POC studies in TNFR2-humanized mice to support clinical development of ARTOS

Project Details


The overarching goal of the study is to confirm the therapeutic activity of the human ARTOS lead candidate in huTNFR2-k/i mice. These studies are necessary to support clinical development of ARTOS, in particular for CMC development and to plan the DRF and TOX study as well as the clinical dosing.
Effective start/end date01/01/202301/01/2025

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.