Research output per year
Research output per year
Personal profile
Research interests
Epithelial stem cells in disease contexts, with a primary basis on salivary gland stem cells. Disease contexts include the autoimmune disaease primary Sjögren's syndrome (pSS), radaition damage, medication-indcued xerostomia and check point inhibitor-indcued xerostomia. Development of iPS technology for generation of new salivary glands for patients with xerostomia. Cite-Seq analysis of salivary gland biopsies to elucidate potential early events in pSS. In vitro modelling of lymphoepithelial lesions in primary Sjögren's syndrome. Devlopment of senescence markers as surrogates for SG function in pSS. Development of in vitro cell culture models of vasculitis. Functionality of stem cells in other autoimmune idseases, for example Crohns and SLE. Development of mouse model of pSS, based on epithelial cell dysfunction.
Education/Academic qualification
King's College Hospital
10-Sep-2005 → 31-Aug-2009
Award Date: 20-Aug-2010
Univ Leeds, University of Leeds
1-Sep-2000 → 1-Jun-2004
Award Date: 23-Jul-2004
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Senescent progenitor cells in the skin of patients with cutaneous lupus erythematosus
Wang, X., Diercks, G., Lambers, W. M., Westra, J., Bootsma, H., Kroese, F. G. M., de Leeuw, K. & Pringle, S., Mar-2022, In: Journal of Investigative Dermatology. 142, 3 part B, p. 976-980.e2 7 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review
Open AccessFile5 Downloads (Pure) -
A Distinct Macrophage Subset Mediating Tissue Destruction and Neovascularization in Giant Cell Arteritis: Implication of the YKL-40/Interleukin-13 Receptor alpha 2 Axis
Sleen, Y. V., Jiemy, W. F., Pringle, S., Geest, K. S. M. V. D., Abdulahad, W. H., Sandovici, M., Brouwer, E., Heeringa, P. & Boots, A. M. H., Dec-2021, In: Arthritis & Rheumatology. 73, 12, p. 2327-2337 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile14 Downloads (Pure) -
A distinct subset of YKL-40 expressing macrophages drive tissue destruction and neovascularisation in giant cell arteritis
Van Sleen, Y., Jiemy, W. F., Pringle, S., Van der Geest, K. S. M., Abdulahad, W. H., Sandovici, M., Brouwer, E., Heeringa, P. & Boots, A. M. H., Aug-2021, In: European Journal of Immunology. 51, p. 265-265 1 p.Research output: Contribution to journal › Meeting Abstract › Academic
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beta-Adrenergic signaling induces Notch-mediated salivary gland progenitor cell control
Wang, X., Martinez, P. S., Terpstra, J. H., Shaalan, A., Proctor, G. B., Spijkervet, F. K. L., Vissink, A., Bootsma, H., Kroese, F. G. M., Coppes, R. P. & Pringle, S., 9-Nov-2021, In: Stem Cell Reports. 16, 11, p. 2813-2824 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Downloads (Pure) -
Epithelial-immune cell interplay in primary Sjogren syndrome salivary gland pathogenesis
Verstappen, G., Pringle, S., Bootsma, H. & Kroese, F. G. M., 28-Apr-2021, In: NATURE REVIEWS RHEUMATOLOGY. 16 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile3 Citations (Scopus)9 Downloads (Pure)
Activities
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Role of microenvironment on the regenerative potential of salivary gland stem cells
Rob Coppes (Supervisor), Sarah Pringle (Co-supervisor) & Arjan Vissink (Co-supervisor)
2018 → 2022Activity: Examination, teaching and supervision › Supervision and examination of PhD students of the UG › Academic
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Salivary gland stem cells age prematurely in primary Sjögren’s syndrome
Sarah Pringle (Speaker)
27-Sep-2018Activity: Talk and presentation › Professional or public presentation › Professional
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Senescence of salivary gland stem cells causes hyposalivation in primary Sjögren’s syndrome.
Sarah Pringle (Speaker)
18-Apr-2018Activity: Talk and presentation › Professional or public presentation › Professional
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Archives of Oral Biology (Journal)
Sarah Pringle (Peer reviewer)
2018Activity: Peer-review and editorial work › Peer-review › Professional
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PhD Supervision of project Paola Serrano Martinez
Sarah Pringle (Co-supervisor)
2018 → …Activity: Examination, teaching and supervision › Supervision and examination of PhD students of the UG › Academic
Press / Media
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ReumaNederland 2018 Jaaroverzicht
12/06/2019
1 Media contribution
Press/Media: Public Engagement Activities › Academic
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Gammele speekselklieren en uitgeputte stamcellen
06/11/2018
1 Media contribution
Press/Media: Research › Popular
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@SjogrensUMCG Twitter handle
01/06/2018
1 Media contribution
Press/Media: Public Engagement Activities › Academic
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International Society for Stem Cell Research Travel Grant
01/02/2011
1 Media contribution
Press/Media: Research › Popular
Prizes
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Article 9 Laboratory Animal Science license (CDP Groningen).
Pringle, Sarah (Recipient), 2010
Prize: Other distinction › Academic
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eBROK (awarded 2017, valid until 03/04/2021).
Pringle, Sarah (Recipient), 2017
Prize: Other distinction › Academic
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EULAR Abstract Award Basic Science
Verstappen, Gwenny (Recipient), Pringle, Sarah (Recipient), Gao, L. (Recipient), Liefers, Silvia (Recipient), van der Vegt, Bert (Recipient), Patel, V. (Recipient), Hu, S. (Recipient), Mukherjee, S. (Recipient), Vissink, Arjan (Recipient), Bootsma, Hendrika (Recipient) & Kroese, Frans (Recipient), 3-Jun-2020
Prize › Academic
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