Research output per year
Research output per year
Search results
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2025
Sparing of the heart facilitates recovery from cardiopulmonary side effects after thoracic irradiation
Wiedemann, J., Paruchuru, S. K., den Boef, L. E., Brouwer, U., Silljé, H. H. W., Schouten, E. M., Dickinson, M. G., van Goethem, M.-J., Coppes, R. P. & van Luijk, P., Jan-2025, In: International Journal of Radiation Oncology, Biology, Physics. 121, 1, p. 191-201 11 p.Research output: Contribution to journal › Article › Academic › peer-review
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2024
Proton therapy induces a local microglial neuroimmune response
Voshart, D. C., Klaver, M., Jiang, Y., van Weering, H. R. J., van Buuren-Broek, F., van der Linden, G. P., Cinat, D., Kiewiet, H. H., Malimban, J., Vazquez-Matias, D. A., Reali Nazario, L., Scholma, A. C., Sewdihal, J., van Goethem, M.-J., van Luijk, P., Coppes, R. P. & Barazzuol, L., Apr-2024, In: Radiotherapy and Oncology. 193, 8 p., 110117.Research output: Contribution to journal › Article › Academic › peer-review
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Radiation-induced DNA double-strand breaks in cortisol exposed fibroblasts as quantified with the novel foci-integrated damage complexity score (FIDCS)
Radstake, W. E., Parisi, A., Miranda, S., Gautam, K., Vermeesen, R., Rehnberg, E., Tabury, K., Coppes, R., van Goethem, M.-J., Brandenburg, S., Weber, U., Fournier, C., Durante, M., Baselet, B. & Baatout, S., 6-May-2024, In: Scientific Reports. 14, 1, 15 p., 10400.Research output: Contribution to journal › Article › Academic › peer-review
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2023
A Monte-Carlo-based study of a single-2D-detector proton-radiography system
Olivari, F., van Goethem, M.-J., Brandenburg, S. & van der Graaf, E. R., Aug-2023, In: Physica medica-European journal of medical physics. 112, 8 p., 102636.Research output: Contribution to journal › Article › Academic › peer-review
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Impact of proton therapy on the DNA damage induction and repair in hematopoietic stem and progenitor cells
Sioen, S., Vanhove, O., Vanderstraeten, B., De Wagter, C., Engelbrecht, M., Vandevoorde, C., De Kock, E., Van Goethem, M. J., Vral, A. & Baeyens, A., 2023, In: Scientific Reports. 13, 8 p., 16995.Research output: Contribution to journal › Article › Academic › peer-review
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The Effects of Combined Exposure to Simulated Microgravity, Ionizing Radiation, and Cortisol on the In Vitro Wound Healing Process
Radstake, W. E., Gautam, K., Miranda, S., Vermeesen, R., Tabury, K., Rehnberg, E., Buset, J., Janssen, A., Leysen, L., Neefs, M., Verslegers, M., Claesen, J., van Goethem, M. J., Weber, U., Fournier, C., Parisi, A., Brandenburg, S., Durante, M., Baselet, B. & Baatout, S., Jan-2023, In: Cells. 12, 2, 32 p., 246.Research output: Contribution to journal › Article › Academic › peer-review
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2022
Investigating the lateral dose response functions of point detectors in proton beams
Kretschmer, J., Brodbek, L., Looe, H. K., van der Graaf, E. R., van Goethem, M.-J., Kiewiet, H., Olivari, F., Meyer, C., Poppe, B. & Brandenburg, S., 21-Jul-2022, In: Physics in Medicine and Biology. 67, 14, 12 p., 145003.Research output: Contribution to journal › Article › Academic › peer-review
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Spectral fiber dosimetry with beryllium oxide for quality assurance in hadron radiation therapy
