Martin Witte

Search results

• 2023

  A Predictive Model for the Pd-Catalyzed Site-Selective Oxidation of Diols

  Marinus, N., Eisink, N. N. H. M., Reintjens, N. R. M., Dijkstra, R. S., Havenith, R. W. A., Minnaard, A. J. & Witte, M. D., 4-Aug-2023, In: Chemistry – A European Journal. 29, 44, 13 p., e202300318.

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  2 Citations (Scopus)

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• PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand

  Ishizuka, S., van Dijk, J. H. M., Kawakita, T., Miyamoto, Y., Maeda, Y., Goto, M., Le Calvez, G., Groot, L. M., Witte, M. D., Minnaard, A. J., van der Marel, G. A., Ato, M., Nagae, M., Codée, J. D. C. & Yamasaki, S., 26-Jul-2023, In: ACS central science. 9, 7, p. 1388-1399 12 p.

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• Practical Site-Selective Oxidation of Glycosides with Palladium(II) Acetate/Neocuproine

  Reintjens, N. R. M., Bartels, I. M. A., Marinus, N., Massmann, S. C., Bunt, D. V., Walvoort, M. T. C., Witte, M. D. & Minnaard, A. J., 9-Nov-2023, (E-pub ahead of print) In: Synlett. 5 p.

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• Site-Selective Electrochemical Oxidation of Glycosides

  Kidonakis, M., Villotet, A., Witte, M. D., Beil, S. B. & Minnaard, A. J., 17-Feb-2023, In: ACS Catalysis. 13, 4, p. 2335-2340 6 p.

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  2 Citations (Scopus)

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• Site-selective introduction of thiols in unprotected glycosides

  Reintjens, N. R. M., Witte, M. D. & Minnaard, A. J., 2-Jun-2023, In: Organic and Biomolecular Chemistry. 21, 24, p. 5098-5103 6 p.

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  1 Citation (Scopus)

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• Synthesis of Methylene Tetrahydrofurane-Fused Carbohydrates

  Ahmadian-Moghaddam, M., Reintjens, N. R. M., Witte, M. D. & Minnaard, A. J., 22-May-2023, In: European Journal of Organic Chemistry. 26, 20, 11 p., e202300281.

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  1 Citation (Scopus)

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• The linkage-type and the exchange molecule affect the protein-labeling efficiency of iminoboronate probes

  van der Zouwen, A. J., Jeucken, A., van der Pol, E., Boerema, G., Slotboom, D. J. & Witte, M. D., 10-Nov-2023, (E-pub ahead of print) In: Organic & Biomolecular Chemistry. 9 p., d3ob01269g.

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• 2022

  Late-Stage Modification of Aminoglycoside Antibiotics Overcomes Bacterial Resistance Mediated by APH(3') Kinases

  Bastian, A. A., Bastian, M., Jäger, M., Loznik, M., Warszawik, E. M., Yang, X., Tahiri, N., Fodran, P., Witte, M. D., Thoma, A., Köhler, J., Minnaard, A. J. & Herrmann, A., 27-Jun-2022, In: Chemistry. 28, 36, 7 p., e202200883.

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  2 Citations (Scopus)

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• Palladium-Catalyzed Oxidation of Glucose in Glycopeptides

  Reintjens, N. R. M., Yakovlieva, L., Marinus, N., Hekelaar, J., Nuti, F., Papini, A. M., Witte, M. D., Minnaard, A. J. & Walvoort, M. T. C., 7-Jul-2022, In: European Journal of Organic Chemistry. 2022, 25, 7 p., e202200677.

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  3 Citations (Scopus)

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• Site-Selective Dehydroxy-Chlorination of Secondary Alcohols in Unprotected Glycosides

  Zhang, J., Reintjens, N. R. M., Dhineshkumar, J., Witte, M. D. & Minnaard, A. J., 29-Jul-2022, In: Organic letters. 24, 29, p. 5339-5344 6 p.

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  7 Citations (Scopus)

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• Site-selective Electrochemical Oxidation of Glucosides

  Kidonakis, M., Villotet, A., Witte, M., Beil, S. B. & Minnaard, A., 1-Aug-2022.

