Research output per year
Research output per year
- 1 - 50 out of 132 results
Search results
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2025
Apo structure of Mycobacterium tuberculosis 1-deoxy-d-xylulose 5-phosphate synthase DXPS: Dynamics and implications for inhibitor design
Gawriljuk, V. O., Alhayek, A., Hirsch, A. K. H. & Groves, M. R., 2-Feb-2025, In: Biochemical and Biophysical Research Communications. 747, p. 151246 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
2024
Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain
Gawriljuk, V. O., Godoy, A. S., Oerlemans, R., Welker, L. A. T., Hirsch, A. K. H. & Groves, M. R., Dec-2024, In: Nature Communications. 15, 1, 11 p., 6642.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)14 Downloads (Pure) -
Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids
Peng, B., Zhang, L., He, S., Oerlemans, R., Quax, W. J., Groves, M. R. & Haslinger, K., 10-Jan-2024, In: Journal of Agricultural and Food Chemistry. 72, 1, p. 529–539 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)99 Downloads (Pure) -
Molecular Tumor Board of the University Medical Center Groningen (UMCG-MTB): outcome of patients with rare or complex mutational profiles receiving MTB-advised targeted therapy
de Jager, V. D., Plomp, P., Paats, M. S., van Helvert, S., Elst, A. T., van den Berg, A., Dubbink, H. J., van Geffen, W. H., Zhang, L., Hendriks, L. E. L., Hiltermann, T. J. N., Hiddinga, B. I., Hijmering-Kappelle, L. B. M., Jalving, M., Kluiver, J., Koopman, B., van Kruchten, M., van der Logt, E. M. J., Piet, B. & van Putten, J. & 10 others, , Nov-2024, In: ESMO Open. 9, 11, 12 p., 103966.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Downloads (Pure) -
Small-Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells
Wang, C., Zhang, B., Cong, Y., Du, X., Chen, S., Visser, L., Ruiz-Moreno, A., Zhang, L., Reggiori, F., Domling , A. & Groves, M. R., 2-Jul-2024, In: ChemMedChem. 19, 13, 8 p., e202300688.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile43 Downloads (Pure) -
The prediction of treatment outcome in NSCLC patients harboring an EGFR exon 20 mutation using molecular modeling
Zwierenga, F., Zhang, L., Melcr, J., Schuuring, E., van Veggel, B. A. M. H., de Langen, A. J., Groen, H. J. M., Groves, M. R. & van der Wekken, A. J., Nov-2024, In: Lung Cancer. 197, 8 p., 107973.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)6 Downloads (Pure) -
2023
A comprehensive overview of the heterogeneity of EGFR exon 20 variants in NSCLC and (pre)clinical activity to currently available treatments
Zwierenga, F., van Veggel, B. A. M. H., van den Berg, A., Groen, H. J. M., Zhang, L., Groves, M. R., Kok, K., Smit, E. F., Hiltermann, T. J. N., de Langen, A. J. & van der Wekken, A. J., Nov-2023, In: CANCER TREATMENT REVIEWS. 120, 10 p., 102628.Research output: Contribution to journal › Review article › peer-review
Open AccessFile11 Citations (Scopus)140 Downloads (Pure) -
Correction: Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment
Rashidi, F. B., Al-Qahtani, A. D., Bashraheel, S. S., Shaabani, S., Groves, M. R., Dömling, A. & Goda, S. K., 21-Nov-2023, In: PLoS ONE. 18, 11, 2 p., e0294885.Research output: Contribution to journal › Erratum
Open AccessFile36 Downloads (Pure) -
Determination of Binding Sites on Trastuzumab and Pertuzumab to Selective Affimers Using Hydrogen-Deuterium Exchange Mass Spectrometry
Olaleye, O., Graf, C., Spanov, B., Govorukhina, N., Groves, M. R., van de Merbel, N. C. & Bischoff, R., 5-Apr-2023, In: Journal of the American Society for Mass Spectrometry. 34, 4, p. 775-783 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)73 Downloads (Pure) -
Fragment Screening in the Development of a Novel Anti-Malarial
Du, X., Zhang, R. & Groves, M. R., 1-Dec-2023, In: Crystals. 13, 12, 14 p., 1610.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)61 Downloads (Pure) -