Metzner, E., Baeumer, C., Behrends, C., Debbih, A. D., Doehler, D. D., van Goethem, M. J., van der Graaf, E. R., Kahle, P., Luehr, A., Teichmann, T., Timmermann, B., Weinberger, D., Werner, T., Wulff, J. & Kormoll, T., Feb-2022, In: Journal of Instrumentation. 17, 2, 19 p., 02009.Research output: Contribution to journal › Article › Academic › peer-review
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2021
A simple microscopy setup for visualizing cellular responses to DNA damage at particle accelerator facilities
Qian, H., Hoebe, R. A., Faas, M. R., van Goethem, M. J., van der Graaf, E. R., Meyer, C., Kiewiet, H., Brandenburg, S. & Krawczyk, P. M., 15-Jul-2021, In: Scientific Reports. 11, 1, 10 p., 14528.Research output: Contribution to journal › Article › Academic › peer-review
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2020
Feasibility of quasi-prompt PET-based range verification in proton therapy
Ozoemelam, I. S., van der Graaf, E. R., van Goethem, M.-J., Kapusta, M., Zhang, N., Brandenburg, S. & Dendooven, P., 21-Dec-2020, In: Physics in Medicine and Biology. 65, 24, 22 p., 245013.Research output: Contribution to journal › Article › Academic › peer-review
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Real-Time PET Imaging for Range Verification of Helium Radiotherapy
Ozoemelam, I., van der Graaf, E., van Goethem, M. J., Kapusta, M., Zhang, N., Brandenburg, S. & Dendooven, P., 6-Oct-2020, In: Frontiers in Physics. 8, 16 p., 565422.Research output: Contribution to journal › Article › Academic › peer-review
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SOI Thin Microdosimeters for High LET Single-Event Upset Studies in Fe, O, Xe, and Cocktail Ion Beam Fields
James, B., Povoli, M., Kok, A., Goethem, M.-J., Nancarrow, M., Matsufuji, N., Jackson, M., Rosenfeld, A. B., Tran, L. T., Bolst, D., Peracchi, S., Davis, J. A., Prokopovich, D. A., Guatelli, S., Petasecca, M. & Lerch, M., Jan-2020, In: IEEE Transactions on Nuclear Science. 67, 1, p. 146-153 8 p., 8823950.Research output: Contribution to journal › Article › Academic › peer-review
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Validation of linear energy transfer computed in a Monte Carlo dose engine of a commercial treatment planning system
Wagenaar, D., Tran, L. T., Meijers, A., Marmitt, G. G., Souris, K., Bolst, D., James, B., Biasi, G., Povoli, M., Kok, A., Traneus, E., van Goethem, M.-J., Langendijk, J. A., Rosenfeld, A. B. & Both, S., Jan-2020, In: Physics in Medicine and Biology. 65, 2, 10 p., 025006.Research output: Contribution to journal › Article › Academic › peer-review
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2018
Dose and dose rate measurements in proton beams using the luminescence of beryllium oxide
Teichmann, T., Torres, M. J. G., van Goethem, M. J., van der Graaf, E. R., Henniger, J., Jahn, A., Kiewiet, H. H., Sommer, M., Ullrich, W., Weinhold, C. & Kormoll, T., Oct-2018, In: Journal of Instrumentation. 13, 16 p., 10015.Research output: Contribution to journal › Article › Academic › peer-review
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High accuracy proton relative stopping power measurement
van Abbema, J. K., van Goethem, M.-J., Mulder, J., Biegun, A. K., Greuter, M. J. W., van der Schaaf, A., Brandenburg, S. & van der Graaf, E. R., 1-Dec-2018, In: Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms. 436, p. 99-106 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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Lack of DNA Damage Response at Low Radiation Doses in Adult Stem Cells Contributes to Organ Dysfunction
Nagle, P. W., Hosper, N. A., Barazzuol, L., Jellema, A. L., Baanstra, M., van Goethem, M.-J., Brandenburg, S., Giesen, U., Langendijk, J. A., van Luijk, P. & Coppes, R. P., 15-Dec-2018, In: Clinical Cancer Research. 24, 24, p. 6583-6593 11 p.Research output: Contribution to journal › Article › Academic › peer-review
