Martina Schmidt

2024

Analysis of Adverse Reactions Associated with the Use of Crataegus-Containing Herbal Products

Woerdenbag, H. J., Ursidae, M., Ekhart, C., Schmidt, M., Vitalone, A. & van Hunsel, F. P. A. M., Nov-2024, In: Pharmaceuticals. 17, 11, 27 p., 1490.

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Diesel exhaust particles alter mitochondrial bioenergetics and cAMP producing capacity in human bronchial epithelial cells

Cattani-Cavalieri, I., Trombetta-Lima, M., Yan, H., Manzano-Covarrubias, A. L., Baarsma, H. A., Oun, A., van der Veen, M. M., Oosterhout, E., Dolga, A. M., Ostrom, R. S., Valenca, S. S. & Schmidt, M., 25-Jul-2024, In: Frontiers in Toxicology. 6, 1412864.

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2 Citations (Scopus)

20 Downloads (Pure)

Dropout from exercise trials among cancer survivors: An individual patient data meta-analysis from the POLARIS study

Western, B., Ivarsson, A., Vistad, I., Demmelmaier, I., Aaronson, N. K., Radcliffe, G., van Beurden, M., Bohus, M., Courneya, K. S., Daley, A. J., Galvão, D. A., Garrod, R., Goedendorp, M. M., Griffith, K. A., van Harten, W. H., Hayes, S. C., Herrero-Roman, F., Hiensch, A. E., Irwin, M. L. & James, E. & 27 others, Kenkhuis, M.-F., Kersten, M. J., Knoop, H., Lucia, A., May, A. M., McConnachie, A., van Mechelen, W., Mutrie, N., Newton, R. U., Nollet, F., Oldenburg, H. S., Plotnikoff, R., Schmidt, M. E., Schmitz, K. H., Schulz, K.-H., Short, C. E., Sonke, G. S., Steindorf, K., Stuiver, M. M., Taaffe, D. R., Thorsen, L., Velthuis, M. J., Wenzel, J., Winters-Stone, K. M., Wiskemann, J., Berntsen, S. & Buffart, L. M., Feb-2024, In: Scandinavian Journal of Medicine & Science in Sports. 34, 2, 10 p., e14575.

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3 Citations (Scopus)

61 Downloads (Pure)

Effects of Sodium Nitroprusside on Lipopolysaccharide-Induced Inflammation and Disruption of Blood–Brain Barrier

Seoane, N., Picos, A., Moraña-Fernández, S., Schmidt, M., Dolga, A., Campos-Toimil, M. & Viña, D., May-2024, In: Cells. 13, 10, 17 p., 843.

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Novel crosstalk mechanisms between GluA3 and Epac2 in synaptic plasticity and memory in Alzheimer's disease

Zhang, T., Dolga, A. M., Eisel, U. L. M. & Schmidt, M., Feb-2024, In: Neurobiology of Disease. 191, 106389.

Research output: Contribution to journal › Review article › peer-review

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1 Citation (Scopus)

92 Downloads (Pure)

Novel SK channel positive modulators prevent ferroptosis and excitotoxicity in neuronal cells

Zhang, Y., Shaabani, S., Vowinkel, K., Trombetta-Lima, M., Sabogal-Guáqueta, A. M., Chen, T., Hoekstra, J., Lembeck, J., Schmidt, M., Decher, N., Dömling, A. & Dolga, A. M., Feb-2024, In: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 171, 16 p., 116163.

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3 Citations (Scopus)

84 Downloads (Pure)

TNF signaling mediates lipopolysaccharide-induced lung epithelial progenitor cell responses in mouse lung organoids

Li, D., Kortekaas, R. K., Douglas, K. B. I., Douwenga, W., Eisel, U. L. M., Melgert, B. N., Gosens, R. & Schmidt, M., 23-Nov-2024, (E-pub ahead of print) In: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 181, p. 117704 13 p.

