Tjasso Blokzijl

2025

Chronic Allograft Enteropathy Treated with Vedolizumab: A Case Report

Trentadue, G., Kats-Ugurlu, G., Blokzijl, T., Haveman, J. W., Faber, K. N. & Dijkstra, G., Jan-2025, In: Transplantation Proceedings. 57, 1, p. 148-155 8 p.

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2024

Intraluminal oxygen can keep small bowel mucosa intact in a segmental ischemia model

Trentadue, G., Mensink, P. B. F., Kruse, C., Reszel, B., Kats-Ugurlu, G., Blokzijl, T., Haveman, J. W., Faber, K. N., Dijkstra, G., Hölscher, U. M., Kolkman, J. J. & Knichwitz, G., 14-Jun-2024, In: Scientific Reports. 14, 9 p., 13732.

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2023

Hydroxyurea attenuates hepatic stellate cell proliferation in vitro and liver fibrogenesis in vivo

Haijer, F., Koets-Shajari, S., Heegsma, J., Serna-Salas, S., Blokzijl, T., Buist-Homan, M., Moshage, H. & Faber, K. N., Sept-2023, In: The FASEB Journal. 37, 9, 14 p., e23124.

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Organoids as a model to study intestinal and liver dysfunction in severe malnutrition

Horcas-Nieto, J. M., Versloot, C. J., Langelaar-Makkinje, M., Gerding, A., Blokzijl, T., Koster, M. H., Baanstra, M., Martini, I. A., Coppes, R. P., Bourdon, C., van Ijzendoorn, S. C. D., Kim, P., Bandsma, R. H. J. & Bakker, B. M., Mar-2023, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1869, 3, 12 p., 166635.

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8 Citations (Scopus)

173 Downloads (Pure)

2022

HIF1α-Dependent Induction of TFRC by a Combination of Intestinal Inflammation and Systemic Iron Deficiency in Inflammatory Bowel Disease

Fagundes, R. R., Bourgonje, A. R., Hu, S., Barbieri, R., Jansen, B. H., Sinnema, N., Blokzijl, T., Taylor, C. T., Weersma, R. K., Faber, K. N. & Dijkstra, G., 8-Jun-2022, In: Frontiers in Physiology. 13, 16 p., 889091.

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10 Citations (Scopus)

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Mucosal Eosinophil Abundance in Non-Inflamed Colonic Tissue Is Associated with Response to Vedolizumab Induction Therapy in Inflammatory Bowel Disease

Gabriëls, R. Y., Bourgonje, A. R., von Martels, J. Z. H., Blokzijl, T., Weersma, R. K., Galinsky, K., Juarez, J., Faber, K. N., Kats-Ugurlu, G. & Dijkstra, G., 16-Jul-2022, In: Journal of Clinical Medicine. 11, 14, 18 p., 4141.

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5 Citations (Scopus)

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Regulation of the Intestinal Extra-Adrenal Steroidogenic Pathway Component LRH-1 by Glucocorticoids in Ulcerative Colitis

Landskron, G., Dubois-Camacho, K., Orellana-Serradell, O., De la Fuente, M., Parada-Venegas, D., Bitran, M., Diaz-Jimenez, D., Tang, S., Cidlowski, J. A., Li, X., Molina, H., Gonzalez, C. M., Simian, D., Lubascher, J., Pola, V., Montecino, M., Blokzijl, T., Faber, K. N., Gonzalez, M.-J. & Quera, R. & 1 others, Hermoso, M. A., 12-Jun-2022, In: Cells. 11, 12, 20 p., 1905.

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5 Citations (Scopus)

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2021

Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease

Hu, S., Uniken Venema, W. T., Westra, H.-J., Vich Vila, A., Barbieri, R., Voskuil, M. D., Blokzijl, T., Jansen, B. H., Li, Y., Daly, M. J., Xavier, R. J., Dijkstra, G., Festen, E. A. & Weersma, R. K., 18-Feb-2021, In: Nature Communications. 12, 1, 10 p., 1122.

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29 Citations (Scopus)

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Inulin-grown Faecalibacterium prausnitzii cross-feeds fructose to the human intestinal epithelium

Fagundes, R. R., Bourgonje, A. R., Saeed, A., Vich Vila, A., Plomp, N., Blokzijl, T., Sadaghian Sadabad, M., von Martels, J. Z. H., van Leeuwen, S. S., Weersma, R. K., Dijkstra, G., Harmsen, H. J. M. & Faber, K. N., 19-Nov-2021, In: Gut Microbes. 13, 1, 18 p., 1993582.