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2017
Comparative study of the effects of different radiation qualities on normal human breast cells
Juerß, D., Zwar, M., Giesen, U., Nolte, R., Kriesen, S., Baiocco, G., Puchalska, M., van Goethem, M.-J., Manda, K. & Hildebrandt, G., 25-Sept-2017, In: Radiation oncology. 12, 1, 10 p., 159.Research output: Contribution to journal › Article › Academic › peer-review
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Proton Dominance of Sub-LET Threshold GCR SEE Rate
Alia, R. G., Brugger, M., Ferlet-Cavrois, V., Brandenburg, S., Calcutt, J., Cerutti, F., Daly, E., Ferrari, A., Muschitiello, M., Santin, G., Uznanski, S., Van Goethem, M.-J. & Zadeh, A., Jan-2017, In: IEEE Transactions on Nuclear Science. 64, 1, p. 388-397 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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Radiation Hardness of dSiPM Sensors in a Proton Therapy Radiation Environment
Diblen, F., Buitenhuis, T., Solf, T., Rodrigues, P., van der Graaf, E., van Goethem, M.-J., Brandenburg, S. & Dendooven, P., Jul-2017, In: IEEE Transactions on Nuclear Science. 64, 7, p. 1891-1896 6 p.Research output: Contribution to journal › Article › Academic › peer-review
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The optimal balance between quality and efficiency in proton radiography imaging technique at various proton beam energies: A Monte Carlo study
Biegun, A. K., van Goethem, M.-J., van der Graaf, E. R., van Beuzekom, M., Koffeman, E. N., Nakaji, T., Takatsu, J., Visser, J. & Brandenburg, S., Sept-2017, In: Physica medica-European journal of medical physics. 41, p. 141-146 6 p.Research output: Contribution to journal › Article › Academic › peer-review
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2016
Improving proton therapy by metal-containing nanoparticles: Nanoscale insights
Schlathölter, T., Eustache, P., Porcel, E., Salado, D., Stefancikova, L., Tillement, O., Lux, F., Mowat, P., Biegun, A., van Goethem, M.-J., Remita, H. & Lacombe, S., 15-Apr-2016, In: International Journal of Nanomedicine. 2016, 11, p. 1549-1556 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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Proton energy and scattering angle radiographs to improve proton treatment planning: a Monte Carlo study
Biegun, A. K., Takatsu, J., Nakaji, T., van Goethem, M. J., van der Graaf, E. R., Koffeman, E. N., Visser, J. & Brandenburg, S., Dec-2016, In: Journal of Instrumentation. 11, 8 p., 12015.Research output: Contribution to journal › Article › Academic › peer-review
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Proton energy and scattering angle radiographs to improve proton treatment planning: a Monte Carlo study
Biegun, A., Takatsu, J., Nakaji, T., van Goethem, M.-J., van der Graaf, E., Koffeman, E., Visser, J. & Brandenburg, S., Dec-2016, In: Journal of Instrumentation. 11, 7 p., C12015.Research output: Contribution to journal › Article › Academic › peer-review
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Proton Radiography to Improve Proton Radiotherapy: Simulation Study at Different Proton Beam Energies
Biegun, A., Takatsu, J., van Goethem, M.-J., van der Graaf, E., van Beuzekom, M., Visser, J. & Brandenburg, S., Feb-2016, In: Acta Physica Polonica B. 47, 2, p. 329-334 6 p.Research output: Contribution to journal › Article › Academic › peer-review
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Proton radiography to improve proton therapy treatment