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2023

COPD Patients Exhibit Distinct Gene Expression, Accelerated Cellular Aging, and Bias to M2 Macrophages

da Silva, C. O., de Souza Nogueira, J., do Nascimento, A. P., Victoni, T., Bártholo, T. P., da Costa, C. H., Costa, A. M. A., Valença, S. D. S., Schmidt, M. & Porto, L. C., 8-Jun-2023, In: International Journal of Molecular Sciences. 24, 12, 15 p., 9913.

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5 Citations (Scopus)

68 Downloads (Pure)

Modulation of Alveolar Macrophage Activity by Eugenol Attenuates Cigarette-Smoke-Induced Acute Lung Injury in Mice

Barbosa-de-Oliveira, M. C., Oliveira-Melo, P., Gonçalves da Silva, M. H., Andrade Carvalho da Silva, F., Andrade Carvalho da Silva, F., Silva de Araujo, B. V., Franco de Oliveira, M., Tadeu Correia, A., Miyoshi Sakamoto, S., Valença, S. S., Lanzetti, M., Schmidt, M. & Kennedy-Feitosa, E., 11-Jun-2023, In: Antioxidants (Basel, Switzerland). 12, 6, 14 p., 1258.

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2 Citations (Scopus)

51 Downloads (Pure)

Negative modulation of mitochondrial calcium uniporter complex protects neurons against ferroptosis

Marmolejo-Garza, A., Krabbendam, I. E., Luu, M. D. A., Brouwer, F., Trombetta-Lima, M., Unal, O., O’Connor, S. J., Majerníková, N., Elzinga, C. R. S., Mammucari, C., Schmidt, M., Madesh, M., Boddeke, E. & Dolga, A. M., Nov-2023, In: Cell Death and Disease. 14, 11, 15 p., 772.

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15 Citations (Scopus)

89 Downloads (Pure)

Protective effects of caffeine against palmitate-induced lipid toxicity in primary rat hepatocytes is associated with modulation of adenosine receptor A1 signaling

Arroyave-Ospina, J. C., Buist-Homan, M., Schmidt, M. & Moshage, H., Sept-2023, In: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 165, 16 p., 114884.

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5 Citations (Scopus)

101 Downloads (Pure)

The Expression of Epac2 and GluA3 in an Alzheimer's Disease Experimental Model and Postmortem Patient Samples

Zhang, T., Musheshe, N., van der Veen, C. H. J. T. M., Kessels, H. W., Dolga, A., De Deyn, P., Eisel, U. & Schmidt, M., 25-Jul-2023, In: Biomedicines. 11, 8, 16 p., 2096.

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1 Citation (Scopus)

55 Downloads (Pure)

The old second messenger cAMP teams up with novel cell death mechanisms: Potential translational therapeutical benefit for Alzheimer's disease and Parkinson's disease

Zhang, T., Luu, M. D. A., Dolga, A. M., Eisel, U. L. M. & Schmidt, M., 2023, In: Frontiers in Physiology. 14, 19 p., 1207280.

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5 Citations (Scopus)

66 Downloads (Pure)

Unravelling the signaling power of pollutants

Manzano-Covarrubias, A. L., Yan, H., Luu, M. D. A., Gadjdjoe, P. S., Dolga, A. M. & Schmidt, M., Dec-2023, In: Trends in Pharmacological Sciences. 44, 12, p. 917-933 17 p.

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4 Citations (Scopus)

164 Downloads (Pure)

2022

A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration

Wu, X., Bos, I. S. T., Conlon, T. M., Ansari, M., Verschut, V., van der Koog, L., Verkleij, L. A., D'Ambrosi, A., Matveyenko, A., Schiller, H. B., Königshoff, M., Schmidt, M., Kistemaker, L. E. M., Yildirim, A. Ö. & Gosens, R., 22-Mar-2022, In: Science Advances. 8, 12, 14 p., eabj9949 .

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24 Citations (Scopus)

171 Downloads (Pure)

Diesel exhaust particles distort lung epithelial progenitors and their fibroblast niche

Wu, X., Ciminieri, C., Bos, I. S. T., Woest, M. E., D'Ambrosi, A., Wardenaar, R., Spierings, D. C. J., Königshoff, M., Schmidt, M., Kistemaker, L. E. M. & Gosens, R., 15-Jul-2022, In: Environmental Pollution. 305, 12 p., 119292.