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24 Citations (Scopus)

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Isotype specific antibody responses to Mycobacterium Avium subspecies Paratuberculosis antigens are associated with the use of biological therapy in Inflammatory Bowel Disease

van der Sloot, K. W. J., Voskuil, M. D., Blokzijl, T., Dinkla, A., Ravesloot, L., Visschedijk, M. C., van Dullemen, H. M., Festen, E. A. M., Alizadeh, B. Z., van Leer-Buter, C., Weersma, R. K., van Goor, H., Koets, A. P. & Dijkstra, G., Aug-2021, In: Journal of Crohn's and Colitis. 15, 8, p. 1253-1263 11 p.

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9 Citations (Scopus)

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2020

Intestinal stenosis in Crohn's disease shows a generalized upregulation of genes involved in collagen metabolism and recognition that could serve as novel anti-fibrotic drug targets

van Haaften, W. T., Blokzijl, T., Hofker, H. S., Olinga, P., Dijkstra, G., Bank, R. A. & Boersema, M., Aug-2020, In: Therapeutic advances in gastroenterology. 13, 17 p.

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15 Citations (Scopus)

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Pirfenidone Inhibits Cell Proliferation and Collagen I Production of Primary Human Intestinal Fibroblasts

Cui, Y., Zhang, M., Leng, C., Blokzijl, T., Jansen, B. H., Dijkstra, G. & Faber, K. N., 22-Mar-2020, In: Cells. 9, 3, 16 p., 775.

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42 Citations (Scopus)

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Safe and Successful Treatment of Acute Cellular Rejection of an Intestine and Abdominal Wall Transplant With Vedolizumab

Trentadue, G., Kats-Ugurlu, G., Blokzijl, T., Diercks, G. F., Haveman, J. W., Faber, K. N. & Dijkstra, G., Feb-2020, In: Transplantation direct. 6, 2, 6 p., e527.

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20 Citations (Scopus)

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2019

A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease

Bourgonje, A. R., von Martels, J. Z. H., Gabriëls, R. Y., Blokzijl, T., Buist-Homan, M., Heegsma, J., Jansen, B. H., Dullemen, van, H. M., Festen, E. A. M., ter Steege, R. W. F., Visschedijk, M. C., Weersma, R. K., de Vos, P., Faber, K. N. & Dijkstra, G., 5-Nov-2019, In: Frontiers in Medicine. 6, p. 251 13 p., 251.

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47 Citations (Scopus)

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2018

Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn's Disease

Visschedijk, M. C., Spekhorst, L. M., Cheng, S.-C., van Loo, E. S., Jansen, B. H. D., Blokzijl, T., Kil, H., de Jong, D. J., Pierik, M., Maljaars, J. P. W. J., van der Woude, C. J., van Bodegraven, A. A., Oldenburg, B., Löwenberg, M., Nieuwenhuijs, V. B., Imhann, F., van Sommeren, S., Alberts, R., Xavier, R. J. & Dijkstra, G. & 4 others, Faber, K. N., Aldaz, C. M., Weersma, R. K. & Festen, E. A. M., May-2018, In: Journal of Crohn's and Colitis. 12, 5, p. 582-588 7 p.

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17 Citations (Scopus)

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Quantitative comparison of the neutralizing capacity, immunogenicity and cross-reactivity of anti-TNF-alpha biologicals and an Infliximab-biosimilar

Buurman, D. J., Blokzijl, T., Festen, E. A. M., Pham, B. T., Faber, K. N., Brouwer, E. & Dijkstra, G., 11-Dec-2018, In: PLoS ONE. 13, 12, 11 p., 0208922.

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8 Citations (Scopus)

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2016

HSPA6 is an ulcerative colitis susceptibility factor that is induced by cigarette smoke and protects intestinal epithelial cells by stabilizing anti-apoptotic Bcl-XL

Regeling, A., Imhann, F., Volders, H. H., Blokzijl, T., Bloks, V. W., Weersma, R. K., Dijkstra, G. & Faber, K. N., Apr-2016, In: Biochimica et biophysica acta-Molecular basis of disease. 1862, 4, p. 788-796 9 p.

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18 Citations (Scopus)

2015

A simple coculture system shows mutualism between anaerobic faecalibacteria and epithelial Caco-2 cells

Sadaghian, M., von Martels, J. Z. H., Khan, M., Blokzijl, T., Paglia, G., Dijkstra, G., Harmsen, H. J. M. & Faber, K. N., 15-Dec-2015, In: Scientific Reports. 5, 9 p., 17906.