Identification and Characterization of a Small Molecule that Activates Thiosulfate Sulfurtransferase and Stimulates Mitochondrial Respiration
Al-Dahmani, Z. M., Hadian, M., Ruiz-Moreno, A. J., Maria, S.-G. A., Batista, F. A., Zhang, R., Luo, Y., Sadremomtaz, A., van der Straat, R., Spoor, M., Dolga, A. M., Dekker, F. J., S S, A. D., van Goor, H. & Groves, M. R., Nov-2023, In: Protein Science. 32, 11, 18 p., e4794.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile50 Downloads (Pure) -
Inhibitors of Aspartate Transcarbamoylase Inhibit Mycobacterium tuberculosis Growth
Du, X., Sonawane, V., Zhang, B., Wang, C., de Ruijter, B., Dömling, A. S. S., Reiling, N. & Groves, M. R., 1-Sept-2023, In: ChemMedChem. 18, 17, 7 p., e202300279.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)55 Downloads (Pure) -
Novel inhibitors of aspartate transcarbamoylase (atcase) and compositions, methods and uses related thereto
Groves, M. R. (Inventor), Wang, C. (Inventor), Lunev, S. (Inventor), Zhang, B. (Inventor), Dömling, A. S. S. (Inventor) & Visser, A. (Inventor), 8-Jun-2023, Patent No. WO2023101556, 2-Dec-2022, Priority date 2-Dec-2021Research output: Patent
Open AccessFile26 Downloads (Pure) -
Structural characterization and extended substrate scope analysis of two Mg<sup>2+</sup>-dependent O-methyltransferases from bacteria
Sokolova, N., Zhang, L., Deravi, S., Oerlemans, R., Groves, M. R. & Haslinger, K., 29-Jan-2023, BioRxiv, 17 p.Research output: Working paper › Preprint › Academic
Open AccessFile54 Downloads (Pure) -
Structural Characterization and Extended Substrate Scope Analysis of Two Mg2+-Dependent O-Methyltransferases from Bacteria**
Sokolova, N., Zhang, L., Deravi, S., Oerlemans, R., Groves, M. R. & Haslinger, K., 2-May-2023, In: ChemBioChem. 24, 9, 11 p., e202300076.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)86 Downloads (Pure) -
Structure of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Synthase in Complex with Butylacetylphosphonate
Gawriljuk, V. O., Oerlemans, R., Gierse, R. M., Jotwani, R., Hirsch, A. K. H. & Groves, M. R., May-2023, In: Crystals. 13, 5, 12 p., 737.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)62 Downloads (Pure) -
Thiosulfate sulfurtransferase deficiency promotes oxidative distress and aberrant NRF2 function in the brain
Luo, Y., Chatre, L., Melhem, S., Al-Dahmani, Z. M., Homer, N. Z. M., Miedema, A., Deelman, L. E., Groves, M. R., Feelisch, M., Morton, N. M., Dolga, A. & van Goor, H., Dec-2023, In: Redox Biology. 68, 12 p., 102965.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)102 Downloads (Pure) -
2022
Actionability of on-target ALK Resistance Mutations in Patients With Non-Small Cell Lung Cancer: Local Experience and Review of the Literature
Koopman, B., Groen, H. J. M., Schuuring, E., Hiltermann, J., Timens, W., den Dunnen, W. F. A., van den Berg, A., ter Elst, A., van Kruchten, M., Kluiver, J., Hiddinga, B., Hijmering-Kappelle, L., Groves, M., Vilachá Madeira R Santos, J., van Kempen, L. & van der Wekken, A. J., Mar-2022, In: Clinical lung cancer. 23, 2, p. e104-e115 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile17 Citations (Scopus)137 Downloads (Pure) -
Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders
Ulgheri, F., Spanu, P., Deligia, F., Loriga, G., Fuggetta, M. P., de Haan, I., Chandgudge, A., Groves, M. & Domling, A., 5-Feb-2022, In: European Journal of Medicinal Chemistry. 229, 114002.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)102 Downloads (Pure) -
Discovery of Small-Molecule Allosteric Inhibitors of PfATC as Antimalarials
Wang, C., Zhang, B., Krüger, A., Du, X., Visser, L., Dömling, A., Wrenger, C. & Groves, M., 19-Oct-2022, In: Journal of the American Chemical Society. 144, 41, p. 19070–19077 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)78 Downloads (Pure) -
