The role of the microbiome in disease–associated mental and behavioral problems: The case of phenylketonuria (PKU)

2023

Phenylketonuria in a microbial world: Gut-microbiome-brain interactions shaping behavior in PKU

van der Goot, E., 2023, [Groningen]: University of Groningen. 225 p.

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2022

Gut-microbiome composition in response to phenylketonuria depends on dietary phenylalanine in BTBR Pah^enu2 mice

van der Goot, E., Vink, S. N., van Vliet, D., van Spronsen, F. J., Falcao Salles, J. & van der Zee, E. A., 4-Jan-2022, In: Frontiers in nutrition. 8, 16 p., 735366.

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8 Citations (Scopus)

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The increasing importance of LNAA supplementation in phenylketonuria at higher plasma phenylalanine concentrations

van Vliet, D., van der Goot, E., van Ginkel, W. G., van Faassen, H. J. R., de Blaauw, P., Kema, I. P., Heiner-Fokkema, M. R., van der Zee, E. A. & van Spronsen, F. J., Jan-2022, In: Molecular Genetics and Metabolism. 135, 1, p. 27-34 8 p.

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2021

Correlations of blood and brain biochemistry in phenylketonuria: Results from the Pah-enu2 PKU mouse

Dijkstra, A. M., van Vliet, N., van Vliet, D., Romani, C., Huijbregts, S. C. J., van der Goot, E., Hovens, I. B., van der Zee, E. A., Kema, I. P., Heiner-Fokkema, M. R. & van Spronsen, F. J., Nov-2021, In: Molecular Genetics and Metabolism. 134, 3, p. 250-256 7 p.

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9 Citations (Scopus)

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2020

A microbial community ecology perspective on the gut-microbiome-brain axis

van der Goot, E., van Spronsen, F. J., Falcão Salles, J. & van der Zee, E. A., 2-Sept-2020, In: Frontiers in endocrinology. 11, p. 611 611.

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6 Citations (Scopus)

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2019

Blood and brain biochemistry and behaviour in NTBC and dietary treated tyrosinemia type 1 mice

van Ginkel, W. G., van Vliet, D., van der Goot, E., Faassen, M. H. J. R., Vogel, A., Heiner-Fokkema, M. R., van der Zee, E. A. & van Spronsen, F. J., 16-Oct-2019, In: Nutrients. 11, 10, 13 p., 2486.

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Hippocampal microglia modifications in C57Bl/6 Pah^enu2 and BTBR Pah^enu2 phenylketonuria (PKU) mice depend on the genetic background, irrespective of disturbed sleep patterns

van der Goot, E., Bruinenberg, V. M., Hormann, F. M., Eisel, U. L. M., van Spronsen, F. J. & van der Zee, E. A., Apr-2019, In: Neurobiology of Learning and Memory. 160, p. 139-143 5 p.

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Long-term dietary intervention with low Phe and/or a specific nutrient combination improve certain aspects of brain functioning in phenylketonuria (PKU)

Bruinenberg, V. M., van Vliet, D., van der Goot, E., Counotte, D. S., Kuhn, M., van Spronsen, F. J. & van der Zee, E. A., 15-Mar-2019, In: PLoS ONE. 14, 3, 20 p., 0213391.

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8 Citations (Scopus)

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The benefit of large neutral amino acid supplementation to a liberalized phenylalanine-restricted diet in adult phenylketonuria patients: Evidence from adult Pah-Enu2 mice

van Vliet, D., van der Goot, E., van Ginkel, W. G., van Faassen, M. H. J. R., de Blaauw, P., Kema, I. P., Martinez, A., Heiner-Fokkema, M. R., van der Zee, E. A. & van Spronsen, F. J., Sept-2019, In: Nutrients. 11, 9, 14 p., 2252.

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11 Citations (Scopus)

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2018

Large neutral amino acid supplementation as an alternative to the phenylalanine-restricted diet in adults with phenylketonuria: Evidence from adult Pah-enu2 mice

van Vliet, D., van der Goot, E., Bruinenberg, V. M., van Faassen, M., de Blaauw, P., Kema, I. P., Heiner-Fokkema, M. R., van der Zee, E. A. & van Spronsen, F. J., Mar-2018, In: Journal of Nutritional Biochemistry. 53, p. 20-27 8 p.

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The role of the microbiome in disease–associated mental and behavioral problems: The case of phenylketonuria (PKU)

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