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70 Citations (Scopus)

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The ATG16L1-T300A allele impairs clearance of pathosymbionts in the inflamed ileal mucosa of Crohn's disease patients

Sadabad, M. S., Regeling, A., de Goffau, M. C., Blokzijl, T., Weersma, R. K., Penders, J., Faber, K. N., Harmsen, H. J. M. & Dijkstra, G., Oct-2015, In: Gut. 64, 10, p. 1546-1552 7 p.

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78 Citations (Scopus)

2014

Histopathologic and molecular evaluation of the Organ Procurement and Transplantation Network selection criteria for intestinal graft donation

Roskott, A. M. C., van Haaften, W. T., Leuvenink, H. G. D., Ploeg, R. J., van Goor, H., Blokzijl, T., Ottens, P. J., Dijkstra, G. & Nieuwenhuijs, V. B., Jun-2014, In: Journal of Surgical Research. 189, 1, p. 143-151 9 p.

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11 Citations (Scopus)

Suppression of p21Rac signaling and increased innate immunity mediate remission in Crohn's disease

Parikh, K., Zhou, L., Somasundaram, R., Fuhler, G. M., Deuring, J. J., Blokzijl, T., Regeling, A., Kuipers, E. J., Weersma, R. K., Nuij, V. J., Alves, M., Vogelaar, L., Visser, L., de Haar, C., Krishnadath, K. K., van der Woude, C. J., Dijkstra, G., Faber, K. N. & Peppelenbosch, M. P., 23-Apr-2014, In: Science Translational Medicine. 6, 233, 12 p., 233ra53.

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25 Citations (Scopus)

2013

Westernized high-fat diet accelerates weight loss in dextran sulfate sodium-induced colitis in mice, which is further aggravated by supplementation of heme

van der Logt, E. M. J., Blokzijl, T., van der Meer, R., Faber, K. N. & Dijkstra, G., Jun-2013, In: Journal of Nutritional Biochemistry. 24, 6, p. 1159-1165 7 p.

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44 Citations (Scopus)

2012

Lithium induces intestinothrophic effects in the healthy colon, but does not ameliorate dextran sulfate sodium-induced colitis in mice

van der Logt, E. M. J., Blokzijl, T., Diepstra, A., Peppelenbosch, M. P., Huls, G., Faber, K. N. & Dijkstra, G., Feb-2012, In: e-SPEN Journal. 7, 1, p. e16-e22 7 p.

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1 Citation (Scopus)

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2009

Hodgkin Lymphoma Cell Lines Are Characterized by a Specific miRNA Expression Profile

Gibcus, J. H., Tan, L. P., Harms, G., Schakel, R. N., de Jong, D., Blokzijl, T., Moller, P., Poppema, S., Kroesen, B.-J. & van den Berg, A., Feb-2009, In: Neoplasia. 11, 2, p. 167-U86 14 p.

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126 Citations (Scopus)

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Specific expression of miR-17-5p and miR-127 in testicular and central nervous system diffuse large B-cell lymphoma

Robertus, J.-L., Harms, G., Blokzijl, T., Booman, M., de Jong, D., van Imhoff, G., Rosati, S., Schuuring, E., Kluin, P. & van den Berg, A., Apr-2009, In: Modern Pathology. 22, 4, p. 547-555 9 p.

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77 Citations (Scopus)

2008

miRNA analysis in B-cell chronic lymphocytic leukaemia: proliferation centres characterized by low miR-150 and high BIC/milk-155 expression

Wang, M., Tan, L. P., Dijkstra, M. K., van Lom, K., Robertus, J.-L., Harms, G., Blokzijl, T., Kooistra, K., van t'Veer, M. B., Rosati, S., Visser, L., Jongen-Lavrencic, M., Kluin, P. M. & van den Berg, A., May-2008, In: The Journal of Pathology. 215, 1, p. 13-20 8 p.

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104 Citations (Scopus)

The CD4+CD26-T-cell population in classical Hodgkin's lymphoma displays a distinctive regulatory T-cell profile

Ma, Y., Visser, L., Blokzijl, T., Harms, G., Atayar, C., Poppema, S. & van den Berg, A., May-2008, In: Laboratory Investigation. 88, 5, p. 482-490 9 p.

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56 Citations (Scopus)

2007

Global correlation of genome and transcriptome changes in classical Hodgkin lymphoma

Kluiver, J., Kok, K., Pfeil, I., de Jong, D., Blokzijl, T., Harms, G., van der Vlies, P., Diepstra, A., Atayar, C., Poppema, S., Kueppers, R. & van den Berg, A., Mar-2007, In: HEMATOLOGICAL ONCOLOGY. 25, 1, p. 21-29 9 p.

