.6084%2Fm9.figshare.11491050.v1
Dataset
Press/Media
-
Iris.ai Research Spotlight: John LaCava
20/04/2018
1 Media contribution
Press/Media: Expert Comment › Professional
-
Prizes
-
NCDIR fellowship
LaCava, John (Recipient), May-2012
Prize: Fellowship awarded competitively › Academic
-
Massachusetts Bay Community College Distinguished Alumni Award
LaCava, John (Recipient), May-2008
Prize: Honorary degree › Academic
-
EMBO Long Term Fellowship
LaCava, John (Recipient), Dec-2005
Prize: Fellowship awarded competitively › Academic