  Research output: Working paper › Academic

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• Site-Selective Modification of (Oligo)Saccharides

  Witte, M. D. & Minnaard, A. J., 7-Oct-2022, In: ACS Catalysis. 12, 19, p. 12195-12205 11 p.

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  6 Citations (Scopus)

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• α-C-H Photoalkylation of a Glucose Derivative in Continuous Flow

  Mouthaan, M. L. M. C., Pouwer, K., Borst, M. L. G., Witte, M. D. & Minnaard, A. J., 2022, In: Synthesis (Germany). 54, 21, p. 4683-4689 7 p.

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  2 Citations (Scopus)

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• 2021

  Biaryl sulfonamides as cisoid azosteres for photopharmacology

  Kobauri, P., Szymanski, W., Cao, F., Thallmair, S., Marrink, S. J., Witte, M. D., Dekker, F. J. & Feringa, B. L., 27-Apr-2021, In: Chemical Communications. 57, 34, p. 4126-4129 4 p.

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  7 Citations (Scopus)

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• Iminoboronates as Dual-Purpose Linkers in Chemical Probe Development

  van der Zouwen, A. J. N., Jeucken, A., Steneker, R., Hohmann, K. F., Lohse, J., Slotboom, D. J. & Witte, M., 15-Feb-2021, In: Chemistry. 27, 10, p. 3292-3296 5 p.

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  8 Citations (Scopus)

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• Modular Approaches to Synthesize Activity- and Affinity-Based Chemical Probes

  van der Zouwen, A. J. & Witte, M. D., 15-Apr-2021, In: Frontiers in Chemistry. 9, 17 p., 644811.

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  8 Citations (Scopus)

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• On the Origin of Regioselectivity in Palladium-Catalyzed Oxidation of Glucosides

  Wan, I. C., Hamlin, T. A., Eisink, N. N. H. M., Marinus, N., de Boer, C., Vis, C. A., Codée, J. D. C., Witte, M. D., Minnaard, A. J. & Bickelhaupt, F. M., 26-Jan-2021, In: European Journal of Organic Chemistry. 2021, 4, p. 632-636 5 p.

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  12 Citations (Scopus)

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• Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells

  Reijneveld, J. F., Marino, L., Cao, T-P., Cheng, T-Y., Dam, D., Shahine, A., Witte, M. D., Filippov, D. V., Suliman, S., van der Marel, G. A., Moody, D. B., Minnaard, A. J., Rossjohn, J., Codée, J. D. C. & Van Rhijn, I., Oct-2021, In: Journal of Biological Chemistry. 297, 4, 101197.

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  4 Citations (Scopus)

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• 2020

  Protein-Templated Hit Identification through an Ugi Four-Component Reaction**

  Mancini, F., Unver, M. Y., Elgaher, W. A. M., Jumde, V. R., Alhayek, A., Lukat, P., Herrmann, J., Witte, M. D., Köck, M., Blankenfeldt, W., Müller, R. & Hirsch, A. K. H., 17-Nov-2020, In: Chemistry - A European Journal. 26, 64, p. 14585-14593 9 p.

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  14 Citations (Scopus)

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• Selective Modification of Streptozotocin at the C3 Position to Improve Its Bioactivity as Antibiotic and Reduce Its Cytotoxicity towards Insulin-Producing β Cells

  Zhang, J., Yakovlieva, L., de Haan, B. J., de Vos, P., Minnaard, A. J., Witte, M. D. & Walvoort, M. T. C., Apr-2020, In: Antibiotics . 9, 4, 11 p., 182.

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  6 Citations (Scopus)

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• Stereoselective Protection-Free Modification of 3-Keto-saccharides

  Marinus, N., Tahiri, N., Duca, M., Mouthaan, L. M. C. M., Bianca, S., van den Noort, M., Poolman, B., Witte, M. D. & Minnaard, A. J., 17-Jul-2020, In: Organic letters. 22, 14, p. 5622-5626 5 p.

