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John LaCava

 https://orcid.org/0000-0002-6307-7713

Personal profile

Research interests

For the latest information please consult the resources below.
Personal Website - http://www.macromolecule.fun
Twitter - https://twitter.com/macro_momo
ORCID - https://orcid.org/0000-0002-6307-7713 

Others
http://copurification.org/
http://www.ncdir.org/

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 17 - Partnerships for the Goals

External positions

Research Associate Professor, Laboratory of Cellular and Structural Biology, The Rockefeller University

Jun-2019 → …

Founder, Managing Director, B13LOGY LLC

2016 → …

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Collaborations and top research areas from the last five years

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  • Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms

    Sun, S., You, E., Hong, J., Hoyos, D., Del Priore, I., Tsanov, K. M., Mattagajasingh, O., Di Gioacchino, A., Marhon, S. A., Chacon-Barahona, J., Li, H., Jiang, H., Hozeifi, S., Rosas-Bringas, O., Xu, K. H., Song, Y., Lang, E. R., Rojas, A. S., Nieman, L. T. & Patel, B. K. & 12 others, Murali, R., Chanda, P., Karacay, A., Vabret, N., De Carvalho, D. D., Zenklusen, D., LaCava, J., Lowe, S. W., Ting, D. T., Iacobuzio-Donahue, C. A., Solovyov, A. & Greenbaum, B. D., 10-Dec-2024, In: Immunity. 57, 12, p. 2879-2894.e11 27 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    2 Citations (Scopus)
    16 Downloads (Pure)

  • CCDC88B interacts with RASAL3 and ARHGEF2 and regulates dendritic cell function in neuroinflammation and colitis

    Olivier, J. F., Langlais, D., Jeyakumar, T., Polyak, M. J., Galarneau, L., Cayrol, R., Jiang, H., Molloy, K. R., Xu, G., Suzuki, H., LaCava, J., Gros, P. & Fodil, N., 10-Jan-2024, In: Communications biology. 7, 19 p., 77.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    2 Citations (Scopus)
    83 Downloads (Pure)

  • Multiparameter screen optimizes immunoprecipitation

    Xie, S., Saba, L., Jiang, H., Bringas, O. R., Oghbaie, M., Stefano, L. D., Sherman, V. & LaCava, J., Apr-2024, In: Biotechniques. 76, 4, p. 145-152 8 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    32 Downloads (Pure)

  • Structures, functions and adaptations of the human LINE-1 ORF2 protein

    Baldwin, E. T., van Eeuwen, T., Hoyos, D., Zalevsky, A., Tchesnokov, E. P., Sánchez, R., Miller, B. D., Di Stefano, L. H., Ruiz, F. X., Hancock, M., Işik, E., Mendez-Dorantes, C., Walpole, T., Nichols, C., Wan, P., Riento, K., Halls-Kass, R., Augustin, M., Lammens, A. & Jestel, A. & 25 others, Upla, P., Xibinaku, K., Congreve, S., Hennink, M., Rogala, K. B., Schneider, A. M., Fairman, J. E., Christensen, S. M., Desrosiers, B., Bisacchi, G. S., Saunders, O. L., Hafeez, N., Miao, W., Kapeller, R., Zaller, D. M., Sali, A., Weichenrieder, O., Burns, K. H., Götte, M., Rout, M. P., Arnold, E., Greenbaum, B. D., Romero, D. L., LaCava, J. & Taylor, M. S., 1-Feb-2024, In: Nature. 626, p. 194–206 13 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    32 Citations (Scopus)
    620 Downloads (Pure)

  • Subcellular location of L1 retrotransposon-encoded ORF1p, reverse transcription products, and DNA sensors in lupus granulocytes

    Moadab, F., Sohrabi, S., Wang, X., Najjar, R., Wolters, J. C., Jiang, H., Miao, W., Romero, D., Zaller, D. M., Tran, M., Bays, A., Taylor, M. S., Kapeller, R., LaCava, J. & Mustelin, T., 27-Jun-2024, In: Mobile dna. 15, 14 p., 14.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    File
    1 Citation (Scopus)
    49 Downloads (Pure)
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