Personal profile
Research interests
I am primarily interested in improving the diagnostic yield of genome sequencing of patients who have a rare disease. I do this by integrating population genetics and transcriptomics.
Education/Academic qualification
PhD student, University of Groningen
27-Aug-2012 → 6-May-2019
Award Date: 6-May-2019
Master Bioinformatics, Vrije Universiteit Amsterdam
2010 → 2012
Bachelor Bioinformatics, Hanze University of Applied Sciences
2006 → 2010
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 8 Decent Work and Economic Growth -
SDG 10 Reduced Inequalities
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Collaborations and top research areas from the last five years
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Improving the diagnostic yield of exome-sequencing by predicting gene-phenotype associations using large-scale gene expression analysis
Deelen, P., van Dam, S., Herkert, J. C., Karjalainen, J. M., Brugge, H., Abbott, K. M., van Diemen, C. C., van der Zwaag, P. A., Gerkes, E. H., Zonneveld-Huijssoon, E., Boer-Bergsma, J. J., Folkertsma, P., Gillett, T., van der Velde, K. J., Kanninga, R., van den Akker, P. C., Jan, S. Z., Hoorntje, E. T., Te Rijdt, W. P. & Vos, Y. J. & 7 others, , 28-Jun-2019, In: Nature Communications. 10, 1, 13 p., 2837.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile94 Citations (Scopus)488 Downloads (Pure) -
Identification of context-dependent expression quantitative trait loci in whole blood
Pital-Zhernakova, D., Deelen, P., Vermaat, M., van Iterson, M., van Galen, M., Arindrarto, W., van 't Hof, P., Mei, H., van Dijk, F., Westra, H.-J., Bonder, M. J., van Rooij, J., Verkerk, M., Jhamai, P. M., Moed, M., Kielbasa, S. M., Bot, J., Nooren, I., Pool, R. & van Dongen, J. & 27 others, , Jan-2017, In: Nature Genetics. 49, 1, p. 139-145 7 p.Research output: Contribution to journal › Letter (Research letter) › Academic › peer-review
303 Citations (Scopus) -
Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels
Deelen, P., Zhernakova, D. V., de Haan, M., van der Sijde, M., Bonder, M. J., Karjalainen, J., van der Velde, K. J., Abbott, K. M., Fu, J., Wijmenga, C., Sinke, R. J., Swertz, M. A. & Franke, L., 27-Mar-2015, In: Genome medicine. 7, 1, 13 p., 30.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile48 Citations (Scopus)687 Downloads (Pure) -
Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking
Lifelines Cohort Study, He, W., van der Most, P. J., Ong, J.-S., Hwang, L.-D., Wu, Y., Magnø, M. S., Vehof, J., Krebs, K., Mauring, L., Õunap, K., Abner, E., Martin, N. G., Plotnikov, D., Jiang, C., Melles, R. B., Gharahkhani, P., Snieder, H., Palumaa, T. & Kaljurand, K. & 5 others, , 23-Aug-2025, In: Nature Communications. 16, 14 p., 7890.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)18 Downloads (Pure) -
Low-cost generation of clinical-grade, layperson-friendly pharmacogenetic passports using oligonucleotide arrays
Lifelines NEXT cohort study, Lanting, P., Warmerdam, R., Slager, J., Brugge, H., Ochi, T., Benjamins, M., Lopera-Maya, E., Jankipersadsing, S., Gelderloos-Arends, J., Teuben, D., Hendriksen, D., Charbon, B., Johansson, L., Munnink, T. O., de Boer-Veger, N., Wilffert, B., Swertz, M., Touw, D. & Deelen, P. & 3 others, , 1-May-2025, In: American Journal of Human Genetics. 112, 5, p. 1015-1028 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)28 Downloads (Pure)
