Personal profile

Research interests

The research of Prof. Dr. S. Schmidt exploits the powerful reactivity and selectivity of enzymes from secondary metabolite pathways for the production of natural products and their analogs for pharmaceutical applications. One of the main areas of interest is the identification, characterization and the engineering of Rieske non-heme iron oxygenases for their application in biocatalytic reactions towards pharmaceuticals and/or precursors thereof. Along this line, the outstanding reactivities of these biocatalysts are exploited in synthetic metabolic pathways and (chemo)enzymatic cascade reactions for the production of complex compounds from simple precursors. The Schmidt group is thereby using state-of-the-art synthetic biology tools for the design and assembly of artificial metabolic pathways, and is developing new methodologies for the genetic engineering of several chassis strains. Finally, the Schmidt group aims at the development of new concepts for electron transfer pathways in microorganisms, and is developing concepts to optimize electron transfer chains in multi-component oxidoreductases. By expanding our knowledge on the parameters determining efficient electron transfer and thus catalysis, it is expected that this will increase the broad applicability of multi-component oxidoreductases relying on complex electron transfer mechanisms.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy
  • SDG 9 - Industry, Innovation, and Infrastructure
  • SDG 12 - Responsible Consumption and Production
  • SDG 13 - Climate Action
  • SDG 15 - Life on Land

Education/Academic qualification

PhD student, Institute of Biochemistry, University of Greifswald, Greifswald, Germany.

1-Oct-201231-Oct-2015

Award Date: 27-Oct-2015

Group Leader, Graz University of Technology

1-Feb-201731-Mar-2020

Postdoctoral Researcher, Delft University of Technology

1-Dec-201531-Jan-2017

Studies in Biochemistry, Institute of Biochemistry, University of Greifswald, Greifswald, Germany.

Oct-2007Sept-2012

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