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  23 Citations (Scopus)

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• Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis

  Tahiri, N., Fodran, P., Jayaraman, D., Buter, J., Witte, M. D., Ocampo, T. A., Moody, D. B., Van Rhijn, I. & Minnaard, A. J., 4-May-2020, In: Angewandte Chemie (International ed. in English). 59, 19, p. 7555-7560 6 p.

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  11 Citations (Scopus)

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• Turnip yellow mosaic virus protease binds ubiquitin suboptimally to fine-tune its deubiquitinase activity

  Fieulaine, S., Witte, M. D., Theile, C. S., Ayach, M., Ploegh, H. L., Jupin, I. & Bressanelli, S., 2-Oct-2020, In: Journal of Biological Chemistry. 295, 40, p. 13769-13783 15 p.

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  5 Citations (Scopus)

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• 2019

  An in situ combinatorial methodology to synthesize and screen chemical probes

  van der Zouwen, A. J., Lohse, J., Wieske, L. H. E., Hohmann, K. F., van der Vlag, R. & Witte, M. D., 18-Feb-2019, In: Chemical Communications. 55, 14, p. 2050-2053 4 p.

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  10 Citations (Scopus)

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• From d- to l-Monosaccharide Derivatives via Photodecarboxylation-Alkylation

  Wan, I. C. S., Witte, M. D. & Minnaard, A. J., 20-Sept-2019, In: Organic letters. 21, 18, p. 7669-7673 5 p.

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  37 Citations (Scopus)

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• Regioselective Manipulation of GlcNAc Provides Allosamine, Lividosamine, and Related Compounds

  Zhang, J., Eisink, N. N. H. M., Witte, M. D. & Minnaard, A. J., 18-Jan-2019, In: Journal of Organic Chemistry. 84, 2, p. 516-525 10 p.

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  17 Citations (Scopus)

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• Total Synthesis of an Immunogenic Trehalose Phospholipid from Salmonella Typhi and Elucidation of Its sn-Regiochemistry by Mass Spectrometry

  Mishra, V. K., Buter, J., Blevins, M. S., Witte, M. D., Van Rhijn, I., Moody, D. B., Brodbelt, J. S. & Minnaard, A. J., 5-Jul-2019, In: Organic letters. 21, 13, p. 5126-5131 6 p.

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  4 Citations (Scopus)

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• 2018

  Activity-Based Probes for Glycosidases: Profiling and Other Applications

  Kuo, C-L., van Meel, E., Kytidou, K., Kallemeijn, W. W., Witte, M., Overkleeft, H. S., Artola, M. E. & Aerts, J. M., 2018, CHEMICAL GLYCOBIOLOGY, PT B: MONITORING GLYCANS AND THEIR INTERACTIONS. Imperiali, B. (ed.). Academic Press, Vol. 598. p. 217-235 19 p. (Methods in Enzymology; vol. 598).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
  18 Citations (Scopus)
• 2017

  A Protocol for Protein Profiling Using Chemoselective Cleavable Linker Probes in Semi-permeabilized Cells

  Claessen, J. H. L. & Witte, M. D., 2017, Activity-Based Proteomics: Methods and Protocols. Overkleeft, H. S. & Florea, B. I. (eds.). New York: Springer, Vol. 1491. p. 173-184 12 p. (Methods in Molecular Biology; vol. 1491).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

• Bicyclic enol cyclocarbamates inhibit penicillin-binding proteins

  Dockerty, P., Edens, J. G., Tol, M. B., Morales Angeles, D., Domenech Pena, A., Liu, Y., Hirsch, A. K. H., Veening, J-W., Scheffers, D-J. & Witte, M. D., 3-Jan-2017, In: Organic & Biomolecular Chemistry. 15, 4, p. 894-910 17 p.

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  6 Citations (Scopus)

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• Chemo- and Regioselective Oxidation of Secondary Alcohols in Vicinal Diols

  Eisink, N., Minnaard, A. & Witte, M., Feb-2017, In: Synthesis. 49, 4, p. 822-829 8 p.

