20 year evolution of Glyaderm® dermal regeneration matrix: the first non-commercial dermal regeneration matrix

Ali Pirayesh

doi:10.33612/diss.760333475

20 year evolution of Glyaderm® dermal regeneration matrix: the first non-commercial dermal regeneration matrix

Ali Pirayesh

Research output: Thesis › Thesis fully internal (DIV)

1265 Downloads (Pure)

Abstract

The research of Dr. Pirayesh encompassed a series of carefully planned studies ranging from laboratory research to clinical applications. The goal was to develop and validate Glyaderm® as an effective dermal replacement. Long-term studies have shown that Glyaderm® can be effectively integrated with autologous skin grafting after wound bed preparation, resulting in reduced costs and morbidity.

In a prospective, randomized clinical study, the effectiveness of Glyaderm® and autologous skin grafting was confirmed. This combination was found to be non-inferior to standard treatment in terms of graft uptake, scar scales and color. In addition, the two-stage procedure with Glyaderm® showed superior elasticity and better results in visual scar evaluation.

Glyaderm® has proven to be an effective choice for burn treatment, with beneficial outcomes and a positive impact on patients' quality of life.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Groningen
Supervisors/Advisors	van der Lei, Berend, Supervisor Monstrey, Stan, Supervisor, External person
Award date	13-Sept-2023
Place of Publication	[Groningen]
Publisher	University of Groningen
DOIs	https://doi.org/10.33612/diss.760333475
Publication status	Published - 2023

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10.33612/diss.760333475

Title and contentsFinal publisher's version, 765 KB
Chapter 1Final publisher's version, 1.26 MB
Chapter 2Final publisher's version, 1.63 MB
Chapter 3Final publisher's version, 2.18 MB
Chapter 4Final publisher's version, 2.19 MB
Chapter 5Final publisher's version, 1.54 MB
Chapter 6Final publisher's version, 1.36 MB
Chapter 7Final publisher's version, 1.5 MB
Chapter 8Final publisher's version, 1.89 MB
Chapter 9Final publisher's version, 2 MB
Chapter 10Final publisher's version, 3.21 MB
Chapter 11Final publisher's version, 2.57 MB
Chapter 12Final publisher's version, 1.42 MB
Chapter 13Final publisher's version, 2.11 MB
Complete thesisFinal publisher's version, 31.9 MB
PropositionsFinal publisher's version, 58.8 KB

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title = "20 year evolution of Glyaderm{\textregistered} dermal regeneration matrix: the first non-commercial dermal regeneration matrix",

abstract = "The research of Dr. Pirayesh encompassed a series of carefully planned studies ranging from laboratory research to clinical applications. The goal was to develop and validate Glyaderm{\textregistered} as an effective dermal replacement. Long-term studies have shown that Glyaderm{\textregistered} can be effectively integrated with autologous skin grafting after wound bed preparation, resulting in reduced costs and morbidity. In a prospective, randomized clinical study, the effectiveness of Glyaderm{\textregistered} and autologous skin grafting was confirmed. This combination was found to be non-inferior to standard treatment in terms of graft uptake, scar scales and color. In addition, the two-stage procedure with Glyaderm{\textregistered} showed superior elasticity and better results in visual scar evaluation. Glyaderm{\textregistered} has proven to be an effective choice for burn treatment, with beneficial outcomes and a positive impact on patients' quality of life.",

author = "Ali Pirayesh",

year = "2023",

doi = "10.33612/diss.760333475",

language = "English",

publisher = "University of Groningen",

school = "University of Groningen",

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TY - BOOK

T1 - 20 year evolution of Glyaderm® dermal regeneration matrix

T2 - the first non-commercial dermal regeneration matrix

AU - Pirayesh, Ali

PY - 2023

Y1 - 2023

N2 - The research of Dr. Pirayesh encompassed a series of carefully planned studies ranging from laboratory research to clinical applications. The goal was to develop and validate Glyaderm® as an effective dermal replacement. Long-term studies have shown that Glyaderm® can be effectively integrated with autologous skin grafting after wound bed preparation, resulting in reduced costs and morbidity. In a prospective, randomized clinical study, the effectiveness of Glyaderm® and autologous skin grafting was confirmed. This combination was found to be non-inferior to standard treatment in terms of graft uptake, scar scales and color. In addition, the two-stage procedure with Glyaderm® showed superior elasticity and better results in visual scar evaluation. Glyaderm® has proven to be an effective choice for burn treatment, with beneficial outcomes and a positive impact on patients' quality of life.

AB - The research of Dr. Pirayesh encompassed a series of carefully planned studies ranging from laboratory research to clinical applications. The goal was to develop and validate Glyaderm® as an effective dermal replacement. Long-term studies have shown that Glyaderm® can be effectively integrated with autologous skin grafting after wound bed preparation, resulting in reduced costs and morbidity. In a prospective, randomized clinical study, the effectiveness of Glyaderm® and autologous skin grafting was confirmed. This combination was found to be non-inferior to standard treatment in terms of graft uptake, scar scales and color. In addition, the two-stage procedure with Glyaderm® showed superior elasticity and better results in visual scar evaluation. Glyaderm® has proven to be an effective choice for burn treatment, with beneficial outcomes and a positive impact on patients' quality of life.

U2 - 10.33612/diss.760333475

DO - 10.33612/diss.760333475

M3 - Thesis fully internal (DIV)

PB - University of Groningen

CY - [Groningen]

ER -

20 year evolution of Glyaderm® dermal regeneration matrix: the first non-commercial dermal regeneration matrix

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