2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejectio

A. J. Demetris*, C. Bellamy, S. G. Hubscher, J. O'Leary, P. S. Randhawa, S. Feng, D. Neil, R. B. Colvin, G. McCaughan, J. J. Fung, A. Del Bello, F. P. Reinholt, H. Haga, O. Adeyi, A. J. Czaja, T. Schiano, M. I. Fiel, M. L. Smith, M. Sebagh, R. Y. TanigawaF. Yilmaz, G. Alexander, L. Baiocchi, M. Balasubramanian, I. Batal, A. K. Bhan, J. Bucuvalas, C. T. S. Cerski, F. Charlotte, M. E. de Vera, M. ElMonayeri, P. Fontes, E. E. Furth, A. S. H. Gouw, S. Hafezi-Bakhtiari, J. Hart, E. Honsova, W. Ismail, T. Itoh, N. C. Jhala, U. Khettry, G. B. Klintmalm, S. Knechtle, T. Koshiba, T. Kozlowski, C. R. Lassman, J. Lerut, J. Levitsky, L. Licini, R. Liotta, G. Mazariegos, M. I. Minervini, J. Misdraji, T. Mohanakumar, J. Molne, I. Nasser, J. Neuberger, M. O'Neil, O. Pappo, L. Petrovic, P. Ruiz, O. Sagol, A. Sanchez Fueyo, E. Sasatomi, A. Shaked, M. Shiller, T. Shimizu, B. Sis, A. Sonzogni, H. L. Stevenson, S. N. Thung, G. Tisone, A. C. Tsamandas, A. Wernerson, T. Wu, A. Zeevi, Y. Zen

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review

209 Citations (Scopus)

Abstract

The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France, June 5-10, 2011), 12th (Comandatuba, Brazil, August 19-23, 2013), and 13th (Vancouver, British Columbia, Canada, October 5-10, 2015) meetings of the Banff Conference on Allograft Pathology. Discussion continued online. The primary goal was to introduce guidelines and consensus criteria for the diagnosis of liver allograft antibody-mediated rejection and provide a comprehensive update of all Banff Schema recommendations. Included are new recommendations for complement component 4d tissue staining and interpretation, staging liver allograft fibrosis, and findings related to immunosuppression minimization. In an effort to create a single reference document, previous unchanged criteria are also included.

Original languageEnglish
Pages (from-to)2816-2835
Number of pages20
JournalAmerican Journal of Transplantation
Volume16
Issue number10
DOIs
Publication statusPublished - Oct-2016

Keywords

  • NOVO AUTOIMMUNE HEPATITIS
  • DONOR-SPECIFIC ANTIBODIES
  • ACUTE CELLULAR REJECTION
  • HUMAN-LEUKOCYTE ANTIGEN
  • ACUTE HUMORAL REJECTION
  • HISTOCOMPATIBILITY COMPLEX ANTIGENS
  • IDIOPATHIC PORTAL-HYPERTENSION
  • DIFFERENT STAINING TECHNIQUES
  • LYMPHOCYTOTOXIC CROSS-MATCH
  • NORMAL HUMAN ORGANS

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