Research output per year
Research output per year
Personal profile
Research interests
Over the last decade it has become clear that non-coding RNAs are important players in virtually all physiological processes. Deregulation of non-coding RNAs contributes to diseases including cancer.
In our studies we focus on understanding how small and long non-coding RNAs contribute to the pathogenesis of B-cell lymphoma. These include studies on MYC –regulated miRNAs and lncRNAs, miRNA-lncRNA interactions and the role of lncRNAs in epigenetics.
Keywords: B-cell lymphoma, non-coding RNAs, microRNA, lncRNAs
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Circular ZDHHC11 supports Burkitt lymphoma growth independent of its miR-150 binding capacity
Liu, Y., Zhao, X., Seitz, A., Hooijsma, A. A., Ravanbakhsh, R., Sheveleva, S., de Jong, D., Koerts, J., Dzikiewicz-Krawczyk, A., van den Berg, A., Ziel-Swier, L. J. Y. M. & Kluiver, J., 16-Apr-2024, In: Scientific Reports. 14, 9 p., 8730.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)64 Downloads (Pure) -
Core regions in immunoglobulin heavy chain enhancers essential for survival of non-Hodgkin lymphoma cells are identified by a CRISPR interference screen
Kasprzyk, M. E., Sura, W., Podralska, M., Kazimierska, M., Seitz, A., Łosiewski, W., Woźniak, T., Guikema, J. E. J., Diepstra, A., Kluiver, J., Van den Berg, A., Rozwadowska, N. & Dzikiewicz-Krawczyk, A., 27-Jun-2024, (E-pub ahead of print) In: Haematologica.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Downloads (Pure) -
Detection of circulating tumor DNA in plasma of patients with primary CNS lymphoma by digital droplet PCR
Zhong, Y., Tan, G. W., Bult, J., Veltmaat, N., Plattel, W., Kluiver, J., Enting, R., Diepstra, A., van den Berg, A. & Nijland, M., 2-Apr-2024, In: BMC Cancer. 24, 6 p., 407.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)89 Downloads (Pure) -
Inhibition of the glutamate-cysteine ligase catalytic subunit with buthionine sulfoximine enhances the cytotoxic effect of doxorubicin and cyclophosphamide in Burkitt lymphoma cells
Kazimierska, M., Leśniewska, A., Bakker, A., Diepstra, A., Kasprzyk, M. E., Podralska, M., Rassek, K., Kluiver, J., van den Berg, A., Rozwadowska, N. & Dzikiewicz-Krawczyk, A., Feb-2024, In: Journal of Applied Genetics. 65, p. 95–101 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)12 Downloads (Pure) -
Pinpointing Functionally Relevant miRNAs in Classical Hodgkin Lymphoma Pathogenesis
Pan, Y., Cengiz, R., Kluiver, J., Diepstra, A. & Van den Berg, A., 12-Mar-2024, In: Cancers. 16, 6, 17 p., 1126.Research output: Contribution to journal › Review article › peer-review
Open AccessFile44 Downloads (Pure)
Activities
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Progress report of ZDHHC11 project funded by Lymph&Co
van den Berg, A. (Contributor) & Kluiver, J. (Contributor)
14-Sept-2022Activity: Talk and presentation › Professional or public presentation › Popular
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Examination of PhD student Lucia Lorenzi
Kluiver, J. (Member of Assessment Committee)
2021Activity: Examination, teaching and supervision › Examination, teaching and supervision external institution › Academic
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The role of noncoding RNAs in the MYC oncogenic network
Kluiver, J. (Invited speaker)
21-Nov-2019 → 23-Nov-2019Activity: Talk and presentation › Academic presentation › Academic
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MicroRNAs as regulators of lung homeostasis, abnormal repair and ageing.
Kluiver, J. (Co-supervisor), Berg, van den, A. (Supervisor), Timens, W. (Supervisor) & Brandsma, C.-A. (Supervisor)
2019Activity: Examination, teaching and supervision › Supervision and examination of PhD students of the UG › Academic
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MicroRNA expression and functional analysis in Hodgkin lymphoma
Kluiver, J. (Co-supervisor) & Berg, van den, A. (Supervisor)
2019Activity: Examination, teaching and supervision › Supervision and examination of PhD students of the UG › Academic
Datasets
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Supplementary Material for: MicroRNA High Throughput Loss-of-Function Screening Reveals an Oncogenic Role for miR-21-5p in Hodgkin Lymphoma
Yuan, Y. (Creator), Niu, F. (Creator), Nolte, I. M. (Creator), Koerts, J. (Creator), Rutgers, B. (Creator), Osinga, J. (Creator), Sarkis Azkanaz, M. (Creator), Terpstra, M. (Creator), Bystrykh, L. (Creator), Diepstra, A. (Creator), Visser, L. (Creator), Dzikiewicz-Krawczyk, A. (Creator), Kok, K. (Creator), Kluiver, J. (Creator) & van den Berg, A. (Creator), figshare, 5-Sept-2018
DOI: 10.6084/m9.figshare.7047695
Dataset
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Supplementary Material for: MicroRNA High Throughput Loss-of-Function Screening Reveals an Oncogenic Role for miR-21-5p in Hodgkin Lymphoma
Niu, F. (Contributor), Yuan, Y. (Contributor), Sarkis Azkanaz, M. (Contributor), Diepstra, A. (Contributor), Bystrykh, L. (Contributor), Visser, L. (Contributor), Dzikiewicz-Krawczyk, A. (Contributor), Osinga, J. (Contributor), Rutgers, B. (Contributor), Kok, K. (Contributor), Koerts, J. (Contributor), Terpstra, M. (Contributor), Kluiver, J. (Contributor), van den Berg, A. (Contributor), Nolte, I. M. (Contributor) & de Jong, D. (Contributor), figshare Academic Research System, 5-Sept-2018
DOI: 10.6084/m9.figshare.7047695.v1
Dataset
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Inhibition of the miR-155 target NIAM phenocopies the growth promoting effect of miR-155 in B-cell lymphoma [L1236]
Kluiver, J. (Creator), Slezak, I. (Creator) & van den Berg, J. (Creator), NCBI, 16-Jul-2015
http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70937
Dataset
Press/Media
Prizes
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Funding received from Lymph&Co for lymphoma research
Kluiver, J. (Recipient), 8-Mar-2017
Prize: Fellowship awarded competitively › Academic