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  • 2022

    A genome-wide association study of total child psychiatric problems scores

    Neumann, A., Nolte, I. M., Pappa, I., Ahluwalia, T. S., Pettersson, E., Rodriguez, A., Whitehouse, A., van Beijsterveldt, C. E. M., Benyamin, B., Hammerschlag, A. R., Helmer, Q., Karhunen, V., Krapohl, E., Lu, Y., van der Most, P. J., Palviainen, T., St Pourcain, B., Seppälä, I., Suarez, A., Vilor-Tejedor, N. & 41 others, Tiesler, C. M. T., Wang, C., Wills, A., Zhou, A., Alemany, S., Bisgaard, H., Bønnelykke, K., Davies, G. E., Hakulinen, C., Henders, A. K., Hyppönen, E., Stokholm, J., Bartels, M., Hottenga, J-J., Heinrich, J., Hewitt, J., Keltikangas-Järvinen, L., Korhonen, T., Kaprio, J., Lahti, J., Lahti-Pulkkinen, M., Lehtimäki, T., Middeldorp, C. M., Najman, J. M., Pennell, C., Power, C., Oldehinkel, A. J., Plomin, R., Räikkönen, K., Raitakari, O. T., Rimfeld, K., Sass, L., Snieder, H., Standl, M., Sunyer, J., Williams, G. M., Bakermans-Kranenburg, M. J., Boomsma, D. I., van IJzendoorn, M. H., Hartman, C. A. & Tiemeier, H., 22-Aug-2022, In: PLoS ONE. 17, 8, 23 p., e0273116.

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  • A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

    Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Million Veterans Program, Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K-H. H., Ntalla, I., Hui, Q. & 31 others, Klarin, D., Hilliard, A. T., Wang, Z., Xue, C., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Akiyama, M., Zhao, W., Zhao, J-H., Le, P., Verweij, N., Benjamins, J. W., Wang, Y. X., van der Most, P. J., van der Laan, S. W., Wang, J-S., Asselbergs, F. W., Oldehinkel, A. J., Snieder, H., Penninx, B., Kumari, M., van der Harst, P., Huang, W., Kim, Y. J., de Vries, P. S. & Zhu, X., 4-Aug-2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 22 p.

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  • Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

    Lifelines Cohort Study, VA Million Veteran Program, DiscovEHR/MyCode , Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J-F., Sieber, K. B., Horn, K., Li, M. & 34 others, Scholz, M., Cocca, M., Wuttke, M., van der Most, P. J., Yang, Q., Ghasemi, S., Nutile, T., Li, Y., Pontali, G., Günther, F., Dehghan, A., Correa, A., Parsa, A., Feresin, A., de Vries, A. P. J., Zonderman, A. B., Smith, A. V., Oldehinkel, A. J., De Grandi, A., Rosenkranz, A. R., Franke, A., Teren, A., Penninx, B. W. J. H., Hartman, C. A., Snieder, H., Nolte, I. M., de Borst, M. H., Verweij, N., van der Harst, P., Gansevoort, R. T., Bakker, S. J. L., Huang, W., Wang, Y. X. & Heid, I. M., 13-Jun-2022, In: Communications biology. 5, 1, 20 p., 580.

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  • Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population

    de Haan, A., Ahmadizar, F., van der Most, P. J., Thio, C. H. L., Kamali, Z., Ani, A., Ghanbari, M., Chaker, L., van Meurs, J., Ikram, M. K., van Goor, H., Bakker, S. J. L., van der Harst, P., Snieder, H., Kavousi, M., Pasch, A., Eijgelsheim, M. & de Borst, M. H., 14-Jan-2022, In: Frontiers in cardiovascular medicine. 8, 11 p., 809717.

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  • Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

    Lifelines Cohort Study, Gorski, M., Rasheed, H., Teumer, A., Thomas, L. F., Graham, S. E., Sveinbjornsson, G., Winkler, T. W., Günther, F., Stark, K. J., Chai, J-F., Tayo, B. O., Wuttke, M., Li, Y., Tin, A., Ahluwalia, T. S., Ärnlöv, J., Åsvold, B. O., Bakker, S. J. L., Banas, B. & 31 others, Bansal, N., Biggs, M. L., Biino, G., Böhnke, M., Boerwinkle, E., Bottinger, E. P., Brenner, H., Brumpton, B., Carroll, R. J., Chaker, L., Chalmers, J., Chee, M-L., Chee, M-L., Cheng, C-Y., Chu, A. Y., Ciullo, M., Cocca, M., Cook, J. P., Coresh, J., Cusi, D., de Borst, M. H., Degenhardt, F., Eckardt, K-U., Gansevoort, R. T., Nolte, I. M., Penninx, B. W. J. H., Snieder, H., Thio, C. H. L., van der Harst, P., van der Most, P. J. & Verweij, N., 15-Jun-2022, (E-pub ahead of print) In: Kidney International.

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  • Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Lifelines Cohort Study, Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B. & 31 others, Feitosa, M. F., Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Lagou, V., Van der Most, P. J., Van Vliet-Ostaptchouk, J. V., Zhao, J-H., Zhao, W., Bruinenberg, M., Hartman, C. A., Nolte, I. M., Smith, A., Oldehinkel, A. J., Penninx, B. W. J. H. & Snieder, H., Sep-2022, In: Nature genetics. 54, p. 1332–1344 25 p.

