Research output per year
Research output per year
- 30 results
Search results
-
2024
A 3D Epithelial-Mesenchymal Co-Culture Model of the Airway Wall Using Native Lung Extracellular Matrix
de Hilster, R. H. J., Reinders-Luinge, M. A., Schuil, A., Borghuis, T., Harmsen, M. C., Burgess, J. K. & Hylkema, M. N., 21-Sept-2024, In: AIMS Bioengineering. 11, 9, 28 p., 946.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile25 Downloads (Pure) -
Systemic oxidative stress may be associated with reduced IgG antibody titers against SARS-CoV-2 in vaccinated kidney transplant recipients: A post-hoc analysis of the RECOVAC-IR observational study
van Eijk, L. E., Bourgonje, A. R., Messchendorp, A. L., Bulthuis, M. L. C., Reinders-Luinge, M., Doornbos-van der Meer, B., Westra, J., den Dunnen, W. F. A., Hillebrands, J.-L., Sanders, J.-S. F., van Goor, H. & RECOVAC Collaborators , Mar-2024, In: Free Radical Biology and Medicine. 215, p. 14-24 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile40 Downloads (Pure) -
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease
Joglekar, M. M., Bekker, N. J., Koloko Ngassie, M. L., Vonk, J. M., Borghuis, T., Reinders-Luinge, M., Bakker, J., Woldhuis, R. R., Pouwels, S. D., Melgert, B. N., Timens, W., Brandsma, C.-A. & Burgess, J. K., Sept-2024, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 327, 3, p. L304-L318 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus) -
2023
Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells
Wu, D. D., Lau, A. T. Y., Xu, Y. M., Reinders-Luinge, M., Koncz, M., Kiss, A., Timens, W., Rots, M. G. & Hylkema, M. N., 22-Feb-2023, In: Epigenetics. 18, 1, 21 p., 2175522.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)121 Downloads (Pure) -
2022
A lung tissue gene expression profile of severe early onset COPD
Bekker, N., Van Nijnatten, J., Horvatovich, P., Wolters, J., Guryev, V., Kooistra, W., Reinders-Luinge, M., Woldhuis, R., Timens, W., Van Den berge, M. & Brandsma, C., 4-Sept-2022, In: European Respiratory Journal. 60, p. 3035Research output: Contribution to journal › Meeting Abstract › Academic
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2021
Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation
Lkhagvadorj, K., Zeng, Z., Meyer, K. F., Verweij, L. P., Kooistra, W., Reinders-Luinge, M., Dijkhuizen, H. W., de Graaf, I. A. M., Plösch, T. & Hylkema, M. N., Jan-2021, In: International Journal of Molecular Sciences. 22, 1, 14 p., 164.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)135 Downloads (Pure) -
2020
Prenatal smoke effect on mouse offspring Igf1 promoter methylation from fetal stage to adulthood is organ- and sex-specific
Zeng, Z., Meyer, K. F., Lkhagvadorj, K., Kooistra, W., Reinders-Luinge, M., Xu, X., Huo, X., Song, J., Plösch, T. & Hylkema, M. N., Mar-2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 3, p. L549-L561 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)71 Downloads (Pure) -
Prenatal smoke exposure dysregulates lung epithelial cell differentiation in mouse offspring - Role for AREG-induced EGFR signaling
Lkhagvadorj, K., Zeng, Z., Song, J., Reinders-Luinge, M., Kooistra, W., Song, S., Krauss-Etschmann, S., Melgert, B. N., Cao, J. & Hylkema, M. N., 1-Oct-2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 319, 4, p. L742-L751 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)269 Downloads (Pure) -
Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring
Lkhagvadorj, K., Meyer, K. F., Verweij, L. P., Kooistra, W., Reinders-Luinge, M., Dijkhuizen, H. W., de Graaf, I. A. M., Plösch, T. & Hylkema, M. N., 2020, In: Epigenetics. 15, 12, p. 1370-1385 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Citations (Scopus)160 Downloads (Pure) -
2019
A cellular census of healthy lung and asthmatic airway wall identifies novel cell states in health and disease
Braga, F. V., Kar, G., Berg, M., Carpaij, O., polanski, K., Simon, L., Brouwer, S., Gomes, T., Hesse, L., Jiang, J., Fasouli, E. S., Efremova, M., Vento-Tormo, R., Affleck, K., Palit, S., strzelecka, P., Firth, H. V., Mahbubani, K. T. A., Cvejic, A. & Meyer, K. & 13 others, , 23-Jan-2019, BioRxiv, (bioRxiv).Research output: Working paper › Preprint › Academic