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  11 Citations (Scopus)

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• Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes

  Kallemeijn, W. W., Scheij, S., Hoogendoorn, S., Witte, M. D., Herrera Moro Chao, D., van Roomen, C. P. A. A., Ottenhoff, R., Overkleeft, H. S., Boot, R. G. & Aerts, J. M. F. G., 16-Feb-2017, In: PLoS ONE. 12, 2, 23 p., e0170268.

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  9 Citations (Scopus)

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• Regioselective Carbohydrate Oxidations: A Nuclear Magnetic Resonance (NMR) Study on Selectivity, Rate, and Side-Product Formation

  Eisink, N. N. H. M., Witte, M. D. & Minnaard, A. J., Feb-2017, In: ACS Catalysis. 7, 2, p. 1438-1445 8 p.

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  22 Citations (Scopus)

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• Saccharide-Containing Dynamic Proteoids

  Liu, Y., Stuart, M. C. A., Witte, M. D., Buhler, E. & Hirsch, A. K. H., 16-Nov-2017, In: Chemistry. 23, 64, p. 16162-16166 5 p.

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  5 Citations (Scopus)

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• Site-selective carbon-carbon bond formation in unprotected monosaccharides using photoredox catalysis

  Wan, I. C., Witte, M. D. & Minnaard, A. J., 4-May-2017, In: Chemical Communications. 53, 36, p. 4926-4929 4 p.

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  42 Citations (Scopus)

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• Stabilization of Glucocerebrosidase by Active Site Occupancy

  Bdira, F. B., Kallemeijn, W. W., Oussoren, S. V., Scheij, S., Bleijlevens, B., Florea, B. I., van Roomen, C. P. A. A., Ottenhoff, R., van Kooten, M. J. F. M., Walvoort, M. T. C., Witte, M. D., Boot, R. G., Ubbink, M., Overkleeft, H. S. & Aerts, J. M. F. G., Jul-2017, In: ACS chemical biology. 12, 7, p. 1830-1841 12 p.

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  16 Citations (Scopus)

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• Target and identify: triazene linker helps identify azidation sites of labelled proteins via click and cleave strategy

  Lohse, J., Schindl, A., Danda, N., Williams, C. P., Kramer, K., Kuster, B., Witte, M. D. & Médard, G., 11-Nov-2017, In: Chem. Commun.. 53, 87, p. 11929-11932 4 p.

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  3 Citations (Scopus)

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• Targeted Diazotransfer Reagents Enable Selective Modification of Proteins with Azides

  Lohse, J., Swier, L. J. Y. M., Oudshoorn, R. C., Médard, G., Kuster, B., Slotboom, D. J. & Witte, M. D., Apr-2017, In: BIOCONJUGATE CHEMISTRY. 28, 4, p. 913-917 5 p.

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  22 Citations (Scopus)

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• 2016

  C3 Epimerization of Glucose, via Regioselective Oxidation and Reduction

  Jumde, V. R., Eisink, N. N. H. M., Witte, M. D. & Minnaard, A. J., 18-Nov-2016, In: Journal of Organic Chemistry. 81, 22, p. 11439-11443 5 p.

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  27 Citations (Scopus)

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• Deuteration enhances catalyst lifetime in palladium-catalysed alcohol oxidation

  Armenise, N., Tahiri, N., Eisink, N. N. H. M., Denis, M., Jäger, M., De Vries, J. G., Witte, M. D. & Minnaard, A. J., 4-Jan-2016, In: Chemical communications (Cambridge, England). 52, 10, p. 2189-2191 3 p.

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  23 Citations (Scopus)

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• Endo-β-Glucosidase Tag Allows Dual Detection of Fusion Proteins by Fluorescent Mechanism-Based Probes and Activity Measurement

  Kallemeijn, W. W., Scheij, S., Voorn-Brouwer, T. M., Witte, M. D., Verhoek, M., Overkleeft, H. S., Boot, R. G. & Aerts, J. M. F. G., 15-Sept-2016, In: ChemBioChem. 17, 18, p. 1698-1704 7 p.