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  • Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies

    Harlow, C. E., Gandawijaya, J., Bamford, R. A., Martin, E. R., Wood, A. R., van der Most, P. J., Tanaka, T., Leonard, H. L., Etheridge, A. S., Innocenti, F., Beaumont, R. N., Tyrrell, J., Nalls, M. A., Simonsick, E. M., Garimella, P. S., Shiroma, E. J., Verweij, N., van der Meer, P., Gansevoort, R. T., Snieder, H. & 13 others, Gallins, P. J., Jima, D. D., Wright, F., Zhou, Y., Ferrucci, L., Bandinelli, S., Hernandez, D. G., van der Harst, P., Patel, V. V., Waterworth, D. M., Chu, A. Y., Oguro-Ando, A. & Frayling, T. M., 1-Sep-2022, In: American Journal of Human Genetics. 109, 9, p. 1638-1652 15 p.

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  • Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    23andMe Research Team, Social Science Genetic Association Consortium, Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C. & 5 others, Campbell, A., Porteous, D. J., Freese, J., Herd, P. & Young, A. I., Apr-2022, In: Nature genetics. 54, 4, p. 437-449 13 p.

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  • 2021

    A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans

    Bejar, C. A., Goyal, S., Afzal, S., Mangino, M., Zhou, A., van der Most, P. J., Bao, Y., Gupta, V., Smart, M. C., Walia, G. K., Verweij, N., Power, C., Prabhakaran, D., Singh, J. R., Mehra, N. K., Wander, G. S., Ralhan, S., Kinra, S., Kumari, M., de Borst, M. H. & 5 others, Hypponen, E., Spector, T. D., Nordestgaard, B. G., Blackett, P. R. & Sanghera, D. K., 27-Jul-2021, In: Nutrition journal. 20, 1, 11 p., 71.

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  • Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes

    Lifelines Cohort Study, VA Million Veteran Program, Pazoki, R., Vujkovic, M., Elliott, J., Evangelou, E., Gill, D., Ghanbari, M., van der Most, P. J., Pinto, R. C., Wielscher, M., Farlik, M., Zuber, V., de Knegt, R. J., Snieder, H., Uitterlinden, A. G., Lynch, J. A., Jiang, X., Said, S., Kaplan, D. E. & 17 others, Lee, K. M., Serper, M., Carr, R. M., Tsao, P. S., Atkinson, S. R., Dehghan, A., Tzoulaki, I., Ikram, M. A., Herzig, K. H., Järvelin, M. R., Alizadeh, B. Z., O'Donnell, C. J., Saleheen, D., Voight, B. F., Chang, K. M., Thursz, M. R. & Elliott, P., 10-May-2021, In: Nature Communications. 12, 1, 12 p., 2579.

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  • Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

    23andMe Research Team, Meddens, S. F. W., de Vlaming, R., Bowers, P., Burik, C. A. P., Linnér, R. K., Lee, C., Okbay, A., Turley, P., Rietveld, C. A., Fontana, M. A., Ghanbari, M., Imamura, F., McMahon, G., van der Most, P. J., Voortman, T., Wade, K. H., Anderson, E. L., Braun, K. V. E., Emmett, P. M. & 24 others, Esko, T., Gonzalez, J. R., Kiefte-de Jong, J. C., Langenberg, C., Luan, J., Muka, T., Ring, S., Rivadeneira, F., Snieder, H., van Rooij, F. J. A., Wolffenbuttel, B. H. R., Smith, G. D., Franco, O. H., Forouhi, N. G., Ikram, M. A., Uitterlinden, A. G., van Vliet-Ostaptchouk, J. V., Wareham, N. J., Cesarini, D., Harden, K. P., Lee, J. J., Benjamin, D. J., Chow, C. C. & Koellinger, P. D., Jun-2021, In: Molecular Psychiatry. 26, p. 2056–2069 14 p.

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  • GWASinspector: comprehensive quality control of genome-wide association study results

    Ani, A., van der Most, P. J., Snieder, H., Vaez, A. & Nolte, I. M., 1-Jan-2021, In: Bioinformatics (Oxford, England). 37, 1, p. 129-130 2 p.

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  • Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

    Lifelines Cohort Study, Regeneron Genetics Ctr, Gorski, M., Jung, B., Li, Y., Matias-Garcia, P. R., Wuttke, M., Coassin, S., Thio, C. H. L., Kleber, M. E., Winkler, T. W., Wanner, V., Chai, J-F., Chu, A. Y., Cocca, M., Feitosa, M. F., Ghasemi, S., Hoppmann, A., Horn, K., Li, M. & 32 others, Nutile, T., Scholz, M., Sieber, K. B., Teumer, A., Tin, A., Wang, J., Tayo, B. O., Ahluwalia, T. S., Almgren, P., Bakker, S. J. L., Banas, B., Bansal, N., Biggs, M. L., Boerwinkle, E., Bottinger, E. P., Brenner, H., Carroll, R. J., Chalmers, J., Chee, M-L., Chee, M-L., Cheng, C-Y., Coresh, J., de Borst, M. H., Degenhardt, F., Gansevoort, R. T., Nolte, I. M., Penninx, B. W. J. H., van der Harst, P., van der Most, P. J., Verweij, N., Zhang, Y. & Snieder, H., Apr-2021, In: Kidney International. 99, 4, p. 926-939 14 p.