Takatsu, J., van der Graaf, E. R., van Goethem, M.-J., van Beuzekom, M., Klaver, T., Visser, J., Brandenburg, S. & Biegun, A. K., Jan-2016, In: Journal of Instrumentation. 11, 9 p., 01004.Research output: Contribution to journal › Article › Academic › peer-review
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Proton Radiography With Timepix Based Time Projection Chambers
Biegun, A. K., Visser, J., Klaver, T., Ghazanfari, N., van Goethem, M.-J., Koffeman, E., van Beuzekom, M. & Brandenburg, S., Apr-2016, In: Ieee transactions on medical imaging. 35, 4, p. 1099-1105 7 p.Research output: Contribution to journal › Article › Academic › peer-review
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The In Vitro Response of Tissue Stem Cells to Irradiation With Different Linear Energy Transfers
Nagle, P. W., Hosper, N. A., Ploeg, E. M., van Goethem, M.-J., Brandenburg, S., Langendijk, J. A., Chiu, R. K. & Coppes, R. P., 1-May-2016, In: International Journal of Radiation Oncology Biology Physics. 95, 1, p. 103-111 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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2015
Relative electron density determination using a physics based parameterization of photon interactions in medical DECT
van Abbema, J. K., van Goethem, M.-J., Greuter, M. J. W., van der Schaaf, A., Brandenburg, S. & van der Graaf, E. R., 7-May-2015, In: Physics in Medicine and Biology. 60, 9, p. 3825-3846 22 p.Research output: Contribution to journal › Article › Academic › peer-review
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Short-lived positron emitters in beam-on PET imaging during proton therapy
Dendooven, P., Buitenhuis, H. J. T., Diblen, F., Heeres, P. N., Biegun, A. K., Fiedler, F., van Goethem, M.-J., van der Graaf, E. R. & Brandenburg, S., 7-Dec-2015, In: Physics in Medicine and Biology. 60, 23, p. 8923-8947 25 p.Research output: Contribution to journal › Article › Academic › peer-review
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Spectra of clinical CT scanners using a portable Compton spectrometer
Duisterwinkel, E., van Abbema, J. K., van Goethem, M. J., Kawachimaru, R., Paganini, L., van der Graaf, E. R. & Brandenburg, S., Apr-2015, In: Medical Physics. 42, 4, p. 1884-1894 11 p.Research output: Contribution to journal › Article › Academic › peer-review
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2013
Fixed fluorescent images of an 80 MeV proton pencil beam
Warman, J. M., de Haas, M. P., Luthjens, L. H., Denkova, A. G., Kavatsyuk, O., van Goethem, M.-J., Kiewiet, H. H. & Brandenburg, S., Apr-2013, In: RADIATION PHYSICS AND CHEMISTRY. 85, p. 179-181 3 p.Research output: Contribution to journal › Article › Academic › peer-review
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SU‐E‐T‐60: Evaluation of a Two‐Dimensional Ionization Chamber Array for Proton Beam Dosimetry
Stelljes, T. S., Van Goethem, M., Brandenburg, S., Willborn, K. & Poppe, B., 2013, In: Medical Physics.Research output: Contribution to journal › Article › Academic › peer-review
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2012
Double isobaric analog of Li-11 in B-11
Charity, R. J., Sobotka, L. G., Hagino, K., Bazin, D., Famiano, M. A., Gade, A., Hudan, S., Komarov, S. A., Lee, J., Lobastov, S. P., Lukyanov, S. M., Lynch, W. G., Metelko, C., Mocko, M., Rogers, A. M., Sagawa, H., Sanetullaev, A., Tsang, M. B., Wallace, M. S. & van Goethem, M. J. & 1 others, , 31-Oct-2012, In: Physical Review C. 86, 4, 5 p., 041307.Research output: Contribution to journal › Article › Academic › peer-review
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High and Low LET Radiation Differentially Induce Normal Tissue Damage Signals
