Research output per year
Research output per year
Personal profile
Research interests
Fundamental and Applied Research, aimed at understanding molecular principles of metabolic health and mechanisms underlying the development of inborn and acquired metabolic diseases
- Cholesterol and Lipid Metabolism
- Bileacid Metabolism
- Microarray/RNAseq
- Statistics/Bioinformatics
Education/Academic qualification
HBO-B, Biochemie
Award Date: 1-Aug-1984
HBO_A, Klinische Chemie
Award Date: 1-Aug-1980
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases
Zhan, N., Wang, B., Martens, N., Liu, Y., Zhao, S., Voortman, G., van Rooij, J., Leijten, F., Vanmierlo, T., Kuipers, F., Jonker, J. W., Bloks, V. W., Lütjohann, D., Palumbo, M., Zimetti, F., Adorni, M. P., Liu, H. & Mulder, M. T., 9-Jan-2023, In: International Journal of Molecular Sciences. 24, 2, 23 p., 1290.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Downloads (Pure) -
Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia
Rutten, M. G. S., Lei, Y., Hoogerland, J. H., Bloks, V. W., Yang, H., Bos, T., Krishnamurthy, K. A., Bleeker, A., Koster, M. H., Thomas, R. E., Wolters, J. C., van den Bos, H., Mithieux, G., Rajas, F., Mardinoglu, A., Spierings, D. C. J., de Bruin, A., van de Sluis, B. & Oosterveer, M. H., 21-Apr-2023, In: Cancer & Metabolism. 11, 11 p., 5.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression
Verzijl, C. R. C., van de Peppel, I. P., Eilers, R. E., Bloks, V. W., Wolters, J. C., Koehorst, M., Kloosterhuis, N. J., Havinga, R., Jalving, M., Struik, D. & Jonker, J. W., Mar-2023, In: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 159, 10 p., 114270.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Downloads (Pure) -
Role of bile acid receptor FXR in development and function of brown adipose tissue
Yang, J., de Vries, H. D., Mayeuf-Louchart, A., Stroeve, J. H., Bloks, V. W., Koehorst, M., Duez, H., Staels, B., Kuipers, F. & van Zutphen, T., 2023, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 32 p., 159257.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)3 Downloads (Pure) -
DNA methylation trajectories and accelerated epigenetic aging in incident type 2 diabetes
Fraszczyk, E., Thio, C. H. L., Wackers, P., Dollé, M. E. T., Bloks, V. W., Hodemaekers, H., Picavet, H. S., Stynenbosch, M., Verschuren, W. M. M., Snieder, H., Spijkerman, A. M. W. & Luijten, M., Dec-2022, In: GeroScience. 44, p. 2671–2684 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure)
Datasets
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Dataset for: Male apoE*3-Leiden.CETP – mice on high-fat high-cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men.
Paalvast, Y. (Contributor), Gerding, A. (Contributor), Wang, Y. (Contributor), Bloks, V. (Contributor), van Dijk, T. (Contributor), Havinga, R. (Contributor), Willems van Dijk, K. (Contributor), Rensen, P. C. N. (Contributor), Bakker, B. (Contributor), Kuivenhoven, J. A. (Contributor) & Groen, B. (Contributor), University of Groningen, 16-Oct-2017
DOI: 10.6084/m9.figshare.5311096.v1
Dataset
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MOESM1 of The effects of bariatric surgery on clinical profile, DNA methylation, and ageing in severely obese patients
Buurman, W. A. (Contributor), Greve, J. W. (Contributor), Nicoletti, C. F. (Contributor), Wolffenbuttel, B. (Contributor), Luijten, M. (Contributor), Fraszczyk, E. (Contributor), Spijkerman, A. M. W. (Contributor), Bloks, V. (Contributor), Wackers, P. F. K. (Contributor), van Vliet-Ostaptchouk, J. (Contributor), Snieder, H. (Contributor), Crujeiras, A. B. (Contributor), Rensen, S. S. (Contributor) & Nonino, C. B. (Contributor), University of Groningen, 20-Jan-2020
DOI: 10.6084/m9.figshare.11664849.v1
Dataset