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  • Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits

    Lifelines Cohort Study, Sun, D., Richard, M., Musani, S. K., Sung, Y. J., Winkler, T. W., Schwander, K., Chai, J. F., Guo, X., Kilpeläinen, T. O., Vojinovic, D., Aschard, H., Bartz, T. M., Bielak, L. F., Brown, M. R., Chitrala, K., Hartwig, F. P., Horimoto, A. R. V. R., Liu, Y., Manning, A. K. & 32 others, Noordam, R., Smith, A. V., Harris, S. E., Kühnel, B., Lyytikäinen, L-P., Nolte, I. M., Rauramaa, R., van der Most, P. J., Wang, R., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Arking, D. E., Arnett, D. K., Barac, A., Boerwinkle, E., Broeckel, U., Chakravarti, A., Chen, Y-D. I., Cupples, L. A., Davigulus, M. L., de Las Fuentes, L., de Mutsert, R., de Vries, P. S., Hartman, C. C. A., Zhao, W., Oldehinkel, A. J., Penninx, B. W. J. H., Snieder, H., Wang, Y-X. & Fornage, M., 14-Jan-2021, In: HGG advances. 2, 1

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  • Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

    Wang, H., Noordam, R., Cade, B. E., Schwander, K., Winkler, T. W., Lee, J., Sung, Y. J., Bentley, A. R., Manning, A. K., Aschard, H., Kilpeläinen, T. O., Ilkov, M., Brown, M. R., Horimoto, A. R., Richard, M., Bartz, T. M., Vojinovic, D., Lim, E., Nierenberg, J. L., Liu, Y. & 105 others, Chitrala, K., Rankinen, T., Musani, S. K., Franceschini, N., Rauramaa, R., Alver, M., Zee, P. C., Harris, S. E., van der Most, P. J., Nolte, I. M., Munroe, P. B., Palmer, N. D., Kühnel, B., Weiss, S., Wen, W., Hall, K. A., Lyytikäinen, L-P., O'Connell, J., Eiriksdottir, G., Launer, L. J., de Vries, P. S., Arking, D. E., Chen, H., Boerwinkle, E., Krieger, J. E., Schreiner, P. J., Sidney, S., Shikany, J. M., Rice, K., Chen, Y-D. I., Gharib, S. A., Bis, J. C., Luik, A. I., Ikram, M. A., Uitterlinden, A. G., Amin, N., Xu, H., Levy, D., He, J., Lohman, K. K., Zonderman, A. B., Rice, T. K., Sims, M., Wilson, G., Sofer, T., Rich, S. S., Palmas, W., Yao, J., Guo, X., Rotter, J. I., Biermasz, N. R., Mook-Kanamori, D. O., Martin, L. W., Barac, A., Wallace, R. B., Gottlieb, D. J., Komulainen, P., Heikkinen, S., Mägi, R., Milani, L., Metspalu, A., Starr, J. M., Milaneschi, Y., Waken, R. J., Gao, C., Waldenberger, M., Peters, A., Strauch, K., Meitinger, T., Roenneberg, T., Völker, U., Dörr, M., Shu, X-O., Mukherjee, S., Hillman, D. R., Kähönen, M., Wagenknecht, L. E., Gieger, C., Grabe, H. J., Zheng, W., Palmer, L. J., Lehtimäki, T., Gudnason, V., Morrison, A. C., Pereira, A. C., Fornage, M., Psaty, B. M., van Duijn, C. M., Liu, C-T., Kelly, T. N., Evans, M. K., Bouchard, C., Fox, E. R., Kooperberg, C., Zhu, X., Lakka, T. A., Esko, T., North, K. E., Deary, I. J., Snieder, H., Penninx, B. W. J. H., Gauderman, W. J., Rao, D. C., Redline, S. & van Heemst, D., 15-Apr-2021, In: Molecular Psychiatry. 12 p.

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  • Search for a Functional Genetic Variant Mimicking the Effect of SGLT2 Inhibitor Treatment

    Wang, S., Said, M. A., Groot, H. E., Most, P. J. V. D., Thio, C. H. L., Vegte, Y. J. V. D., Verweij, N., Snieder, H. & Harst, P. V. D., Aug-2021, In: Genes. 12, 8, p. 1-13 13 p., 1174.

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  • The power of genetic diversity in genome-wide association studies of lipids

    VA Million Veteran Program, Graham, S. E., Clarke, S. L., Wu, K-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., Verma, A. & 31 others, Trivedi, B., Martin, H. C., Hunt, K. A., Hui, Q., Klarin, D., Zhu, X., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Akiyama, M., Sakaue, S., Terao, C., Zhao, W., Zhao, J-H., Verweij, N., Benjamins, J. W., Le, P., Wang, Y. X., van der Most, P. J., van der Laan, S. W., Asselbergs, F. W., Oldehinkel, A. J., Snieder, H., Penninx, B., Kumari, M., van der Harst, P., Huang, W., Kim, Y. J. & de Vries, P. S., 23-Dec-2021, In: Nature. 600, p. 675-679 25 p.

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  • The trans-ancestral genomic architecture of glycemic traits

    Lifelines Cohort Study, Metaanal Glucose Insulin Related, Chen, J., Spracklen, C. N., Marenne, G., Varshney, A., Corbin, L. J., Luan, J., Willems, S. M., Wu, Y., Zhang, X., Horikoshi, M., Boutin, T. S., Magi, R., Waage, J., Li-Gao, R., Chan, K. H. K., Yao, J., Anasanti, M. D., Chu, A. Y. & 33 others, Claringbould, A., Heikkinen, J., Hong, J., Hottenga, J-J., Huo, S., Kaakinen, M. A., Louie, T., Maerz, W., Moreno-Macias, H., Ndungu, A., Nelson, S. C., Nolte, I. M., North, K. E., Demirkan, A., Kim, Y. J., Sanna, S., Smith, A. V., van der Most, P. J., Verweij, N., Xie, T., Zhao, J-H., Zhao, W., Bakker, S. J. L., Hartman, C. A., Raven, D., van Vliet-Ostaptchouk, J. V., Boomsma, D. I., Huang, W., Kumari, M., Snieder, H., van der Harst, P., Wang, Y. X. & Oldehinkel, A. J., Jun-2021, In: Nature Genetics. 53, p. 840-860 41 p.

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  • 2020

    Genetic Risk Scores for Complex Disease Traits in Youth

    Xie, T., Wang, B., Nolte, I. M., van der Most, P. J., Oldehinkel, A. J., Hartman, C. A. & Snieder, H., Aug-2020, In: Circulation. Genomic and precision medicine. 13, 4, p. 212-221 10 p., e002775.