Datasets
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Additional file 3 of Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution
Hofman, B. A. (Contributor), Arindrarto, W. (Contributor), Mei, H. (Contributor), van der Kallen, C. J. H. (Contributor), Schalkwijk, C. G. (Contributor), van Dongen, J. (Contributor), Eline Slagboom (Contributor), van den Berg, L. H. (Contributor), Luijk, R. (Contributor), Jansen, R. (Contributor), 't Hoen, P. A. C. (Contributor), Lakenberg, N. (Contributor), van Galen, M. (Contributor), Heijmans, B. T. (Contributor), Verbiest, M. (Contributor), Wijmenga, C. (Contributor), Bonder, M. J. (Contributor), Beekman, M. (Contributor), Kielbasa, S. M. (Contributor), van 't Hof, P. (Contributor), van Rooij, J. (Contributor), van Heemst, D. (Contributor), Deelen, P. (Contributor), Uitterlinden, A. G. (Contributor), Pool, R. (Contributor), Vermaat, M. (Contributor), Verkerk, M. (Contributor), van Duijn, C. M. (Contributor), Isaacs, A. (Contributor), Moed, M. (Contributor), van Iterson, M. (Contributor), Stehouwer, C. D. A. (Contributor), Tigchelaar - Feenstra, E. (Contributor), Suchiman, H. E. D. (Contributor), Zhernakova, D. (Contributor), van Greevenbroek, M. M. J. (Contributor), van der Breggen, R. (Contributor), Swertz, M. (Contributor), Veldink, J. H. (Contributor), Boomsma, D. I. (Contributor), Bot, J. (Contributor), van Meurs, J. (Contributor), Jhamai, P. M. (Contributor), Deelen, J. (Contributor), 't Hoen, P.-B. (Contributor), Zhernakova, S. (Contributor), Nooren, I. (Contributor), Hottenga, J. J. (Contributor), Franke, L. (Contributor), van Zwet, E. W. (Contributor) & van Dijk, F. (Contributor), University of Groningen, 28-Jan-2017
DOI: 10.6084/m9.figshare.c.3676579_d4.v1, https://doi.org/10.6084%2Fm9.figshare.c.3676579_d4.v1
Dataset
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Additional file 6 of Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution
't Hoen, P. A. C. (Contributor), Verbiest, M. (Contributor), Vermaat, M. (Contributor), Tigchelaar - Feenstra, E. (Contributor), Verkerk, M. (Contributor), Heijmans, B. T. (Contributor), van der Breggen, R. (Contributor), Nooren, I. (Contributor), Isaacs, A. (Contributor), 't Hoen, P.-B. (Contributor), Lakenberg, N. (Contributor), Mei, H. (Contributor), van Dijk, F. (Contributor), Wijmenga, C. (Contributor), Zhernakova, D. (Contributor), van Heemst, D. (Contributor), Boomsma, D. I. (Contributor), Stehouwer, C. D. A. (Contributor), Deelen, J. (Contributor), Bonder, M. J. (Contributor), Hofman, B. A. (Contributor), Schalkwijk, C. G. (Contributor), Bot, J. (Contributor), Zhernakova, S. (Contributor), Kielbasa, S. M. (Contributor), van Duijn, C. M. (Contributor), Franke, L. (Contributor), Uitterlinden, A. G. (Contributor), Beekman, M. (Contributor), Jhamai, P. M. (Contributor), Moed, M. (Contributor), Luijk, R. (Contributor), van Meurs, J. (Contributor), Arindrarto, W. (Contributor), van Zwet, E. W. (Contributor), Jansen, R. (Contributor), Swertz, M. (Contributor), van 't Hof, P. (Contributor), van Rooij, J. (Contributor), van Dongen, J. (Contributor), van den Berg, L. H. (Contributor), Veldink, J. H. (Contributor), Eline Slagboom (Contributor), van Greevenbroek, M. M. J. (Contributor), Deelen, P. (Contributor), Suchiman, H. E. D. (Contributor), van Iterson, M. (Contributor), van der Kallen, C. J. H. (Contributor), Hottenga, J. J. (Contributor), Pool, R. (Contributor) & van Galen, M. (Contributor), University of Groningen, 28-Jan-2017
