Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 7 Affordable and Clean Energy -
SDG 8 Decent Work and Economic Growth
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Collaborations and top research areas from the last five years
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Epigenetic editing: from concept to clinic
Heller, E. A., Bintu, L. & Rots, M. G., Mar-2026, In: Nature Reviews Drug Discovery. 25, p. 227-248 22 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile13 Citations (Scopus)8 Downloads (Pure) -
Epigenetic editing to advance CAR T cell therapy
Horvathova, L., Rots, M. G. & Wiersma, V. R., 30-Mar-2026, In: Clinical Epigenetics. 18, 11 p., 50.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Downloads (Pure) -
Effective Reduction in Nuclear DNA Contamination Allows Sensitive Mitochondrial DNA Methylation Determination by LC-MS/MS
Liang, L., González Molina, L. A., Jellema, P. G., van Faassen, M., Otten, L. T. A., Mennega, K. P., Hof, I. H., Dijck-Brouwer, D. A. J., Dolga, A. M., Rots, M. G. & Niezen-Koning, K. E., 11-Sept-2025, In: International Journal of Molecular Sciences. 26, 18, 18 p., 8864.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)28 Downloads (Pure) -
Epigenetic editing and epi-drugs: a combination strategy to simultaneously target KDM4 as a novel anticancer approach
Sarno, F., Jacob, J. J., Eilers, R. E., Nebbioso, A., Altucci, L. & Rots, M. G., 19-Jun-2025, In: Clinical Epigenetics. 17, 1, 16 p., 105.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Citations (Scopus)32 Downloads (Pure) -
The Promise of Epigenetic Editing for Treating Brain Disorders
González Molina, L. A., Dolga, A. M., Rots, M. G. & Sarno, F., 17-Jan-2025, Neuroepigenetics Mechanisms in Health and Disease. van Zundert, B. & Montecino, M. (eds.). Springer, p. 111-190 80 p. (Subcellular Biochemistry; vol. 108).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
Open AccessFile3 Citations (Scopus)58 Downloads (Pure)
Activities
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Spiez Convergence
Rots, M. (Speaker)
8-Sept-2024 → 11-Sept-2024Activity: Talk and presentation › Professional or public presentation › Professional
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3rd Clinical Epigenetics International Conference
Rots, M. (Organiser)
5-Jun-2024 → 7-Jun-2024Activity: Organising and attending an event › Organising and contributing to an event › Professional
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Epigenetic editing: from criticized research tool to realistic clinical translation in only a decade.
Rots, M. (Speaker)
30-Sept-2024 → 4-Oct-2024Activity: Talk and presentation › Professional or public presentation › Professional
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7th International Conference on Epigenetics and Bioengineering
Rots, M. (Organiser)
3-Oct-2024 → 5-Oct-2024Activity: Organising and attending an event › Organising and contributing to an event › Professional
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5th annual Dutch Mitochondria Meeting
Rots, M. (Invited speaker)
11-May-2023Activity: Talk and presentation › Academic presentation › Academic
Datasets
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CCDC 1820683: Experimental Crystal Structure Determination
Geersing, A. (Contributor), Ségaud, N. (Contributor), van der Wijst, M. (Contributor), Rots, M. (Contributor) & Roelfes, G. (Contributor), University of Groningen, 30-Jan-2018
DOI: 10.5517/ccdc.csd.cc1z3kqc
Dataset
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ElectronicSupplementaryMaterial.zip from Liver transcriptomic and methylomic analyses identify transcriptional mitogen-activated protein kinase regulation in facultative hibernation of Syrian hamster
Coussement, L. (Creator), Oosterhof, M. (Creator), Guryev, V. (Creator), Reitsema, V. (Creator), Bruintjes, J. (Creator), Goris, M. (Creator), Bouma, H. R. (Creator), De Meyer, T. (Contributor), Rots, M. (Creator) & Henning, R. H. (Creator), The Royal Society, 12-May-2023
DOI: 10.6084/m9.figshare.22810598, https://rs.figshare.com/articles/dataset/ElectronicSupplementaryMaterial_zip_from_Liver_transcriptomic_and_methylomic_analyses_identify_transcriptional_mitogen-activated_protein_kinase_regulation_in_facultative_hibernation_of_Syrian_hamster/22810598
Dataset
Press/Media
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‘Epigenetic’ editing cuts cholesterol in mice
28/02/2024
1 Media contribution
Press/Media: Expert Comment › Popular
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Mitochondrial GpC and CpG DNA Hypermethylation Cause Metabolic Stress-Induced Mitophagy and Cholestophagy
16/11/2023
1 Media contribution
Press/Media: Research › Popular
Prizes
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Chair of the Royal Society for Physical and Life Sciences
Rots, M. (Recipient), 2024
Prize: Appointment › Professional
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Chair of the Scientific Advisory Board of the international society of Molecular and Clinical Epigenetics
Rots, M. (Recipient), 2024
Prize: Appointment › Professional
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Scientific Advisory Board member to IBISS
Rots, M. (Recipient), 2024
Prize: Appointment › Professional
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Founding member of the international society for Molecular and Clinical Epigenetics
Rots, M. (Recipient), 2023
Prize: National/international honour › Academic
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Chair of the "Koninklijk Natuurkundig Genootschap"
Rots, M. (Recipient), 2022
Prize: Appointment › Popular