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  • Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure

    Huang, Y., Ollikainen, M., Muniandy, M., Zhang, T., van Dongen, J., Hao, G., van Der Most, P. J., Pan, Y., Pervjakova, N., Sun, Y., Hui, Q., Lahti, J., Fraszczyk, E., Lu, X., Sun, D., Richard, M. A., Willemsen, G., Heikkila, K., Leach, I. M., Mononen, N. & 30 others, Kahonen, M., Hurme, M. A., Raitakari, O. T., Drake, A. J., Perola, M., Nuotio, M-L., Huang, Y., Khulan, B., Raikkonen, K., Wolffenbuttel, B. H. R., Zhernakova, A., Fu, J., Zhu, H., Dong, Y., van Vliet-Ostaptchouk, J. V., Franke, L., Eriksson, J. G., Fornage, M., Milani, L., Lehtimaki, T., Vaccarino, V., Boomsma, D., van Der Harst, P., de Geus, E. J. C., Salomaa, V., Li, S., Chen, W., Su, S., Wilson, J. & Snieder, H., Jul-2020, In: Hypertension. 76, 1, p. 195-205 11 p.

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  • Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

    Early Growth Genetics Consortium, Vogelezang, S., Bradfield, J. P., Ahluwalia, T. S., Curtin, J. A., Lakka, T. A., Grarup, N., Scholz, M., van der Most, P. J., Monnereau, C., Stergiakouli, E., Heiskala, A., Horikoshi, M., Fedko, I. O., Vilor-Tejedor, N., Cousminer, D. L., Standl, M., Wang, C. A., Viikari, J., Geller, F. & 31 others, Íñiguez, C., Pitkänen, N., Chesi, A., Bacelis, J., Yengo, L., Torrent, M., Ntalla, I., Helgeland, Ø., Selzam, S., Vonk, J. M., Zafarmand, M. H., Heude, B., Farooqi, I. S., Alyass, A., Beaumont, R. N., Have, C. T., Rzehak, P., Bilbao, J. R., Schnurr, T. M., Barroso, I., Bønnelykke, K., Beilin, L. J., Carstensen, L., Charles, M-A., Chawes, B., Clément, K., Closa-Monasterolo, R., Custovic, A., Reijneveld, S. A., Koppelman, G. H. & Snieder, H., 12-Oct-2020, In: PLoS genetics. 16, 10, 26 p., e1008718.

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  • Post-GWAS analysis of six substance use traits improves the identification and functional interpretation of genetic risk loci

    Int Cannabis Consortium, 1-Jan-2020, In: Drug and Alcohol Dependence. 206, 9 p., 107703.

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  • 2019

    A catalog of genetic loci associated with kidney function from analyses of a million individuals

    Lifelines Cohort Study, Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., Wang, L., Chu, A. Y., Hoppmann, A., Kirsten, H., Giri, A., Chai, J-F., Sveinbjornsson, G., Tayo, B. O., Nutile, T., Fuchsberger, C., Marten, J., Cocca, M. & 32 others, Ghasemi, S., Xu, Y., Horn, K., Noce, D., Van der Most, P. J., Sedaghat, S., Yu, Z., Akiyama, M., Afaq, S., Ahluwalia, T. S., Almgren, P., Amin, N., Arnlov, J., Bakker, S. J. L., Bansal, N., De Borst, M. H., De Vries, A. P. J., Demirkan, A., Gansevoort, R. T., Hartman, C. A., Huang, W., Nolte, I. M., Oldehinkel, A. J., Penninx, B. W. J. H., Prins, B. P., Smith, A. V., Van der Harst, P., Verweij, N., Wang, Y. X., Xu, L., Snieder, H. & Thio, C. H. L., Jun-2019, In: Nature Genetics. 51, 6, p. 957-+ 19 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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    228 Citations (Scopus)
  • A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

    Lifelines Cohort Study, 1-Aug-2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

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  • A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

    EAGLE-ADHD Consortium, May-2019, In: Behavior Genetics. 49, 3, p. 270-285 16 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    3 Citations (Scopus)
  • Associations of autozygosity with a broad range of human phenotypes

    Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M. & 416 others, Baumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J-F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-Salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M-L., Chen, G., Chen, Y-D. I., Chen, Z., Chiu, Y-F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., van Heel, D. A., Hirata, M., Höfer, I., Hsiung, C. A., Huang, J., Hung, Y-J., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K-T., Khor, C. C., de Kleijn, D. P. V., Koh, W-P., Kolcic, I., Kraft, P., Krämer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I-T., Lee, W-J., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A. W., Manunta, P., Másson, G., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P-E., Moreno-Macías, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., de Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Pálsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-Murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Sala, C. F., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-Khayat, B., Sennblad, B., van Setten, J., Sever, P. J., Sheu, W. H-H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stančáková, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y-C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusié-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Völker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J-M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., van den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C-Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C-K., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., De Jager, P. L., Johannesson, M., Johansson, Å., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., März, W., Matullo, G., McCarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-Kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O'connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., Den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E-S., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D-A., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T-Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 31-Oct-2019, In: Nature Communications. 10, 1, 17 p., 4957.