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23 Citations (Scopus)

Hodgkin's lymphoma associated T-cells exhibit a transcription factor profile consistent with distinct lymphoid compartments

Atayar, C., van den Berg, A., Blokzijl, T., Boot, M., Gascoyne, R. D., Visser, L. & Poppema, S., Oct-2007, In: Journal of Clinical Pathology. 60, 10, p. 1092-1097 6 p.

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17 Citations (Scopus)

Microarray amplification bias: loss of 30% differentially expressed genes due to long probe - poly(A)-tail distances

Boelens, M. C., te Meerman, G., Gibcus, J. H., Blokzijl, T., Boezen, H., Timens, W., Postma, D. S., Groen, H. & van den Berg, A., 15-Aug-2007, In: BMC Genomics. 8, 13 p., 277.

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16 Citations (Scopus)

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Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma

Kluiver, J., van den Berg, A., de Jong, D., Blokzijl, T., Harms, G., Bouwman, E., Jacobs, S., Poppema, S. & Kroesen, B.-J., 31-May-2007, In: Oncogene. 26, p. 3769-3776 8 p.

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129 Citations (Scopus)

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2006

BCL6 alternative breakpoint region break and homozygous deletion of 17q24 in the nodular lymphocyte predominance type of Hodgkin's lymphoma-derived cell line DEV

Atayar, C., Kok, K., Kluiver, J., Bosga - Bouwer, A., van den Berg, E., Van der Vlies, P., Blokzijl, T., Harms, G., Davelaar, I., Sikkema-raddatz, B., Martin-Subero, J. I., Siebert, R., Poppema, S. & van den Berg, A., Jun-2006, In: Human Pathology. 37, 6, p. 675-683 9 p.

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22 Citations (Scopus)

5 Downloads (Pure)

Gene expression analysis of dendritic/Langerhans cells and Langerhans cell histiocytosis

Rust, R., Kluiver, J., Visser, L., Harms, G., Blokzijl, T., Kamps, W. A., Poppema, S. & van den Berg, A., Aug-2006, In: The Journal of Pathology. 209, 4, p. 474-483 10 p.

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24 Citations (Scopus)

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Lack of BIC and MicroRNA miR-155 expression in primary cases of Burkitt lymphoma

Kluiver, J., Haralambieva, E., de Jong, D., Blokzijl, T., Jacobs, S., Kroesen, B.-J., Poppema, S. & van den Berg, A., Feb-2006, In: Genes Chromosomes & Cancer. 45, 2, p. 147-153 7 p.

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207 Citations (Scopus)

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2005

BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas

Kluiver, J., Poppema, S., de Jong, D., Blokzijl, T., Harms, G., Jacobs, S., Kroesen, B. & van den Berg, A., Oct-2005, In: The Journal of Pathology. 207, 2, p. 243-249 7 p.

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601 Citations (Scopus)

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Expression of the T-cell transcription factors, GATA-3 and T-bet, in the neoplastic cells of Hodgkin lymphomas

Atayar, C., Poppema, S., Blokzijl, T., Harms, G., Boot, M. & van den Berg, A., Jan-2005, In: American Journal of Pathology. 166, 1, p. 127-134 8 p.

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55 Citations (Scopus)

High expression of calcium-binding proteins, S100A10, S100A11 and CALM2 in anaplastic large cell lymphoma

Rust, R., Visser, L., van der Leij, J., Harms, G., Blokzijl, T., Deloulme, J., van der Vlies, P., Kamps, W., Kok, K., Lim, M., Poppema, S. & van den Berg, A., Dec-2005, In: British Journal of Haematology. 131, 5, p. 596-608 13 p.

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38 Citations (Scopus)

High expression of Mcl-1 in ALK positive and negative anaplastic large cell lymphoma

Rust, R., Harms, G., Blokzijl, T., Boot, M., Diepstra, A., Kluiver, J., Visser, L., Peh, S., Lim, M., Kamps, W., Poppema, S. & van den Berg, A., May-2005, In: Journal of Clinical Pathology. 58, 5, p. 520-524 5 p.

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19 Citations (Scopus)

TIMP-I expression in anaplastic large cell lymphoma is usually restricted to macrophages and only seldom observed in tumour cells

Rust, R., Blokzijl, T., Harms, G., Lim, M., Visser, L., Kamps, W., Poppema, S. & van den Berg, A., Aug-2005, In: The Journal of Pathology. 206, 4, p. 445-450 6 p.

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