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18 Citations (Scopus)

193 Downloads (Pure)

Epithelial 3D-spheroids as a tool to study air pollutant-induced lung pathology

Baarsma, H. A., Van der Veen, C. H. T. J., Lobee, D., Mones, N., Oosterhout, E., Cattani-Cavalieri, I. & Schmidt, M., 1-Apr-2022, In: SLAS discovery : advancing life sciences R & D. 27, 3, p. 185-190 6 p.

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9 Citations (Scopus)

101 Downloads (Pure)

Nanomolar resveratrol reduces early alterations of pancreatitis and pancreatic cancer in pancreatic acinar cells

Pereira, T. M. C., Carvalho, G. R., Luaces-Regueira, M., Bugallo-Casal, A., Iglesias-Mejuto, A., Nugteren, L., Schmidt, M., Viña, D., Vasquez, E. C. & Campos-Toimil, M., Aug-2022, In: Phytomedicine Plus. 2, 3, 8 p., 100301.

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2 Citations (Scopus)

55 Downloads (Pure)

Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity

Musheshe, N., Oun, A., Sabogal-Guáqueta, A. M., Trombetta-Lima, M., Mitchel, S. C., Adzemovic, A., Speek, O., Morra, F., van der Veen, C. H. J. T., Lezoualc'h, F., Cheng, X., Schmidt, M. & Dolga, A. M., 4-Feb-2022, In: Antioxidants (Basel, Switzerland). 11, 2, 20 p., 314.

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21 Citations (Scopus)

126 Downloads (Pure)

2021

Effects of (a Combination of) the Beta2-Adrenoceptor Agonist Indacaterol and the Muscarinic Receptor Antagonist Glycopyrrolate on Intrapulmonary Airway Constriction

Maarsingh, H., Oldenburger, A., Han, B., Zuidhof, A. B., Elzinga, C. R. S., Timens, W., Meurs, H., Sopi, R. B. & Schmidt, M., 2021, In: Cells. 10, 5, 18 p., 1237.

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5 Citations (Scopus)

84 Downloads (Pure)

Elevated cAMP Protects against Diclofenac-Induced Toxicity in Primary Rat Hepatocytes: A Protective Effect Mediated by the Exchange Protein Directly Activated by cAMP/cAMP-Regulated Guanine Nucleotide Exchange Factors

Aguilar Mora, F. A., Musheshe, N., Oun, A., Buist-Homan, M., Lezoualc'h, F., Cheng, X., Schmidt, M. & Moshage, H., 1-Apr-2021, In: Molecular Pharmacology. 99, 4, p. 294-307 14 p.

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8 Citations (Scopus)

105 Downloads (Pure)

Glucosamine protects against neuronal but not vascular damage in experimental diabetic retinopathy

Eshwaran, R., Kolibabka, M., Poschet, G., Jainta, G., Zhao, D., Teuma, L., Murillo, K., Hammes, H.-P., Schmidt, M., Wieland, T. & Feng, Y., Dec-2021, In: Molecular metabolism. 54, 101333.

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10 Citations (Scopus)

96 Downloads (Pure)

Metformin protects against diclofenac-induced toxicity in primary rat hepatocytes by preserving mitochondrial integrity via a pathway involving EPAC

Mora, F. A. A., Musheshe, N., Arroyave Ospina, J. C., Geng, Y., Soto, J. M., Rodrigo, J. A., Alieva, T., Buist-Homan, M., Lezoualc'h, F., Cheng, X., Schmidt, M. & Moshage, H., Nov-2021, In: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 143, 12 p., 112072.