Niemantsverdriet, M., van Goethem, M.-J., Bron, R., Hogewerf, W., Brandenburg, S., Langendijk, J. A., van Luijk, P. & Coppes, R. P., 15-Jul-2012, In: International Journal of Radiation Oncology Biology Physics. 83, 4, p. 1291-1297 7 p.Research output: Contribution to journal › Article › Academic › peer-review
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2011
Development of a facility for high-precision irradiation of cells with carbon ions
van Goethem, M.-J., Niemantsverdriet, M., Brandenburg, S., Langendijk, J. A., Coppes, R. P. & van Luijk, P., Jan-2011, In: Medical Physics. 38, 1, p. 256-263 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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Ground-State Proton Decay of Br-69 and Implications for the Se-68 Astrophysical Rapid Proton-Capture Process Waiting Point
Rogers, A. M., Famiano, M. A., Lynch, W. G., Wallace, M. S., Amorini, F., Bazin, D., Charity, R. J., Delaunay, F., de Souza, R. T., Elson, J., Gade, A., Galaviz, D., van Goethem, M.-J., Hudan, S., Lee, J., Lobastov, S., Lukyanov, S., Matos, M., Mocko, M. & Schatz, H. & 4 others, , 24-Jun-2011, In: Physical Review Letters. 106, 25, 4 p., 252503.Research output: Contribution to journal › Article › Academic › peer-review
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Heavy ion induced damage to plasmid DNA: plateau region vs. spread out Bragg-peak
Dang, H. M., van Goethem, M. J., van der Graaf, E. R., Brandenburg, S., Hoekstra, R. A. & Schlathölter, T. A., Aug-2011, In: The European Physical Journal D. 63, 3, p. 359-367 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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2010
Plasmid DNA damage by heavy ions at spread-out Bragg peak energies
Dang, H. M., van Goethem, M. J., van der Graaf, E. R., Brandenburg, S., Hoekstra, R. & Schlatholter, T., Oct-2010, In: The European Physical Journal D. 60, 1, p. 51-58 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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2009
Geant4 simulations of proton beam transport through a carbon or beryllium degrader and following a beam line
van Goethem, M. J., van der Meer, R., Reist, H. W. & Schippers, J. M., 7-Oct-2009, In: Physics in Medicine and Biology. 54, 19, p. 5831-5846 16 p.Research output: Contribution to journal › Article › Academic › peer-review
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2008
Investigation of particle-unbound excited states in light nuclei with resonance-decay spectroscopy using a Be-12 beam
Charity, R. J., Komarov, S. A., Sobotka, L. G., Clifford, J., Bazin, D., Gade, A., Lee, J., Lukyanov, S. M., Lynch, W. G., Mocko, M., Lobastov, S. P., Rogers, A. M., Sanetullaev, A., Tsang, M. B., Wallace, M. S., Zegers, R. G. T., Hudan, S., Metelko, C., Famiano, M. A. & Wuosmaa, A. H. & 1 others, , Nov-2008, In: Physical Review C. 78, 5, 10 p., 054307.Research output: Contribution to journal › Article › Academic › peer-review
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2007
Particle decay of (12)Be excited states
Charity, R. J., Komarov, S. A., Sobotka, L. G., Clifford, J., Bazin, D., Gade, A., Lee, J., Lukyanov, S. M., Lynch, W. G., Mocko, M., Lobastov, S. P., Rogers, A. M., Sanetullaev, A., Tsang, M. B., Wallace, M. S., Hudan, S., Metelko, C., Famiano, M. A., Wuosmaa, A. H. & van Goethem, M. J., Dec-2007, In: Physical Review C. 76, 6, 10 p., 064313.Research output: Contribution to journal › Article › Academic › peer-review
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2005
Deep subthreshold pi(0) production in Ar-36+Au-197 collisions
Yahlali, N., Diaz, J., Aphecetche, L., d'Enterria, D., van Goethem, M., Hoefman, M., Kugler, A., Loehner, H., Martinez, G., Ostendorf, R., Schadmand, S., Schutz, Y., Turrisi, R., Wagner, W., Wilschut, H. & d' Enterria, D., 7-Mar-2005, In: Nuclear Physics A. 749, p. 190c-193c 4 p.Research output: Contribution to journal › Article › Academic › peer-review
