Research output per year
Research output per year
Personal profile
Research interests
Applied Research Activities
Structure-based drug design in human diseases
Basic Research Activities
Structural, biochemical and molecular biology investigation of malarial pathways:
Carbon metabolism in P falciparum
Vitamin biosynthesis in P. falciparum
Method Developments
Crystal identification for structural biology
Biological imaging on free-electron lasers
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Matthew Groves is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Apo structure of Mycobacterium tuberculosis 1-deoxy-d-xylulose 5-phosphate synthase DXPS: Dynamics and implications for inhibitor design
Gawriljuk, V. O., Alhayek, A., Hirsch, A. K. H. & Groves, M. R., 2-Feb-2025, In: Biochemical and Biophysical Research Communications. 747, p. 151246 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain
Gawriljuk, V. O., Godoy, A. S., Oerlemans, R., Welker, L. A. T., Hirsch, A. K. H. & Groves, M. R., Dec-2024, In: Nature Communications. 15, 1, 11 p., 6642.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)14 Downloads (Pure) -
Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids
Peng, B., Zhang, L., He, S., Oerlemans, R., Quax, W. J., Groves, M. R. & Haslinger, K., 10-Jan-2024, In: Journal of Agricultural and Food Chemistry. 72, 1, p. 529–539 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)99 Downloads (Pure) -
Molecular Tumor Board of the University Medical Center Groningen (UMCG-MTB): outcome of patients with rare or complex mutational profiles receiving MTB-advised targeted therapy
de Jager, V. D., Plomp, P., Paats, M. S., van Helvert, S., Elst, A. T., van den Berg, A., Dubbink, H. J., van Geffen, W. H., Zhang, L., Hendriks, L. E. L., Hiltermann, T. J. N., Hiddinga, B. I., Hijmering-Kappelle, L. B. M., Jalving, M., Kluiver, J., Koopman, B., van Kruchten, M., van der Logt, E. M. J., Piet, B. & van Putten, J. & 10 others, , Nov-2024, In: ESMO Open. 9, 11, 12 p., 103966.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Downloads (Pure) -
Small-Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells
Wang, C., Zhang, B., Cong, Y., Du, X., Chen, S., Visser, L., Ruiz-Moreno, A., Zhang, L., Reggiori, F., Domling , A. & Groves, M. R., 2-Jul-2024, In: ChemMedChem. 19, 13, 8 p., e202300688.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile43 Downloads (Pure)
Activities
- 1 Organising and contributing to an event
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Pharmacy Day 2018
Salvati, A. (Organiser), Dolga, A. (Organiser), Groves, M. (Organiser), Mathwig, K. (Organiser), Horvatovich, P. (Organiser), Quax, W. J. (Organiser), Lexmond, A. (Organiser) & Dempsey, G. (Organiser)
12-Jun-2018Activity: Organising and attending an event › Organising and contributing to an event › Academic
Datasets
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O-methyltransferase from Desulfuromonas acetoxidans
Sokolova, N. (Contributor), Zhang, L. (Contributor), Deravi, S. (Contributor), Oerlemans, R. (Contributor), Groves, M. R. (Contributor) & Haslinger, K. (Contributor), Protein Data Bank (PDB), 5-Apr-2023
DOI: 10.2210/pdb8c9v/pdb
Dataset
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Catechol O-methyltransferase from Streptomyces avermitilis in complex with SAH
Sokolova, N. (Contributor), Zhang, L. (Contributor), Deravi, S. (Contributor), Oerlemans, R. (Contributor), Groves, M. R. (Contributor) & Haslinger, K. (Contributor), Protein Data Bank (PDB), 5-Apr-2023
DOI: 10.2210/pdb8c9s/pdb
Dataset
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Catechol O-methyltransferase from Streptomyces avermitilis
Sokolova, N. (Contributor), Zhang, L. (Contributor), Deravi, S. (Contributor), Oerlemans, R. (Contributor), Groves, M. R. (Contributor) & Haslinger, K. (Contributor), Protein Data Bank (PDB), 5-Apr-2023
DOI: 10.2210/pdb8c9t/pdb
Dataset
Press/Media
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Startup Protyon krijgt subsidie voor levensverlengende software
06/07/2023
1 item of Media coverage
Press/Media: Expert Comment › Popular