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5 Citations (Scopus)

107 Downloads (Pure)

Refractive index tomography for drug-induced liver injury analysis

Soto, J. M., Aguilar Mora, F. A., Rodrigo, J. A., Geng, Y., Musheshe, N., Buist-Homan, M., Lezoualc’h, F., Cheng, X., Schmidt, M., Moshage, H. & Alieva, T., 2021, Advances in Microscopic Imaging III. Beaurepaire, E., Ben-Yakar, A. & Park, Y. (eds.). SPIE, 119220W. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11922).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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2020

A-Kinase Anchoring Proteins Diminish TGF-β1/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition

Zuo, H., Trombetta-Lima, M., Heijink, I. H., van der Veen, C. H. T. J., Hesse, L., Faber, K. N., Poppinga, W. J., Maarsingh, H., Nikolaev, V. O. & Schmidt, A. M., 3-Feb-2020, In: Cells. 9, 2, 25 p., 356.

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18 Citations (Scopus)

153 Downloads (Pure)

Cigarette smoke exposure alters phosphodiesterases in human structural lung cells

Zuo, H., Faiz, A., van den Berge, M., Mudiyanselage, S. N. H. R., Borghuis, T., Timens, W., Nikolaev, V. O., Burgess, J. K. & Schmidt, M., Jan-2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 1, p. L59-L64 6 p.

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15 Citations (Scopus)

166 Downloads (Pure)

Dimethyl Fumarate Attenuates Lung Inflammation and Oxidative Stress Induced by Chronic Exposure to Diesel Exhaust Particles in Mice

Cattani Pinto Cavalieri, I., Da Maia Valença, H., Moraes, J. A., Brito-Gitirana, L., Romana-Souza, B., Schmidt, M. & Santos Valença, S., 2-Dec-2020, In: International Journal of Molecular Sciences. 21, 24, p. 1-14 14 p., 9658.

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17 Citations (Scopus)

157 Downloads (Pure)

Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle

Baarsma, H. A., Han, B., Poppinga, W. J., Driessen, S., Elzinga, C. R. S., Halayko, A. J., Meurs, H., Maarsingh, H. & Schmidt, M., 9-Apr-2020, In: Frontiers in Cell and Developmental Biology. 8, p. 165 13 p., 165.

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4 Citations (Scopus)

151 Downloads (Pure)

Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity

Chatterjee, A., Eshwaran, R., Poschet, G., Lomada, S., Halawa, M., Wilhelm, K., Schmidt, M., Hammes, H.-P., Wieland, T. & Feng, Y., 2020, In: Cells. 9, 10, 11 p.

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11 Citations (Scopus)

142 Downloads (Pure)

Metformin protects against diclofenac - induced toxicity in primary rat hepatocytes by preserving mitochondrial integrity via an alternative pathway involving epac

EPAC, Nov-2020, In: Hepatology. 72, p. 722A-722A 1 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Nanodomains in cardiopulmonary disorders and the impact of air pollution

Cattani-Cavalieri, I., Valença, S. D. S. & Schmidt, M., 29-Jun-2020, In: Biochemical Society Transactions. 48, 3, p. 799-811 13 p.

Research output: Contribution to journal › Review article › peer-review

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12 Citations (Scopus)

145 Downloads (Pure)

PGE2 and PGI2 restore defective lung epithelial progenitors induced by cigarette smoke

Wu, X., Bos, S., Verkleij, L., D'Ambrosi, A., Schmidt, M., Kiestemaker, L. & Gosens, R., 7-Sept-2020, In: European Respiratory Journal. 56, suppl 64, 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Phosphodiesterase isoforms and cAMP compartments in the development of new therapies for obstructive pulmonary diseases

Schmidt, M., Cattani-Cavalieri, I., Nuñez, F. J. & Ostrom, R. S., Apr-2020, In: Current Opinion in Pharmacology. 51, p. 34-42 9 p.

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22 Citations (Scopus)

160 Downloads (Pure)

PROTECTIVE EFFECT OF CAFFEINE AND PARAXANTHINE AGAINST HEPATOCELLULAR LIPOTOXICITY THROUGH MODULATION OF CYCLIC-AMP SIGNALING

Ospina, J. C. A., Buist-Homan, M., Schmidt, M. & Moshage, H., Nov-2020, In: Hepatology. 72, p. 346A-346A 1 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Role of the Ang2-Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency

Chatterjee, A., Eshwaran, R., Huang, H., Zhao, D., Schmidt, M., Wieland, T. & Feng, Y., 25-May-2020, In: International Journal of Molecular Sciences. 21, 10, 16 p., 3713.

