Research output per year
Research output per year
Personal profile
External positions
Group leader, Max Planck Inst for Molecular Physiology, Dortmund
Sept-1993 → May-1999
post-doc, University of Leiden
Sept-1991 → Aug-1993
PhD student, Ecole Polytechnique, Dept de Biochimie, Palaiseau
Jan-1986 → Aug-1991
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos
Chen, D., Osipyan, A., Adriana, J., Kader, M., Gureev, M., Knol, C. W. J., Sigmund, M. C., Xiao, Z., van der Wouden, P. E., Cool, R. H., Poelarends, G. J. & Dekker, F. J., 13-Jul-2023, In: Journal of Medicinal Chemistry. 66, 13, p. 8767-8781 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
4-Iodopyrimidine labeling reveals nuclear translocation and nuclease activity for both MIF and MIF2
Xiao, Z., Chen, D., Mulder, F., Song, S., van der Wouden, P. E., Cool, R. H., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 3-Jan-2022, In: Chemistry. 28, 1, e202103030.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)83 Downloads (Pure) -
The Role of Tryptophan in π Interactions in Proteins: An Experimental Approach
Shao, J., Kuiper, B. P., Thunnissen, A-M. W. H., Cool, R. H., Zhou, L., Huang, C., Dijkstra, B. W. & Broos, J., Sept-2022, In: Journal of the American Chemical Society. 144, 30, p. 13815-13822 8 p., 04986.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)49 Downloads (Pure) -
Thieno[2,3- d]pyrimidine-2,4(1 H,3 H)-dione Derivative Inhibits d -Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells
Xiao, Z., Osipyan, A., Song, S., Chen, D., Schut, R. A., van Merkerk, R., van der Wouden, P. E., Cool, R. H., Quax, W. J., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 10-Feb-2022, In: Journal of Medicinal Chemistry. 65, 3, p. 2059-2077Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Citations (Scopus)47 Downloads (Pure) -
D-dopachrome tautomerase contributes to lung epithelial repair via ACKR3-dependent Akt signaling
Song, S., Liu, B., Habibie, H., Van den Bor, J., Smit, M. J., Gosens, R., Wu, X., Brandsma, C-A., Cool, R. H., Haisma, H. J., Poelarends, G. J. & Melgert, B. N., 5-Sept-2021, In: European Respiratory Journal. 58, 3 p.Research output: Contribution to journal › Meeting Abstract › Academic
Datasets
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CCDC 1575884: Experimental Crystal Structure Determination
Go, T. K. (Contributor), Wapenaar, H. (Contributor), Wang, K. (Contributor), Neochoritis, D. (Contributor), Zarganis Tzitzikas, T. (Contributor), Proietti, G. (Contributor), Eleftheriadis, N. (Contributor), Kurpiewska, K. (Contributor), Kalinowska-Tłuścik, J. (Contributor), Cool, R. (Contributor), Poelarends, G. (Contributor), Dömling, A. (Contributor) & Dekker, F. (Contributor), University of Groningen, 21-Sept-2017
DOI: 10.5517/ccdc.csd.cc1pwtzc
Dataset