This study is exploring new pathways that regulate cell size and shape, and how these pathways are affected in PKU. Cell size and shape are critical in the proper functioning of cells and particularly important in maintaining proper connections within the central nervous system. Many PKU patients suffer from a number of cognitive and behavioral challenges. Understanding the role of cell size and shape in the underlying cause of these cognitive and behavioral challenges may lead to the development of new therapeutics that will improve the lives of PKU patients.
|Effective start/end date||01/03/2019 → 01/05/2020|