PhD project: EEG analysis and personalized intervention studies in mouse models for brain disorders

Disrupted social behaviour is associated with a wide range of neuropsychiatric disorders, and it is often observed independent of and before the onset of other neuropsychiatric symptoms, indicating its potential as an early biomarker for the development of these disorders. Since evolutionarily conserved brain networks and their interplay underlie the expression of social behaviour across the animal kingdom, model organisms can aid in identifying triggers of social dysfunction. My project will involve measuring neural activity as a function of social behaviour in hypersocial mice and mouse models for brain disorders as part of the PRISM2 consortium. Once implemented, this framework will be used to validate lifestyle interventions aimed to reduce the risk of developing a major neuropsychiatric disorder, Alzheimer's disease, as part of the BIRD-NL consortium.