Research output per year
Research output per year
- 10 results
Search results
-
2024
Rebalancing the motor circuit restores movement in a Caenorhabditis elegans model for TDP-43 toxicity
Koopman, M., Güngördü, L., Janssen, L., Seinstra, R. I., Richmond, J. E., Okerlund, N., Wardenaar, R., Islam, P., Hogewerf, W., Brown, A. E. X., Jorgensen, E. M. & Nollen, E. A. A., 28-May-2024, In: Cell reports. 43, 5, 27 p., 114204.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile412 Downloads (Pure) -
2023
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain
Stroo, E., Janssen, L., Sin, O., Hogewerf, W., Koster, M., Harkema, L., Youssef, S. A., Beschorner, N., Wolters, A. H. G., Bakker, B., Becker, L., Garrett, L., Marschall, S., Hoelter, S. M., Wurst, W., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Thathiah, A. & Foijer, F. & 5 others, , Jul-2023, In: Life science alliance. 6, 7, 18 p., e202201730.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)71 Downloads (Pure) -
Neuronal overexpression of hTDP-43 in Caenorhabditis elegans mimics the cellular pathology commonly observed in TDP-43 proteinopathies.
Koopman, M., Güngördü, L., Seinstra, R. I., Hogewerf, W. & Nollen, E. A. A., 19-Apr-2023, In: microPublication biology. 2023, 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Downloads (Pure) -
2022
Alpha-Synuclein Lowering and Rescue of Motor Phenotype by miRNA-Based AAV Gene Therapy in In Vivo Parkinson's Disease Models
Broekmans, S. A., Tornero, C. V., Toonen, L., Valls, M., Erbrink, R., Ronde, K. E., Hogewerf, W., Tolsma, L. E. D., Seinstra, R. I., Janssen, L. L. S., Nollen, E. A. A. & Valles, A., Apr-2022, In: Molecular Therapy. 30, 4, p. 10-10 1 p.Research output: Contribution to journal › Meeting Abstract › Academic
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2021
Dose dependent lowering of alpha-synuclein and rescue of motor phenotype by miRNA-based AAV gene therapy
Broekmans, S. A., Tornero, C. V., Akyol, F., Toonen, L., Kieper, S., Ronde, K. E., Hogewerf, W., Tolsma, E. D., Seinstra, R. I., Janssen, L. L. S., Nolen, E. A. A. & Valles, A., Oct-2021, In: Human Gene Therapy. 32, 19-20, p. A51-A51 1 p.Research output: Contribution to journal › Meeting Abstract › Academic
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The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation
Pras, A., Houben, B., Aprile, F. A., Seinstra, R., Gallardo, R., Janssen, L., Hogewerf, W., Gallrein, C., De Vleeschouwer, M., Mata-Cabana, A., Koopman, M., Stroo, E., de Vries, M., Edwards, S. L., Kirstein, J., Vendruscolo, M., Falsone, S. F., Rousseau, F., Schymkowitz, J. & Nollen, E. A. A., 2-Nov-2021, In: The EMBO Journal. 40, 21, 18 p., e107568.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile15 Citations (Scopus)124 Downloads (Pure) -
2017
Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation
Sin, O., de Jong, T., Mata-Cabana, A., Kudron, M., Zaini, M. A., Aprile, F. A., Seinstra, R. I., Stroo, E., Prins, R. W., Martineau, C. N., Wang, H. H., Hogewerf, W., Steinhof, A., Wanker, E. E., Vendruscolo, M., Calkhoven, C. F., Reinke, V., Guryev, V. & Nollen, E. A. A., 16-Mar-2017, In: Molecular Cell. 65, 6, p. 1096-1108 19 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)310 Downloads (Pure) -
2012
High and Low LET Radiation Differentially Induce Normal Tissue Damage Signals
Niemantsverdriet, M., van Goethem, M.-J., Bron, R., Hogewerf, W., Brandenburg, S., Langendijk, J. A., van Luijk, P. & Coppes, R. P., 15-Jul-2012, In: International Journal of Radiation Oncology Biology Physics. 83, 4, p. 1291-1297 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile56 Citations (Scopus)68 Downloads (Pure) -
2011
High and low let radiation may differentially induce pulmonary toxicity signals
Niemantverdriet, M., van Goethem, M. J., Bron, R., Hogewert, W., Brandenburg, S., Langendijk, H., van Luijk, P. & Coppes, R., Mar-2011, p. S39-S39. 1 p.Research output: Contribution to conference › Poster › Academic
Open AccessFile36 Downloads (Pure) -
2009
Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet
Wiersma, H., Nijstad, N., de Boer, J. F., Out, R., Hogewerf, W., Van Berkel, T. J., Kuipers, F. & Tietge, U. J. F., Sept-2009, In: Atherosclerosis. 206, 1, p. 141-147 7 p.Research output: Contribution to journal › Article › Academic › peer-review
33 Citations (Scopus)