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  • Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    ADHD Working Grp Psychiat Genomics, Early Lifecourse Genetic, 23andMe Res Team, Demontis, D., Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., Belliveau, R., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Cerrato, F., Chambert, K., Churchhouse, C., Dumont, A., Eriksson, N., Gandal, M., Goldstein, J. I. & 33 others, Grasby, K. L., Grove, J., Gudmundsson, O. O., Hansen, C. S., Hauberg, M. E., Hollegaard, M. V., Howrigan, D. P., Huang, H., Maller, J. B., Martin, A. R., Martin, N. G., Moran, J., Pallesen, J., Palmer, D. S., Pedersen, C. B., Pedersen, M. G., Poterba, T., Poulsen, J. B., Ripke, S., Robinson, E. B., Satterstrom, F. K., Stefansson, H., Stevens, C., Turley, P., Walters, G. B., Won, H., Wright, M. J., Nguyen, T. T., Davies, G. E., Hartman, C. A., Nolte, I. M., Ormel, J. & van der Most, P. J., Jan-2019, In: Nature Genetics. 51, 1, p. 63-+ 16 p.

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    754 Citations (Scopus)
  • Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

    Noordam, R., Young, W. J., Salman, R., Kanters, J. K., van den Berg, M. E., van Heemst, D., Lin, H. J., Barreto, S. M., Biggs, M. L., Biino, G., Catamo, E., Concas, M. P., Ding, J., Evans, D. S., Foco, L., Grarup, N., Lyytikäinen, L-P., Mangino, M., Mei, H., van der Most, P. J. & 83 others, Müller-Nurasyid, M., Nelson, C. P., Qian, Y., Repetto, L., Said, M. A., Shah, N., Schramm, K., Vidigal, P. G., Weiss, S., Yao, J., Zilhao, N. R., Brody, J. A., Braund, P. S., Brumat, M., Campana, E., Christofidou, P., Caulfield, M. J., De Grandi, A., Dominiczak, A. F., Doney, A. S. F., Eiriksdottir, G., Ellervik, C., Giatti, L., Gögele, M., Graff, C., Guo, X., van der Harst, P., Joshi, P. K., Kähönen, M., Kestenbaum, B., Lima-Costa, M. F., Linneberg, A., Maan, A. C., Meitinger, T., Padmanabhan, S., Pattaro, C., Peters, A., Petersmann, A., Sever, P., Sinner, M. F., Shen, X., Stanton, A., Strauch, K., Soliman, E. Z., Tarasov, K. V., Taylor, K. D., Thio, C. H. L., Uitterlinden, A. G., Vaccargiu, S., Waldenberger, M., Robino, A., Correa, A., Cucca, F., Cummings, S. R., Dörr, M., Girotto, G., Gudnason, V., Hansen, T., Heckbert, S. R., Juhl, C. R., Kääb, S., Lehtimäki, T., Liu, Y., Lotufo, P. A., Palmer, C. N. A., Pirastu, M., Pramstaller, P. P., Ribeiro, A. L. P., Rotter, J. I., Samani, N. J., Snieder, H., Spector, T. D., Stricker, B. H., Verweij, N., Wilson, J. F., Wilson, J. G., Jukema, J. W., Tinker, A., Newton-Cheh, C. H., Sotoodehnia, N., Mook-Kanamori, D. O., Munroe, P. B. & Warren, H. R., 25-Jun-2019, In: Journal of the American College of Cardiology. 73, 24, p. 3118-3131 14 p.

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    18 Citations (Scopus)
  • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    23and Me Res Team, eQTLgen Consortium, Int Cannabis Consortium & Soc Sci Genetic Association Con, Feb-2019, In: Nature Genetics. 51, 2, p. 245-257 16 p.

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    218 Citations (Scopus)
  • Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

    Teumer, A., Li, Y., Ghasemi, S., Prins, B. P., Wuttke, M., Hermle, T., Giri, A., Sieber, K. B., Qiu, C., Kirsten, H., Tin, A., Chu, A. Y., Bansal, N., Feitosa, M. F., Wang, L., Chai, J-F., Cocca, M., Fuchsberger, C., Gorski, M., Hoppmann, A. & 166 others, Horn, K., Li, M., Marten, J., Noce, D., Nutile, T., Sedaghat, S., Sveinbjornsson, G., Tayo, B. O., Van der Most, P. J., Xu, Y., Yu, Z., Gerstner, L., Arnlov, J., Bakker, S. J. L., Baptista, D., Biggs, M. L., Boerwinkle, E., Brenner, H., Burkhardt, R., Carroll, R. J., Chee, M-L., Chee, M-L., Chen, M., Cheng, C-Y., Cook, J. P., Coresh, J., Corre, T., Danesh, J., de Borst, M. H., De Grandi, A., de Mutsert, R., de Vries, A. P. J., Degenhardt, F., Dittrich, K., Divers, J., Eckardt, K-U., Ehret, G., Endlich, K., Felix, J. F., Franco, O. H., Franke, A., Freedman, B. I., Freitag-Wolf, S., Gansevoort, R. T., Giedraitis, V., Gogele, M., Grundner-Culemann, F., Gudbjartsson, D. F., Gudnason, V., Hamet, P., Harris, T. B., Hicks, A. A., Holm, H., Foo, V. H. X., Hwang, S-J., Ikram, M. A., Ingelsson, E., Jaddoe, V. W. V., Jakobsdottir, J., Josyula, N. S., Jung, B., Kahonen, M., Khor, C-C., Kiess, W., Koenig, W., Koerner, A., Kovacs, P., Kramer, H., Kraemer, B. K., Kronenberg, F., Lange, L. A., Langefeld, C. D., Lee, J. J-M., Lehtimaki, T., Lieb, W., Lim, S-C., Lind, L., Lindgren, C. M., Liu, J., Loeffler, M., Lyytikainen, L-P., Mahajan, A., Maranville, J. C., Mascalzoni, D., McMullen, B., Meisinger, C., Meitinger, T., Miliku, K., Mook-Kanamori, D. O., Mueller-Nurasyid, M., Mychaleckyj, J. C., Nauck, M., Nikus, K., Ning, B., Noordam, R., Connell, J. O., Olafsson, I., Palmer, N. D., Peters, A., Podgornaia, A. I., Ponte, B., Poulain, T., Pramstaller, P. P., Rabelink, T. J., Raffield, L. M., Reilly, D. F., Rettig, R., Rheinberger, M., Rice, K. M., Rivadeneira, F., Runz, H., Ryan, K. A., Sabanayagam, C., Saum, K-U., Schoettker, B., Shaffer, C. M., Shi, Y., Smith, A. V., Strauch, K., Stumvoll, M., Sun, B. B., Szymczak, S., Tai, E-S., Tan, N. Y. Q., Taylor, K. D., Teren, A., Tham, Y-C., Thiery, J., Thio, C. H. L., Thomsen, H., Thorsteinsdottir, U., Tonjes, A., Tremblay, J., Uitterlinden, A. G., Van der Harst, P., Verweij, N., Vogelezang, S., Voelker, U., Waldenberger, M., Wang, C., Wilson, O. D., Wong, C., Wong, T-Y., Yang, Q., Yasuda, M., Akilesh, S., Bochud, M., Boeger, C. A., Devuyst, O., Edwards, T. L., Ho, K., Morris, A. P., Parsa, A., Pendergrass, S. A., Psaty, B. M., Rotter, J. I., Stefansson, K., Wilson, J. G., Susztak, K., Snieder, H., Heid, I. M., Scholz, M., Butterworth, A. S., Hung, A. M., Pattaro, C. & Koettgen, A., 11-Sep-2019, In: Nature Communications. 10, 1, p. 4130 19 p., 4130.