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Transverse momentum distributions of neutral pions produced at deep subthreshold energies
Yahlali, N., Diaz, J., Aphecetche, L., D'Enterria, D., Martinez, G., Schutz, Y., Turrisi, R., Van Goethem, M., Hoefman, M., Loehner, H., Ostendorf, R., Schadmand, S., Wilschut, H., Kugler, A. & Wagner, W., 30-Jan-2005, In: International Journal of Modern Physics A. 20, 2-3, p. 609-611 3 p.Research output: Contribution to journal › Article › Academic › peer-review
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2004
Exclusive measurement of quasifree proton-neutron bremsstrahlung
Volkerts, M., Bacelar, J. C. S., van Goethem, M. J., Harakeh, M. N., Hoefman, M., Kalantar-Nayestanaki, N., Kopecky, S. F. A., Löhner, H., Messchendorp, J. G., Ostendorf, R. W. & Wilschut, H. W. E. M., 21-May-2004, In: Physical Review Letters. 92, 20, 4 p., 202301.Research output: Contribution to journal › Article › Academic › peer-review
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High-precision proton-proton bremsstrahlung measurements at 190 MeV
Mahjour Shafiei, M., Bacelar, J. C. S., van Goethem, M. J., Harakeh, M. N., Hoefman, M., Kalantar-Nayestanaki, N., Löhner, H., Messchendorp, J. G., Ostendorf, R. W., Volkerts, M. & Wilschut, H. W. E. M., Aug-2004, In: Physical Review C. 70, 2, 22 p., 024004.Research output: Contribution to journal › Article › Academic › peer-review
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2003
Exclusive measurement of coherent proton-deuteron bremsstrahlung
Volkerts, M., Bacelar, J., van Goethem, M., Harakeh, M., Hoefman, M., Huisman, H., Kalantar-Nayestanaki, N., Lohner, H., Messchendorp, J., Ostendorf, R., Schadmand, S., Scholten, O., Wilschut, H., Simon, R. & Wagner, V., 14-Feb-2003, In: Physical Review Letters. 90, 6, 4 p., 062301.Research output: Contribution to journal › Article › Academic › peer-review
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2002
Photon angular distribution of proton-proton bremsstrahlung at 190 MeV
Huisman, H., Bacelar, J., van Goethem, M., Harakeh, M., Hoefman, M., Kalantar-Nayestanaki, N., Löhner, H., Mahjour-Shafiei, M., Messchendorp, J., Ostendorf, R., Schadmand, S., Volkerts, M., Wilschut, H., Simon, R. & Löhner, H., Mar-2002, In: Physical Review C. 65, 3, 4 p., 031001.Research output: Contribution to journal › Article › Academic › peer-review
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Suppression of soft nuclear bremsstrahlung in proton-nucleus collisions
van Goethem, M., Aphecetche, L., Bacelar, J., Delagrange, H., Diaz, J., d'Enterria, D., Hoefman, M., Holzmann, R., Huisman, H., Kalantar-Nayestanaki, N., Kugler, A., Löhner, H., Martinez, G., Messchendorp, J., Ostendorf, R., Schadmand, S., Siemssen, R., Simon, R., Schutz, Y. & Turrisi, R. & 5 others, , 25-Mar-2002, In: Physical Review Letters. 88, 12, 4 p., 122302.Research output: Contribution to journal › Article › Academic › peer-review
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Systematics of proton-induced pion production at subthreshold energies
Wilschut, H., van Goethem, M., Löhner, H. & Ostendorf, R., Jan-2002, In: Physical Review C. 65, 1, 5 p., 014610.Research output: Contribution to journal › Article › Academic › peer-review
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2001
Coherence effects on bremsstrahlung in the nuclear medium
Löhner, H., van Goethem, M., Wilschut, H. & TAPS Collaboration, Mar-2001, In: Acta Physica Polonica B. 32, 3, p. 815-824 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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