DOI: 10.6084/m9.figshare.c.3676579_d7.v1, https://doi.org/10.6084%2Fm9.figshare.c.3676579_d7.v1
Dataset
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Additional file 5 of Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution
Wijmenga, C. (Contributor), Verbiest, M. (Contributor), Hofman, B. A. (Contributor), Vermaat, M. (Contributor), Nooren, I. (Contributor), Mei, H. (Contributor), Eline Slagboom (Contributor), van Iterson, M. (Contributor), Veldink, J. H. (Contributor), van Galen, M. (Contributor), van 't Hof, P. (Contributor), van Meurs, J. (Contributor), 't Hoen, P.-B. (Contributor), van Heemst, D. (Contributor), Franke, L. (Contributor), Zhernakova, S. (Contributor), Moed, M. (Contributor), Verkerk, M. (Contributor), Pool, R. (Contributor), Beekman, M. (Contributor), van Dijk, F. (Contributor), van den Berg, L. H. (Contributor), Zhernakova, D. (Contributor), Bot, J. (Contributor), Hottenga, J. J. (Contributor), Lakenberg, N. (Contributor), van der Breggen, R. (Contributor), van der Kallen, C. J. H. (Contributor), Bonder, M. J. (Contributor), Deelen, P. (Contributor), Jansen, R. (Contributor), Schalkwijk, C. G. (Contributor), Jhamai, P. M. (Contributor), Swertz, M. (Contributor), Tigchelaar - Feenstra, E. (Contributor), Isaacs, A. (Contributor), Kielbasa, S. M. (Contributor), Luijk, R. (Contributor), Uitterlinden, A. G. (Contributor), van Dongen, J. (Contributor), van Greevenbroek, M. M. J. (Contributor), Arindrarto, W. (Contributor), van Rooij, J. (Contributor), Heijmans, B. T. (Contributor), Stehouwer, C. D. A. (Contributor), van Zwet, E. W. (Contributor), 't Hoen, P. A. C. (Contributor), Suchiman, H. E. D. (Contributor), Deelen, J. (Contributor), van Duijn, C. M. (Contributor) & Boomsma, D. I. (Contributor), University of Groningen, 28-Jan-2017
DOI: 10.6084/m9.figshare.c.3676579_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3676579_d1.v1
Dataset
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Additional file 7 of Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution
van Galen, M. (Contributor), Luijk, R. (Contributor), van der Kallen, C. J. H. (Contributor), 't Hoen, P. A. C. (Contributor), van der Breggen, R. (Contributor), van Dongen, J. (Contributor), van Heemst, D. (Contributor), van Iterson, M. (Contributor), van Rooij, J. (Contributor), Lakenberg, N. (Contributor), van 't Hof, P. (Contributor), Verkerk, M. (Contributor), Vermaat, M. (Contributor), Beekman, M. (Contributor), Verbiest, M. (Contributor), Boomsma, D. I. (Contributor), Jhamai, P. M. (Contributor), Bot, J. (Contributor), Suchiman, H. E. D. (Contributor), Franke, L. (Contributor), Heijmans, B. T. (Contributor), Hottenga, J. J. (Contributor), Moed, M. (Contributor), Deelen, J. (Contributor), Deelen, P. (Contributor), Nooren, I. (Contributor), Jansen, R. (Contributor), Swertz, M. (Contributor), 't Hoen, P.-B. (Contributor), Zhernakova, S. (Contributor), van Dijk, F. (Contributor), Pool, R. (Contributor), Hofman, B. A. (Contributor), van den Berg, L. H. (Contributor), Uitterlinden, A. G. (Contributor), Bonder, M. J. (Contributor), Kielbasa, S. M. (Contributor), van Meurs, J. (Contributor), Eline Slagboom (Contributor), Stehouwer, C. D. A. (Contributor), Tigchelaar - Feenstra, E. (Contributor), Zhernakova, D. (Contributor), Schalkwijk, C. G. (Contributor), Mei, H. (Contributor), Arindrarto, W. (Contributor), Wijmenga, C. (Contributor), van Zwet, E. W. (Contributor), van Duijn, C. M. (Contributor), Veldink, J. H. (Contributor), Isaacs, A. (Contributor) & van Greevenbroek, M. M. J. (Contributor), University of Groningen, 28-Jan-2017