Open AccessFile137 Downloads (Pure) -
A cellular census of human lungs identifies novel cell states in health and in asthma
Braga, F. A. V., Kar, G., Berg, M., Carpaij, O. A., Polanski, K., Simon, L. M., Brouwer, S., Gomes, T., Hesse, L., Jiang, J., Fasouli, E. S., Efremova, M., Vento-Tormo, R., Talavera-Lopez, C., Jonker, M. R., Affleck, K., Palit, S., Strzelecka, P. M., Firth, H. V. & Mahbubani, K. T. & 15 others, , Jul-2019, In: Nature Medicine. 25, 7, p. 1153-1163 24 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile561 Citations (Scopus)846 Downloads (Pure) -
Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution
Duclos, G. E., Teixeira, V. H., Autissier, P., Gesthalter, Y. B., Reinders-Luinge, M. A., Terrano, R., Dumas, Y. M., Liu, G., Mazzilli, S. A., Brandsma, C.-A., van den Berge, M., Janes, S. M., Timens, W., Lenburg, M. E., Spira, A., Campbell, J. D. & Beane, J., Dec-2019, In: Science Advances. 5, 12, 11 p., 3413.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile53 Citations (Scopus)157 Downloads (Pure) -
2017
Aberrant DNA methylation and expression of SPDEF and FOXA2 in airway epithelium of patients with COPD
Song, J., Heijink, I. H., Kistemaker, L. E. M., Reinders-Luinge, M., Kooistra, W., Noordhoek, J. A., Gosens, R., Brandsma, C. A., Timens, W., Hiemstra, P. S., Rots, M. G. & Hylkema, M. N., 24-Apr-2017, In: Clinical Epigenetics. 9, 10 p., 42.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile37 Citations (Scopus)380 Downloads (Pure) -
Prenatal exposure to tobacco smoke sex dependently influences methylation and mRNA levels of the Igf axis in lungs of mouse offspring
Meyer, K. F., Krauss-Etschmann, S., Kooistra, W., Reinders-Luinge, M., Timens, W., Kobzik, L., Plösch, T. & Hylkema, M. N., 5-Apr-2017, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 312, 4, p. L542-L555 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile28 Citations (Scopus)325 Downloads (Pure) -
2016
Atopy and Inhaled Corticosteroid Use Associate with Fewer IL-17(+) Cells in Asthmatic Airways
Fattahi, F., Brandsma, C.-A., Lodewijk, M., Reinders-Luinge, M., Postma, D. S., Timens, W., Hylkema, M. N. & Hacken, ten, N., 23-Aug-2016, In: PLoS ONE. 11, 8, 12 p., e0161433.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)282 Downloads (Pure) -
2015
Correction: Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
Dijkstra, A. E., Smolonska, J., van den Berge, M., Wijmenga, C., Zanen, P., Luinge, M. A., Platteel, M., Lammers, J.-W., Dahlback, M., Tosh, K., Hiemstra, P. S., Sterk, P. J., Spira, A., Vestbo, J., Nordestgaard, B. G., Benn, M., Nielsen, S. F., Dahl, M., Verschuren, W. M. & Picavet, H. S. J. & 31 others, , 30-May-2015, In: PLoS ONE. 10, 5, 1 p., e0129524.Research output: Contribution to journal › Erratum
Open AccessFile415 Downloads (Pure) -
Distinct macrophage phenotypes in allergic and nonallergic lung inflammation
Robbe, P., Draijer, C., Rebelo Borg, T., Luinge, M., Timens, W., Wouters, I. M., Melgert, B. N. & Hylkema, M. N., Feb-2015, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 308, 4, p. L358-L367 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile98 Citations (Scopus)36 Downloads (Pure) -
Farm dust directs phenotype-specific macrophage activation which may contribute to protection against Th2-related disorders
Gonçalves Dias Pereira, P., Draijer, C., Borg, T. R., Luinge, M., Timens, W., Wouters, I. M., Melgert, B. & Hylkema, M., 2015, Farming exposure and asthma phenotypes in mice and men. Groningen: Rijksuniversiteit Groningen, p. 139-147 9 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
Open AccessFile17 Downloads (Pure) -
Fluticasone propionate suppresses farm dust-induced airway hyperresponsiveness in mice but has no effect on lung neutrophils
Gonçalves Dias Pereira, P., Draijer, C., Brandsma, C.-A., Hesse, L., Luinge, M., Melgert, B., Timens, W., Wouters, I. M. & Hylkema, M., 2015, Farming exposure and asthma phenotypes in mice and men. Groningen: Rijksuniversiteit Groningen, p. 77-97 21 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
Open AccessFile30 Downloads (Pure) -
2014
Farm Dust Exposure Induces Corticosteroid Resistant Airway Neutrophilia In Mice
