Research output per year
Research output per year
Personal profile
Research interests
Applied Research Activities
Structure-based drug design in human diseases
Basic Research Activities
Structural, biochemical and molecular biology investigation of malarial pathways:
Carbon metabolism in P falciparum
Vitamin biosynthesis in P. falciparum
Method Developments
Crystal identification for structural biology
Biological imaging on free-electron lasers
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Structural characterization and extended substrate scope analysis of two Mg<sup>2+</sup>-dependent O-methyltransferases from bacteria
Sokolova, N., Zhang, L., Deravi, S., Oerlemans, R., Groves, M. R. & Haslinger, K., 29-Jan-2023, (Submitted) BioRxiv, 17 p.Research output: Working paper › Preprint › Academic
File11 Downloads (Pure) -
Actionability of on-target ALK Resistance Mutations in Patients With Non-Small Cell Lung Cancer: Local Experience and Review of the Literature
Koopman, B., Groen, H. J. M., Schuuring, E., Hiltermann, J., Timens, W., den Dunnen, W. F. A., van den Berg, A., ter Elst, A., van Kruchten, M., Kluiver, J., Hiddinga, B., Hijmering-Kappelle, L., Groves, M., Vilachá Madeira R Santos, J., van Kempen, L. & van der Wekken, A. J., Mar-2022, In: Clinical lung cancer. 23, 2, p. e104-e115 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)50 Downloads (Pure) -
Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders
Ulgheri, F., Spanu, P., Deligia, F., Loriga, G., Fuggetta, M. P., de Haan, I., Chandgudge, A., Groves, M. & Domling, A., 5-Feb-2022, In: European Journal of Medicinal Chemistry. 229, 114002.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)21 Downloads (Pure) -
Discovery of Small-Molecule Allosteric Inhibitors of PfATC as Antimalarials
Wang, C., Zhang, B., Krüger, A., Du, X., Visser, L., Dömling, A., Wrenger, C. & Groves, M., 19-Oct-2022, In: Journal of the American Chemical Society. 144, 41, p. 19070–19077 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile23 Downloads (Pure) -
Engineering a plant polyketide synthase for the biosynthesis of methylated flavonoids
Peng, B., Zhang, L., He, S., Oerlemans, R., Quax, W. J., Groves, M. R. & Haslinger, K., 2-Oct-2022, (Submitted) BioRxiv, 27 p.Research output: Working paper › Preprint › Academic
File5 Downloads (Pure)
Activities
- 1 Organising and contributing to an event
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Pharmacy Day 2018
Anna Salvati (Organiser), Amalia Dolga (Organiser), Matthew Groves (Organiser), Klaus Mathwig (Organiser), Peter Horvatovich (Organiser), Wim J. Quax (Organiser), Anne Lexmond (Organiser) & Gillian Dempsey (Organiser)
12-Jun-2018Activity: Organising and attending an event › Organising and contributing to an event › Academic