Feasibility of Follow-Up Studies and Reclassification in Spinocerebellar Ataxia Gene Variants of Unknown Significance
Ghorbani, F., Alimohamed, M. Z., Vilacha, J. F., Van Dijk, K. K., De Boer-Bergsma, J., Fokkens, M. R., Lemmink, H., Sijmons, R. H., Sikkema-Raddatz, B., Groves, M. R., Verschuuren-Bemelmans, C. C., Verbeek, D. S., Van Diemen, C. C. & Westers, H., 25-Mar-2022, In: Frontiers in Genetics. 13, 13 p., 782685.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)125 Downloads (Pure) -
First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization
Gierse, R. M., Oerlemans, R., Reddem, E. R., Gawriljuk, V. O., Alhayek, A., Baitinger, D., Jakobi, H., Laber, B., Lange, G., Hirsch, A. K. H. & Groves, M. R., 25-Mar-2022, In: Scientific Reports. 12, 13 p., 7221.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Citations (Scopus)95 Downloads (Pure) -
Multicomponent Macrocyclic IL-17a Modifier
Abdelraheem, E., Lubberink, M., Wang, W., Li, J., Reyes Romero, A., Van Der Straat, R., Du, X., Groves, M. & Domling, A., 8-Sept-2022, In: ACS Medicinal Chemistry Letters. 13, 9, p. 1468–1471 4 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)59 Downloads (Pure) -
Novel Highlight in Malarial Drug Discovery: Aspartate Transcarbamoylase
Wang, C., Krüger, A., Du, X., Wrenger, C. & Groves, M. R., 4-Mar-2022, In: Frontiers in Cellular and Infection Microbiology. 12, 9 p., 841833.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)55 Downloads (Pure) -
Synthetic peptides blocking sars-cov-2 (covid-19), and compositions, methods and uses related thereto
Sadremomtaz, A. (Inventor), Groves, M. R. (Inventor), van Goor, H. (Inventor), Doti, N. (Inventor) & Monti, A. (Inventor), 1-Sept-2022, Patent No. WO2022182241, 25-Feb-2022, Priority date 26-Feb-2020Research output: Patent
Open AccessFile22 Downloads (Pure) -
Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike Protein
Sadremomtaz, A., Al-Dahmani, Z. M., Ruiz-Moreno, A. J., Monti, A., Wang, C., Azad, T., Bell, J. C., Doti, N., Velasco-Velázquez, M. A., de Jong, D., de Jonge, J., Smit, J., Dömling, A., van Goor, H. & Groves, M. R., 24-Feb-2022, In: Journal of Medicinal Chemistry. 65, 4, p. 2836-2847 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile24 Citations (Scopus)155 Downloads (Pure) -
Thiosulfate sulfurtransferase prevents hyperglycemic damage to the zebrafish pronephros in an experimental model for diabetes
Al-Dahmani, Z. M., Li, X., Wiggenhauser, L. M., Ott, H., Kruithof, P. D., Lunev, S., A Batista, F., Luo, Y., Dolga, A. M., Morton, N. M., Groves, M. R., Kroll, J. & van Goor, H., 15-Jul-2022, In: Scientific Reports. 12, 1, 7 p., 12077.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)88 Downloads (Pure) -
2021
A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity
Reyes Romero, A., Lunev, S., Popowicz, G. M., Calderone, V., Gentili, M., Sattler, M., Plewka, J., Taube, M., Kozak, M., Holak, T. A., Dömling, A. S. S. & Groves, M. R., 10-Aug-2021, In: Communications biology. 4, 1, 949.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Citations (Scopus)98 Downloads (Pure) -
A synthetic peptide as an allosteric inhibitor of human arginase I and II
Gao, K., Lunev, S., van den Berg, M. P. M., Al-Dahmani, Z. M., Evans, S., Mertens, D. A. L. J., Meurs, H., Gosens, R. & Groves, M. R., 15-Feb-2021, In: Molecular Biology Reports. 48, 2, p. 1959–1966 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)102 Downloads (Pure) -
Combining High-Throughput Synthesis and High-Throughput Protein Crystallography for Accelerated Hit Identification
Sutanto, F., Shaabani, S., Oerlemans, R., Eris, D., Patil, P., Hadian, M., Wang, M., Sharpe, M. E., Groves, M. R. & Dömling, A., 9-Aug-2021, In: Angewandte Chemie (International ed. in English). 60, 33, p. 18231-18239 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile29 Citations (Scopus)92 Downloads (Pure) -