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  2 Citations (Scopus)

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• Regioselective oxidation of unprotected 1,4 linked glucans

  Eisink, N. N. H. M., Lohse, J., Witte, M. D. & Minnaard, A. J., 7-Jun-2016, In: Organic & Biomolecular Chemistry. 14, 21, p. 4859-4864 6 p.

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  24 Citations (Scopus)

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• 2015

  Metabolic alkene labeling and in vitro detection of histone acylation via the aqueous oxidative Heck reaction

  Ourailidou, M. E., Dockerty, P., Witte, M., Poelarends, G. J. & Dekker, F. J., 12-Feb-2015, In: Organic & Biomolecular Chemistry. 13, 12, p. 3648-3653 6 p.

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  18 Citations (Scopus)

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• Site-specific protein modification using immobilized sortase in batch and continuous-flow systems

  Witte, M. D., Wu, T., Guimaraes, C. P., Theile, C. S., Blom, A. E. M., Ingram, J. R., Li, Z., Kundrat, L., Goldberg, S. D. & Ploegh, H. L., Mar-2015, In: Nature protocols. 10, 3, p. 508-516 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  45 Citations (Scopus)
• 2014

  A Sensitive Gel-based Method Combining Distinct Cyclophellitol-based Probes for the Identification of Acid/Base Residues in Human Retaining β-Glucosidases

  Kallemeijn, W. W., Witte, M. D., Voorn-Brouwer, T. M., Walvoort, M. T. C., Li, K-Y., Codee, J. D. C., van der Marel, G. A., Boot, R. G., Overkleeft, H. S. & Aerts, J. M. F. G., 19-Dec-2014, In: The Journal of Biological Chemistry. 289, 51, p. 35351-35362 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  18 Citations (Scopus)

• Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity

  Wagner, K., Kwakkenbos, M. J., Claassen, Y. B., Maijoor, K., Bohne, M., van der Sluijs, K. F., Witte, M. D., van Zoelen, D. J., Cornelissen, L. A., Beaumont, T., Bakker, A. Q., Ploegh, H. L. & Spits, H., 25-Nov-2014, In: Proceedings of the National Academy of Science of the United States of America. 111, 47, p. 16820-16825 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  61 Citations (Scopus)

• Exploring functional cyclophellitol analogues as human retaining beta-glucosidase inhibitors

  Li, K-Y., Jiang, J., Witte, M. D., Kallemeijn, W. W., Donker-Koopman, W. E., Boot, R. G., Aerts, J. M. F. G., Codee, J. D. C., van der Marel, G. A. & Overkleeft, H. S., 21-Oct-2014, In: Organic & Biomolecular Chemistry. 12, 39, p. 7786-7791 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)

• From covalent glycosidase inhibitors to activity-based glycosidase probes

  Willems, L. I., Jiang, J., Li, K-Y., Witte, M. D., Kallemeijn, W. W., Beenakker, T. J. N., Schroeder, S. P., Aerts, J. M. F. G., van der Marel, G. A., Codee, J. D. C. & Overkleeft, H. S., 25-Aug-2014, In: Chemistry. 20, 35, p. 10864-10872 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  41 Citations (Scopus)

• Mechanism-based inhibitors of glycosidases: Design and applications

  Kallemeijn, W. W., Witte, M. D., Wennekes, T. & Aerts, J. M. F. G., 2014, Advances in Carbohydrate Chemistry and Biochemistry. Horton, D. (ed.). SAN DIEGO: Academic Press, Vol. 71. p. 297-338 42 p. (Advances in Carbohydrate Chemistry and Biochemistry; vol. 71).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
  30 Citations (Scopus)

• Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

  Avalos, A. M., Bilate, A. M., Witte, M. D., Tai, A. K., He, J., Frushicheva, M. P., Thill, P. D., Meyer-Wentrup, F., Theile, C. S., Chakraborty, A. K., Zhuang, X. & Ploegh, H. L., 10-Feb-2014, In: Journal of Experimental Medicine. 211, 2, p. 365-379 15 p.

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  46 Citations (Scopus)

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