Abstract
If patients being treated with anticoagulants need to undergo an operation then physicians need to consider whether to suspend the use of this medication or to allow its use to be continued. Suspending the use of anticoagulants increases the risk of thrombosis, whereas continued use may cause bleeding complications. No evidence-based scientific research has been carried out regarding best practice for the perioperative use of anticoagulants.Antithrombotic drugs are vitamin K antagonists and platelet aggregation inhibitors. For daily practice, appropriate bridging strategies can be used for perioperative anticoagulant policy for various risk groups, such as patients with venous thromboembolism, atrial fibrillations, mechanical heart valves and coronary heart diseases (including coronary stents) and patients who have experienced a cerebrovascular accident. In the vast majority of cases the treating physician must carefully consider each individual case in order to realise the best policy.
Translated title of the contribution | Perioperative interruption of anticoagulants: Practical recommendations |
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Original language | Dutch |
Pages (from-to) | 1622-1628 |
Number of pages | 7 |
Journal | Nederlands Tijdschrift voor Geneeskunde |
Volume | 153 |
Issue number | 33 |
Publication status | Published - 15-Aug-2009 |
Keywords
- acenocoumarol
- acetylsalicylic acid
- anticoagulant agent
- antithrombocytic agent
- antivitamin K
- clopidogrel
- desmopressin diacetate
- dipyridamole
- heparin
- low molecular weight heparin
- phenprocoumon
- thienopyridine derivative
- warfarin
- article
- clinical trial
- controlled clinical trial
- controlled study
- coronary stent
- deep vein thrombosis
- drug contraindication
- heart atrium fibrillation
- heart valve prosthesis
- hemostasis
- human
- perioperative period
- postoperative hemorrhage
- prospective study
- randomized controlled trial
- risk factor
- thrombocyte aggregation
- thrombosis
- transluminal coronary angioplasty
- venous thromboembolism