Correction to "Benchmark of Generic Shapes for Macrocycles"
Reyes Romero, A., Ruiz-Moreno, A. J., Groves, M. R., Velasco-Velázquez, M. & Dömling, A., 28-Jun-2021, In: Journal of chemical information and modeling. 61, 6, p. 3158Research output: Contribution to journal › Erratum
Open AccessFile98 Downloads (Pure) -
Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties
Gierse, R. M., Reddem, E. R., Alhayek, A., Baitinger, D., Hamid, Z., Jakobi, H., Laber, B., Lange, G., Hirsch, A. K. H. & Groves, M. R., Feb-2021, In: Biochemical and Biophysical Research Communications. 539, p. 42-47 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Citations (Scopus)222 Downloads (Pure) -
Lipoic Acid Metabolism as a Potential Chemotherapeutic Target Against Plasmodium falciparum and Staphylococcus aureus
Rei Yan, S. L., Wakasuqui, F., Du, X., Groves, M. R. & Wrenger, C., 2021, In: Frontiers in Chemistry. 9, 7 p., 742175.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Citations (Scopus)101 Downloads (Pure) -
Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers
Gao, K., Shaabani, S., Xu, R., Zarganes-Tzitzikas, T., Gao, L., Ahmadianmoghaddam, M., Groves, M. R. & Domling, A., May-2021, In: RSC Medicinal Chemistry. 12, 5, p. 809-818 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Citations (Scopus)94 Downloads (Pure) -
Pharmacological Rationale for Targeting IL-17 in Asthma
Rahmawati, S. F., Te Velde, M., Kerstjens, H. A. M., Dömling, A. S. S., Groves, M. R. & Gosens, R., 30-Aug-2021, In: Frontiers in allergy. 12 p., 694514.Research output: Contribution to journal › Review article › peer-review
Open AccessFile23 Citations (Scopus)88 Downloads (Pure) -
Repurposing the HCV NS3-4A protease drug boceprevir as COVID-19 therapeutics
Oerlemans, R., Ruiz Moreno, A., Cong, Y.-Y., Dinesh Kumar, N., Velasco-Velazquez, M. A., Neochoritis, C. G., Smit, J., Reggiori, F., Groves, M. & Dömling, A., 1-Mar-2021, In: RSC Medicinal Chemistry. 12, 3, p. 370-379 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile62 Citations (Scopus)98 Downloads (Pure) -
The Human Milk Oligosaccharides 3-FL, Lacto-N-Neotetraose, and LDFT Attenuate Tumor Necrosis Factor-alpha Induced Inflammation in Fetal Intestinal Epithelial Cells In Vitro through Shedding or Interacting with Tumor Necrosis Factor Receptor 1
Cheng, L., Kong, C., Wang, W., Groeneveld, A., Nauta, A., Groves, M. R., Kiewiet, M. B. G. & de Vos, P., 3-Mar-2021, In: Molecular Nutrition & Food Research. 9 p., 2000425.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile30 Citations (Scopus)85 Downloads (Pure) -
2020
A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa
Wibowo, J. P., Batista, F. A., van Oosterwijk, N., Groves, M. R., Dekker, F. J. & Quax, W. J., 1-Mar-2020, In: International Journal of Biological Macromolecules. 146, p. 212-221 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile21 Citations (Scopus)356 Downloads (Pure) -
Benchmark of Generic Shapes for Macrocycles
Reyes Romero, A., Ruiz-Moreno, A. J., Groves, M. R., Velasco-Velázquez, M. & Dömling, A., 28-Dec-2020, In: Journal of chemical information and modeling. 60, 12, p. 6298-6313 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Citations (Scopus)319 Downloads (Pure) -
Live and Let Dye: Visualizing the Cellular Compartments of the Malaria Parasite Plasmodium falciparum
Linzke, M., Yan, S. L. R., Tárnok, A., Ulrich, H., Groves, M. R. & Wrenger, C., Jul-2020, In: Cytometry. Part A. 97, 7, p. 694-705 12 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile186 Downloads (Pure) -
Making NSCLC Crystal Clear: How Kinase Structures Revolutionized Lung Cancer Treatment