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6 Citations (Scopus)

169 Downloads (Pure)

SK channel activation potentiates auranofin-induced cell death in glio- and neuroblastoma cells

Krabbendam, I. E., Honrath, B., Bothof, L., Silva-Pavez, E., Huerta, H., Peñaranda Fajardo, N. M., Dekker, F., Schmidt, M., Culmsee, C., César Cárdenas, J., Kruyt, F. & Dolga, A. M., Jan-2020, In: Biochemical Pharmacology. 171, 13 p., 113714.

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19 Citations (Scopus)

166 Downloads (Pure)

SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans

Krabbendam, I. E., Honrath, B., Dilberger, B., Iannetti, E. F., Branicky, R. S., Meyer, T., Evers, B., Dekker, F. J., Koopman, W. J. H., Beyrath, J., Bano, D., Schmidt, M., Bakker, B. M., Hekimi, S., Culmsee, C., Eckert, G. P. & Dolga, A. M., 23-Apr-2020, In: Cell death & disease. 11, 4, 18 p., 263.

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33 Citations (Scopus)

201 Downloads (Pure)

2019

5 Citations (Scopus)

cAMP guided his way: a life for G protein-mediated signal transduction and molecular pharmacology-tribute to Karl H. Jakobs

Aktories, K., Gierschik, P., zu Heringdorf, D. M., Schmidt, M., Schultz, G. & Wieland, T., Aug-2019, In: Naunyn-Schmiedebergs Archives of Pharmacology. 392, 8, p. 887-911 25 p.

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7 Citations (Scopus)

146 Downloads (Pure)

Cigarette smoke and diesel particles repress functional responses in lung epithelial progenitors

Schmidt, M., Wu, S., Bos, I. S. T., Kistemaker, L. & Gosens, R., 2019, In: European Respiratory Journal. 54, (suppl 63) PA2437, p. PA2437

Research output: Contribution to journal › Meeting Abstract › Academic

ELEVATED cAMP PROTECTS AGAINST DICLOFENAC-INDUCED TOXICITY IN PRIMARY RAT HEPATOCYTES, A PROTECTIVE EFFECT MEDIATED BY EPACS.

Mora, F. A., Buist-Homan, M., Schmidt, M. & Moshage, H., Oct-2019, In: Hepatology. 70, p. 1220A-1221A 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Function of cyclic AMP scaffolds in obstructive lung disease: Focus on epithelial-to-mesenchymal transition and oxidative stress

Zuo, H., Cattani-Cavalieri, I., Valença, S. S., Musheshe, N. & Schmidt, M., Jul-2019, In: British Journal of Pharmacology. 176, 14, p. 2402-2415 14 p.

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18 Citations (Scopus)

262 Downloads (Pure)

Metabolic escape to glycolysis through SK channel activation inhibits ferroptosis and increases the life span of C. elegans in conditions of heat stress

Dolga, A., Krabbendam, I., Honrath, B., Dilberger, B., Schmidt, M., Eckert, G. & Culmsee, C., Apr-2019, In: FASEB Journal. 33, 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Phosphodiesterases as therapeutic targets for respiratory diseases

Zuo, H., Cattani-Cavalieri, I., Musheshe, N., Nikolaev, V. O. & Schmidt, M., May-2019, In: Pharmacology & Therapeutics. 197, p. 225-242 18 p.

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88 Citations (Scopus)

521 Downloads (Pure)

Revealing the Virulence Potential o f Clinical and Environmental Aspergillus fumigatus Isolates Using Whole-Genome Sequencing

Puertolas-Balint, F., Rossen, J. W. A., dos Santos, C. O., Chlebowicz, M. M. A., Raangs, E. C., van Putten, M. L., Sola-Campoy, P. J., Han, L., Schmidt, M. & Garcia-Cobos, S., 4-Sept-2019, In: Frontiers in Microbiology. 10, 12 p., 1970.

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17 Citations (Scopus)

248 Downloads (Pure)

Martina Schmidt

Research output

Search results