POC studies in TNFR2-humanized mice to support clinical development of ARTOS

Project Details


The overarching goal of the study is to confirm the therapeutic activity of the human ARTOS lead candidate in huTNFR2-k/i mice. These studies are necessary to support clinical development of ARTOS, in particular for CMC development and to plan the DRF and TOX study as well as the clinical dosing.
Effective start/end date01/01/202301/01/2025