Vilacha, J. F., Mitchel, S. C., Akele, M. Z., Evans, S. & Groves, M. R., Sept-2020, In: Crystals. 10, 9, p. 1-52 52 p., 725.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Citations (Scopus)184 Downloads (Pure) -
Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the Vascular Endothelial Growth Factor Receptor 1 (VEGFR1D2) for anticancer application
Sadremomtaz, A., Ali, A. M., Jouyandeh, F., Balalaie, S., Navari, R., Broussy, S., Mansouri, K., Groves, M. R. & Asghari, S. M., 1-Dec-2020, In: Signal transduction and targeted therapy. 5, 1, 4 p., 76.Research output: Contribution to journal › Letter › Academic › peer-review
Open AccessFile19 Citations (Scopus)131 Downloads (Pure) -
Molecular target validation of Aspartate Transcarbamoylase from Plasmodium falciparum by Torin 2
Bosch, S., Lunev, S., Batista, F. A., Linzke, M., Kronenberger, T., Dömling, A., Groves, M. R. & Wrenger, C., 8-May-2020, In: ACS Infectious Diseases. 6, 5, p. 986-999 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)129 Downloads (Pure) -
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions
Ricardo, M., Ali, A., Plewka, J., Surmiak, E., Labuzek, B., Neochoritis, C., Atmaj, J., Skalniak, L., Zhang, R., Holak, T., Groves, M., Rivera, D. & Doemling, A., 23-Mar-2020, In: Angewandte Chemie (International ed. in English). 59, 13, p. 5235-5241 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile37 Citations (Scopus)232 Downloads (Pure) -
New directions in antimalarial target validation
Batista, F. A., Gyau, B., Vilacha, J. F., Bosch, S. S., Lunev, S., Wrenger, C. & Groves, M. R., 1-Feb-2020, In: Expert Opinion on Drug Discovery. 15, 2, p. 189-202 14 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile8 Citations (Scopus)287 Downloads (Pure) -
Osimertinib treatment for patients with EGFR exon 20 mutation positive non-small cell lung cancer
van Veggel, B., Madeira R Santos, J. F. V., Hashemi, S. M. S., Paats, M. S., Monkhorst, K., Heideman, D. A. M., Groves, M., Radonic, T., Smit, E. F., Schuuring, E., van der Wekken, A. J. & de Langen, A. J., 1-Mar-2020, In: Lung Cancer. 141, p. 9-13 5 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile76 Citations (Scopus)127 Downloads (Pure) -
Relevance and Effectiveness of Molecular Tumor Board Recommendations for Patients With Non-Small-Cell Lung Cancer With Rare or Complex Mutational Profiles
Koopman, B., van der Wekken, A. J., Elst, ter, A., Hiltermann, J., Vilacha, J. F., Groves, M., van den Berg, A., Hiddinga, B., Hijmering-Kappelle, L., Stigt, J. A., Timens, W., Groen, H. J. M., Schuuring, E. & Kempen, van, L., 23-Apr-2020, In: JCO Precision Oncology. 4, p. 393-410 18 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile34 Citations (Scopus)268 Downloads (Pure) -
TEAD-YAP Interaction Inhibitors and MDM2 Binders from DNA-Encoded Indole-Focused Ugi Peptidomimetics
Kunig, V. B. K., Potowski, M., Akbarzadeh, M., Klika Škopić, M., Dos Santos Smith, D., Arendt, L., Dormuth, I., Adihou, H., Andlovic, B., Karatas, H., Shaabani, S., Zarganes-Tzitzikas, T., Neochoritis, C. G., Zhang, R., Groves, M., Guéret, S. M., Ottmann, C., Rahnenführer, J., Fried, R. & Dömling, A. & 1 others, , 9-Nov-2020, In: Angewandte Chemie (International ed. in English). 59, 46, p. 20338-20342 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile55 Citations (Scopus)80 Downloads (Pure) -
The aroma of TEMED as an activation and stabilizing signal for the antibacterial enzyme HEWL
Seraj, Z., Ahmadian, S., Groves, M. R. & Seyedarabi, A., 19-May-2020, In: PLoS ONE. 15, 5, 17 p., e0232953.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)131 Downloads (Pure) -
Theory and applications of differential scanning fluorimetry in early-stage drug discovery
Gao, K., Oerlemans, R. & Groves, M. R., Feb-2020, In: Biophysical reviews. 12, 1, p. 85-104 20 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile169 Citations (Scopus)845 Downloads (Pure)