DOI: 10.6084/m9.figshare.c.3676579_d5.v1, https://doi.org/10.6084%2Fm9.figshare.c.3676579_d5.v1
Dataset
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Additional file 4 of Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution
van der Breggen, R. (Contributor), Hofman, B. A. (Contributor), Pool, R. (Contributor), Nooren, I. (Contributor), Deelen, P. (Contributor), Vermaat, M. (Contributor), Zhernakova, S. (Contributor), van Zwet, E. W. (Contributor), Heijmans, B. T. (Contributor), Moed, M. (Contributor), van den Berg, L. H. (Contributor), Arindrarto, W. (Contributor), Suchiman, H. E. D. (Contributor), Zhernakova, D. (Contributor), van 't Hof, P. (Contributor), van Dongen, J. (Contributor), Bonder, M. J. (Contributor), Tigchelaar - Feenstra, E. (Contributor), Schalkwijk, C. G. (Contributor), Kielbasa, S. M. (Contributor), van Iterson, M. (Contributor), van der Kallen, C. J. H. (Contributor), van Duijn, C. M. (Contributor), Deelen, J. (Contributor), Veldink, J. H. (Contributor), van Heemst, D. (Contributor), 't Hoen, P.-B. (Contributor), Mei, H. (Contributor), Jhamai, P. M. (Contributor), van Dijk, F. (Contributor), Jansen, R. (Contributor), Eline Slagboom (Contributor), Luijk, R. (Contributor), Wijmenga, C. (Contributor), van Rooij, J. (Contributor), Bot, J. (Contributor), Lakenberg, N. (Contributor), van Galen, M. (Contributor), Isaacs, A. (Contributor), Boomsma, D. I. (Contributor), 't Hoen, P. A. C. (Contributor), van Meurs, J. (Contributor), Verkerk, M. (Contributor), Stehouwer, C. D. A. (Contributor), Beekman, M. (Contributor), Swertz, M. (Contributor), Uitterlinden, A. G. (Contributor), Franke, L. (Contributor), Hottenga, J. J. (Contributor), Verbiest, M. (Contributor) & van Greevenbroek, M. M. J. (Contributor), University of Groningen, 28-Jan-2017
DOI: 10.6084/m9.figshare.c.3676579_d6.v1, https://doi.org/10.6084%2Fm9.figshare.c.3676579_d6.v1
Dataset
Press/Media
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Did you follow COVID lockdown rules? Whether or not you did is partially driven by your DNA
22/08/2022
1 Media contribution
Press/Media: Expert Comment › Popular
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COVID-19: Whether you followed lockdown rules may have been influenced by your genetics
23/05/2022
1 Media contribution
Press/Media: Expert Comment › Popular
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Whether you followed lockdown rules may have been influenced by your genetics – new research
22/05/2022
1 Media contribution
Press/Media: Expert Comment › Popular
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Followed lockdown rules? It may have been your genetics, says new research
22/05/2022
1 Media contribution
Press/Media: Expert Comment › Popular
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Genetic regulation of blood cells: Proximity of a gene to a genetic change plays an important role
Bonder, M. J., Claringbould, A. & Deelen, P.
22/09/2021
1 item of Media coverage
Press/Media: Research › Popular