Robbe, P., Draijer, C., Spierenburg, E., Brandsma, C., Hesse, L., Luinge, M., Melgert, B. N., Timens, W., Wouters, I. M. & Hylkema, M. N., 2014, In: American Journal of Respiratory and Critical Care Medicine. 189, 1 p.Research output: Contribution to journal › Meeting Abstract › Academic
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Mouse Protocadherin-1 Gene Expression Is Regulated by Cigarette Smoke Exposure In Vivo
Koning, H., van Oosterhout, A. J. M., Brouwer, U., den Boef, L. E., Gras, R., Reinders-Luinge, M., Brandsma, C.-A., van der Toorn, M., Hylkema, M. N., Willemse, B. W. M., Sayers, I., Koppelman, G. H. & Nawijn, M. C., 3-Jul-2014, In: PLoS ONE. 9, 7, 10 p., e98197.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)313 Downloads (Pure) -
Pim1 kinase protects airway epithelial cells from cigarette smoke-induced damage and airway inflammation
de Vries, M., Heijink, H., Gras, R., den Boef, L. E., Reinders-Luinge, M., Pouwels, S. D., Hylkema, M., van der Toorn, M., Brouwer, U., van Oosterhout, A. J. M. & Nawijn, M. C., 1-Aug-2014, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 307, 3, p. L240-L251 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile24 Citations (Scopus)1 Downloads (Pure) -
Susceptibility to chronic mucus hypersecretion, a genome wide association study
Dijkstra, A. E., Smolonska, J., van den Berge, M., Wijmenga, C., Zanen, P., Luinge, M. A., Platteel, M., Lammers, J.-W., Dahlback, M., Tosh, K., Hiemstra, P. S., Sterk, P. J., Spira, A., Vestbo, J., Nordestgaard, B. G., Benn, M., Nielsen, S. F., Dahl, M., Verschuren, W. M. & Picavet, H. S. J. & 31 others, , 8-Apr-2014, In: PLoS ONE. 9, 4, 13 p., e91621.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile22 Citations (Scopus)254 Downloads (Pure) -
2013
Skewed Th17/th1 Immune Balance In Peripheral Blood Of Occupationally Exposed Agricultural Workers
Robbe, P., Spierenburg, E., Draijer, C., Brandsma, C., Telenga, E. D., Oosterhout, A., Van den Berge, M., Luinge, M., Melgert, B. N., Heederik, D., Timens, W., Wouters, I. M. & Hylkema, M. N., 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 1 p.Research output: Contribution to journal › Meeting Abstract › Academic
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2008
Association of mast cells with lung function in chronic obstructive pulmonary disease
Gosman, M. M., Postma, D. S., Vonk, J. M., Rutgers, B., Lodewijk, M., Smith, M., Luinge, M. A., ten Hacken, N. H. T. & Timens, W., 10-Sept-2008, In: Respiratory Research. 9, 9 p., 64.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile36 Citations (Scopus)284 Downloads (Pure) -
Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells?
Brandsma, C.-A., Hylkema, M. N., van der Strate, B. W. A., Slebos, D.-J., Luinge, M. A., Geerlings, M., Timens, W., Postma, D. S. & Kerstjens, H. A. M., 6-Feb-2008, In: Respiratory Research. 9, 12 p., 17.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile27 Citations (Scopus)241 Downloads (Pure) -
Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes
Ma, Y., Visser, L., Roelofsen, J., de Vries, M., Diepstra, A., van Imhoff, G., van der Wal, T., Luinge, M., Alvarez Llamas, G., Vos, H., Poppema, S., Vonk, R. & van den Berg, A., 15-Feb-2008, In: Blood. 111, 4, p. 2339-2346 8 p.Research output: Contribution to journal › Article › Academic › peer-review
109 Citations (Scopus) -
2007
Het identificeren van mijlpalen in de taalontwikkeling van kinderen van 1 tot 6 jaar
Luinge, M. R., Post, W. J. & Goorhuis-Brouwer, S. M., 2007, In: Stem-, spraak- en taalpathologie. 15, 1, p. 33-52 20 p.Research output: Contribution to journal › Article › Academic
Open AccessFile865 Downloads (Pure) -
Spreeknormen voor jonge kinderen: van GMS naar SNEL
Goorhuis-Brouwer, S. M., Luinge, M. R. & Post, W. J., 2007, In: Tijdschrift voor Jeugdgezondheidszorg. 39, p. 9-14 6 p.Research output: Contribution to journal › Article › Academic
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The language screening instrument SNEL
Luinge, M. R., Post, W. J. & Goorhuis-Brouwer, S. M., 2007, In: Educational & Child Psychology. 24, p. 18-28 11 p.Research output: Contribution to journal › Article › Academic
4 Citations (Scopus)