6-chromanol derivatives for use as a medicament

Robert Henk Henning (Inventor), Gerrit Jan Willem Euverink (Inventor), Guido Krenning (Inventor), Adrianus Cornelis van der Graaf (Inventor)

Research output: Patent

Abstract

he present invention relates to the (S) enantiomeric form of certain 6-chromanol derivatives for use as a medicament. Especially, the present invention relates to the (S) enantiomeric form of a 6-chromanol derivative for use as a medicament wherein said 6-chromanol derivative is chosen from the group consisting of (6-hydroxy-2,5,7,8-tetramethylchroman-2- yl)(piperazin-1-yl)methanone; N-(benzyl)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamide; N-(phenyl)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamide; methyl 4-(6-hydroxy-2,5,7,8- tetramethylchroman-2-carboxamido)benzoate; (6-hydroxy-2,5,7,8-tetramethylchroman-2- yl)(morpholino)methanone, and pharmaceutically acceptable salts or bases thereof and pharmaceutically acceptable salts thereof.
Original languageEnglish
Patent numberWO201938360
Priority date25/08/2017
Filing date23/08/2018
Publication statusPublished - 28-Feb-2019

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