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  • Genome-Wide Association Scan of Serum Urea in European Populations Identifies Two Novel Loci

    Lifelines Cohort Study group, Thio, C. H. L., Reznichenko, A., van der Most, P. J., Kamali, Z., Vaez, A., Smit, J. H., Penninx, B. W. J. H., Haller, T., Mihailov, E., Metspalu, A., Damman, J., de Borst, M. H., van der Harst, P., Verweij, N., Navis, G. J., Gansevoort, R. T., Nolte, I. M. & Snieder, H., 2019, In: American Journal of Nephrology. 49, 3, p. 193-202 10 p.

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  • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

    InterAct Consortium & LifeLines Cohort Study Grp, Jun-2019, In: American Journal of Epidemiology. 188, 6, p. 1033-1054 22 p.

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  • Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

    COGENT-Kidney Consortium, EPIC-InterAct Consortium, Understanding Soc Sci Grp & Lifelines Cohort, Apr-2019, In: Nature Genetics. 51, 4, p. 636-+ 16 p.

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    59 Citations (Scopus)
  • Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

    Kilpelainen, T. O., Nolte, I. M., van der Most, P. J., Verweij, N., Snieder, H., van der Ende, M. Y., Oldehinkel, A. J., van der Harst, P., Van Vliet-Ostaptchouk, J. V., Lifelines Cohort Study & Wang, Y. X., 22-Jan-2019, In: Nature Communications. 10, 1, 11 p., 376.

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  • Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

    German Chronic Kidney Disease Study, Tin, A., Marten, J., Halperin Kuhns, V. L., Li, Y., Wuttke, M., Kirsten, H., Sieber, K. B., Qiu, C., Gorski, M., Yu, Z., Giri, A., Sveinbjornsson, G., Li, M., Chu, A. Y., Hoppmann, A., O'Connor, L. J., Prins, B., Nutile, T., Noce, D. & 31 others, Akiyama, M., Cocca, M., Ghasemi, S., van der Most, P. J., Horn, K., Xu, Y., Fuchsberger, C., Sedaghat, S., Afaq, S., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boerwinkle, E., Bottinger, E. P., Boutin, T. S., Brumat, M., de Borst, M. H., de Vries, A. P. J., Gansevoort, R. T., Huang, W., Nolte, I. M., Penninx, B. W. J. H., Smith, A. V., van der Harst, P., Verweij, N. & Snieder, H., Oct-2019, In: Nature Genetics. 51, 10, p. 1459-1474 22 p.

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  • The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

    EAGLE Consortium, EGG Consortium, EGG Membership & EAGLE Membership, Mar-2019, In: European Journal of Epidemiology. 34, 3, p. 279-300 22 p.

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  • The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

    UK Ireland Renal Transplant Consortium, Stapleton, C. P., Heinzel, A., Guan, W., van der Most, P. J., van Setten, J., Lord, G. M., Keating, B. J., Israni, A. K., de Borst, M. H., Bakker, S. J. L., Snieder, H., Weale, M. E., Delaney, F., Hernandez-Fuentes, M. P., Reindl-Schwaighofer, R., Oberbauer, R., Jacobson, P. A., Mark, P. B., Chapman, F. A. & 16 others, Phelan, P. J., Kennedy, C., Sexton, D., Murray, S., Jardine, A., Traynor, J. P., McKnight, A. J., Maxwell, A. P., Smyth, L. J., Oetting, W. S., Matas, A. J., Mannon, R. B., Schladt, D. P., Iklé, D. N., Cavalleri, G. L. & Conlon, P. J., Aug-2019, In: American Journal of Transplantation. 19, 8, p. 2262-2273 12 p.

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    5 Citations (Scopus)
  • Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

    COGENT Consortium, Morris, A. P., Le, T. H., Wu, H., Akbarov, A., van der Most, P. J., Hemani, G., Smith, G. D., Mahajan, A., Gaulton, K. J., Nadkarni, G. N., Valladares-Salgado, A., Wacher-Rodarte, N., Mychaleckyj, J. C., Dueker, N. D., Guo, X., Hai, Y., Haessler, J., Kamatani, Y., Stilp, A. M. & 31 others, Zhu, G., Cook, J. P., Arnlov, J., Blanton, S. H., de Borst, M. H., Bottinger, E. P., Buchanan, T. A., Cechova, S., Charchar, F. J., Chu, P-L., Damman, J., Eales, J., Gharavi, A. G., Giedraitis, V., Heath, A. C., Ipp, E., Kiryluk, K., Kramer, H. J., Kubo, M., Larsson, A., Lindgren, C. M., Lu, Y., Madden, P. A. F., Montgomery, G. W., Papanicolaou, G. J., Raffel, L. J., Sacco, R. L., Sanchez, E., Stark, H., Sundstrom, J. & Snieder, H., 3-Jan-2019, In: Nature Communications. 10, 1, 14 p., 29.

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  • 2018

    A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

    Sung, Y. J., Winkler, T. W., de Las Fuentes, L., Bentley, A. R., Brown, M. R., Kraja, A. T., Schwander, K., Ntalla, I., Guo, X., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Feitosa, M. F., Kilpeläinen, T. O., Richard, M. A. & 31 others, Noordam, R., Aslibekyan, S., Aschard, H., Bartz, T. M., Dorajoo, R., Liu, Y., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Warren, H. R., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., van der Most, P. J., Snieder, H., Oldehinkel, A. J., van der Harst, P. & CHARGE Neurology Working Group, 1-Mar-2018, In: American Journal of Human Genetics. 102, 3, p. 375-400 26 p.

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    58 Citations (Scopus)
  • 5 Citations (Scopus)
  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Million Veteran Program, Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., Karaman, I., Ng, F. L., Evangelou, M., Witkowska, K., Tzanis, E., Hellwege, J. N., Giri, A., Velez Edwards, D. R., Sun, Y. V., Cho, K. & 31 others, Gaziano, J. M., Wilson, P. W. F., Tsao, P. S., Kovesdy, C. P., Esko, T., Mägi, R., Milani, L., Almgren, P., Boutin, T., Debette, S., Ding, J., Giulianini, F., Holliday, E. G., Jackson, A. U., Li-Gao, R., Prins, B. P., Verweij, N., Zhao, J-H., Borst, M. H. D., Hartman, C. A., Lin, L., Nolte, I. M., Oldehinkel, A. J., Penninx, B. W. J. H., Riese, H., Smith, A. V., Snieder, H., Swertz, M. A., Vaez, A., van der Most, P. J. & van der Harst, P., Oct-2018, In: Nature Genetics. 50, 10, p. 1412-+ 17 p.

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    395 Citations (Scopus)
  • Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

    Lifelines Cohort Study, Ligthart, S., Vaez, A., Võsa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Macé, A., Sidore, C., Trompet, S. & 16 others, Mangino, M., Sabater-Lleal, M., Kemp, J. P., Abbasi, A., Kacprowski, T., Verweij, N., Smith, A. V., Huang, T., Marzi, C., Feitosa, M. F., Lohman, K. K., Kleber, M. E., Milaneschi, Y., Huq, M., Zhao, J. H. & Amini, M., 1-Nov-2018, In: American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

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    134 Citations (Scopus)
  • Genome-wide association meta-analysis of age at first cannabis use

    Minică, C. C., Verweij, K. J. H., van der Most, P. J., Mbarek, H., Bernard, M., van Eijk, K. R., Lind, P. A., Liu, M. Z., Maciejewski, D. F., Palviainen, T., Sánchez-Mora, C., Sherva, R., Taylor, M., Walters, R. K., Abdellaoui, A., Bigdeli, T. B., Branje, S. J. T., Brown, S. A., Casas, M., Corley, R. P. & 30 others, Smith, G. D., Davies, G. E., Ehli, E. A., Farrer, L., Fedko, I. O., Garcia-Martínez, I., Gordon, S. D., Hartman, C. A., Heath, A. C., Hickie, I. B., Hickman, M., Hopfer, C. J., Hottenga, J. J., Kahn, R. S., Kaprio, J., Korhonen, T., Kranzler, H. R., Krauter, K., van Lier, P. A. C., Madden, P. A. F., Medland, S. E., Neale, M. C., Meeus, W. H. J., Montgomery, G. W., Nolte, I. M., Oldehinkel, A. J., Pausova, Z., Ramos-Quiroga, J. A., Boks, M. P. & Snieder, H., Nov-2018, In: Addiction. 113, 11, p. 2073-2086 14 p.

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    18 Citations (Scopus)
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  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    InterAct Consortium, 18-Jun-2018, In: PLoS ONE. 13, 6, 36 p., 0198166.

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  • 5 Citations (Scopus)
    332 Downloads (Pure)
  • 2017

    1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

    Gorski, M., Van der Most, P. J., Teumer, A., Chu, A. Y., Li, M., Mijatovic, V., Nolte, I. M., Cocca, M., Taliun, D., Gomez, F., Li, Y., Tayo, B., Tin, A., Feitosa, M. F., Aspelund, T., Attia, J., Biffar, R., Bochud, M., Boerwinkle, E., Borecki, I. & 106 others, Bottinger, E. P., Chen, M-H., Chouraki, V., Ciullo, M., Coresh, J., Cornelis, M. C., Curhan, G. C., d'Adamo, A. P., Dehghan, A., Dengler, L., Ding, J., Eiriksdottir, G., Endlich, K., Enroth, S., Esko, T., Franco, O. H., Gasparini, P., Gieger, C., Girotto, G., Gottesman, O., Gudnason, V., Gyllensten, U., Hancock, S. J., Harris, T. B., Helmer, C., Hoellerer, S., Hofer, E., Hofman, A., Holliday, E. G., Homuth, G., Hu, F. B., Huth, C., Hutri-Kahonen, N., Hwang, S-J., Imboden, M., Johansson, A., Kahonen, M., Koenig, W., Kraemer, H., Kramer, B. K., Kumar, A., Kutalik, Z., Lambert, J-C., Launer, L. J., Lehtimaki, T., de Borst, M., Navis, G., Swertz, M., Liu, Y., Lohman, K., Loos, R. J. F., Lu, Y., Lyytikainen, L-P., McEvoy, M. A., Meisinger, C., Meitinger, T., Metspalu, A., Metzger, M., Mihailov, E., Mitchell, P., Nauck, M., Oldehinkel, A. J., Olden, M., Penninx, B. W. J. H., Pistis, G., Pramstaller, P. P., Probst-Hensch, N., Raitakari, O. T., Rettig, R., Ridker, P. M., Rivadeneira, F., Robino, A., Rosas, S. E., Ruderfer, D., Ruggiero, D., Saba, Y., Sala, C., Schmidt, H., Schmidt, R., Scott, R. J., Sedaghat, S., Smith, A. V., Sorice, R., Stengel, B., Stracke, S., Strauch, K., Toniolo, D., Uitterlinden, A. G., Ulivi, S., Viikari, J. S., Voelker, U., Vollenweider, P., Voelzke, H., Vuckovic, D., Waldenberger, M., Wang, J. J., Yang, Q., Chasman, D. I., Tromp, G., Snieder, H., Heid, I. M., Fox, C. S., Koettgen, A., Pattaro, C., Boeger, C. A. & Fuchsberger, C., 28-Apr-2017, In: Scientific Reports. 7, 10 p., 45040.

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  • CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

    Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C. & 86 others, van der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M-L., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, T., Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z., 29-Sep-2017, In: Nature Communications. 8, 1, 11 p., 744.

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  • Genetic loci associated with heart rate variability and their effects on cardiac disease risk

    Nolte, I. M., Munoz, M. L., Tragante, V., Amare, A. T., Jansen, R., Vaez, A., von der Heyde, B., Avery, C. L., Bis, J. C., Dierckx, B., van Dongen, J., Gogarten, S. M., Goyette, P., Hernesniemi, J., Huikari, V., Hwang, S-J., Jaju, D., Kerr, K. F., Kluttig, A., Krijthe, B. P. & 144 others, Kumar, J., van der Laan, S. W., Lyytikainen, L-P., Maihofer, A. X., Minassian, A., van der Most, P. J., Mueller-Nurasyid, M., Nivard, M., Salvi, E., Stewart, J. D., Thayer, J. F., Verweij, N., Wong, A., Zabaneh, D., Zafarmand, M. H., Abdellaoui, A., Albarwani, S., Albert, C., Alonso, A., Ashar, F., Auvinen, J., Axelsson, T., Baker, D. G., de Bakker, P. I. W., Barcella, M., Bayoumi, R., Bieringa, R. J., Boomsma, D., Boucher, G., Britton, A. R., Christophersen, I. E., Dietrich, A., Ehret, G. B., Ellinor, P. T., Eskola, M., Felix, J. F., Floras, J. S., Franco, O. H., Friberg, P., Gademan, M. G. J., Geyer, M. A., Giedraitis, V., Hartman, C. A., Hemerich, D., Hofman, A., Hottenga, J-J., Huikuri, H., Hutri-Kahonen, N., Jouven, X., Junttila, J., Juonala, M., Kiviniemi, A. M., Kors, J. A., Kumari, M., Kuznetsova, T., Laurie, C. C., Lefrandt, J. D., Li, Y., Li, Y., Liao, D., Limacher, M. C., Lin, H. J., Lindgren, C. M., Lubitz, S. A., Mahajan, A., McKnight, B., zu Schwabedissen, H. M., Milaneschi, Y., Mononen, N., Morris, A. P., Nalls, M. A., Navis, G., Neijts, M., Nikus, K., North, K. E., O'Connor, D. T., Ormel, J., Perz, S., Peters, A., Psaty, B. M., Raitakari, O. T., Risbrough, V. B., Sinner, M. F., Siscovick, D., Smit, J. H., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Staessen, J. A., Stein, P. K., Stilp, A. M., Stolarz-Skrzypek, K., Strauch, K., Sundstrom, J., Swenne, C. A., Syvanen, A-C., Tardif, J-C., Taylor, K. D., Teumer, A., Thornton, T. A., Tinker, L. E., Uitterlinden, A. G., van Setten, J., Voss, A., Waldenberger, M., Wilhelmsen, K. C., Willemsen, G., Wong, Q., Zhang, Z-M., Zonderman, A. B., Cusi, D., Evans, M. K., Greiser, H. K., van der Harst, P., Hassan, M., Ingelsson, E., Jarvelin, M-R., Kaab, S., Kahonen, M., Kivimaki, M., Kooperberg, C., Kuh, D., Lehtimaki, T., Lind, L., Nievergelt, C. M., O'Donnell, C. J., Oldehinkel, A. J., Penninx, B., Reiner, A. P., Riese, H., van Roon, A. M., Rioux, J. D., Rotter, J. I., Sofer, T., Stricker, B. H., Tiemeier, H., Vrijkotte, T. G. M., Asselbergs, F. W., Brundel, B. J. J. M., Heckbert, S. R., Whitsel, E. A., den Hoed, M., Snieder, H. & de Geus, E. J. C., 14-Jun-2017, In: Nature Communications. 8, 15 p., 15805.

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  • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg, J., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., de Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J-O., Jarvelin, M-R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-Donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. B., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M-C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y-D., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., Faire, U. D., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H-J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J., Loos, R. J. F., Kilpeläinen, T. O., Liu, C-T., Borecki, I. B., North, K. E. & Cupples, L. A., 26-Apr-2017, In: Nature Communications. 8, 19 p., 14977.

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