A COMPARISON OF INTERNAL MAMMARY ARTERY AND SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-SURGERY - NO DIFFERENCE IN 1-YEAR OCCLUSION RATES AND CLINICAL OUTCOME

J VANDERMEER; HL HILLEGE; WH VANGILST; AB DELARIVIERE; PHJM DUNSELMAN; [No Value] FIDLER; GJ KOOTSTRA; BJM MULDER; M PFISTERER; KI LIE; FL MEIJLER; CAPL ASCOOP; AJ DUNNING; HR MICHELS; EOR DEMEDINA; HJJ WELLENS; AC ARNTZENIUS; J LUBSEN; RM SCHUILENBERG; SH SKOTNICKI; PJ DEFEYTER; JCA HOORNTJE; FC VISSER; RB VANDIJK; P DENHEYER; J JANSSEN; GVA VANOMMEN; FWHM BAR; RNW HAUER; JW VIERSMA; D FANGGIDAEJ; AL LIEM; JHM TEUBEN; HF VANDERVEEN; JGP TIJSSEN; M VUIJK; MJL DEJONGSTE; A EIJGELAAR; R VANDERDOEF; J PIEK; NG MEYNE; RMTY GIN; FE VERMEULEN; P BUSER; F BURKART; E GRADEL; JJRM BONNIER; JH BAVINCK; J NUSE; K SEGGEWISS; H POSIVAL; U GLEICHMANN; R KORFER; W TERRES; W BLEIFELD; P KALMAR; OEK PENN; JF HITCHCOCK; E. Wever

A COMPARISON OF INTERNAL MAMMARY ARTERY AND SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-SURGERY - NO DIFFERENCE IN 1-YEAR OCCLUSION RATES AND CLINICAL OUTCOME

J VANDERMEER^*
, HL HILLEGE
, WH VANGILST
, AB DELARIVIERE
, PHJM DUNSELMAN
, [No Value] FIDLER
, GJ KOOTSTRA
, BJM MULDER
, M PFISTERER
, KI LIE
, FL MEIJLER
, CAPL ASCOOP
, AJ DUNNING
, HR MICHELS
, EOR DEMEDINA
, HJJ WELLENS
, AC ARNTZENIUS
, J LUBSEN
, RM SCHUILENBERG
, SH SKOTNICKI

PJ DEFEYTER, JCA HOORNTJE, FC VISSER, RB VANDIJK, P DENHEYER, J JANSSEN, GVA VANOMMEN, FWHM BAR, RNW HAUER, JW VIERSMA, D FANGGIDAEJ, AL LIEM, JHM TEUBEN, HF VANDERVEEN, JGP TIJSSEN, M VUIJK, MJL DEJONGSTE, A EIJGELAAR, R VANDERDOEF, J PIEK, NG MEYNE, RMTY GIN, FE VERMEULEN, P BUSER, F BURKART, E GRADEL, JJRM BONNIER, JH BAVINCK, J NUSE, K SEGGEWISS, H POSIVAL, U GLEICHMANN, R KORFER, W TERRES, W BLEIFELD, P KALMAR, OEK PENN, JF HITCHCOCK, E. Wever

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

42 Citations (Scopus)

Abstract

Background Superior patency rates for internal mammary artery (IMA) grafts compared with vein coronary bypass grafts have been demonstrated by retrospective studies. This difference may have been affected by selection bias of patients and coronary arteries for IMA grafting.

Methods and Results To estimate the difference between IMA and vein grafts, we analyzed graft patency data of 912 patients who entered a randomized clinical drug trial. In this trial, 494 patients received both IMA and vein grafts (group 1) and 418 only vein grafts (group 2). Occlusion rates of IMA grafts and IMA plus vein grafts in group 1 were compared with those of vein grafts in group 2. Multivariate analysis was used to compare occlusion rates of IMA and vein grafts while other variables related to graft patency were controlled for. In addition, 1-year clinical outcome was assessed by the incidence of myocardial infarction, thrombosis, major bleeding, and death. Occlusion rates of distal anastomoses in group 1 versus group 2 were 5.4% (IMA grafts) versus 12.7% (vein grafts) (P

Conclusions The observed difference in 1-year occlusion rates between IMA and vein grafts can be explained by a maldistribution of graft characteristics by selection of coronary arteries for IMA grafting rather than being ascribed to graft material. One-year clinical outcome is not improved by IMA grafting.

Original language	English
Pages (from-to)	2367-2374
Number of pages	8
Journal	Circulation
Volume	90
Issue number	5
Publication status	Published - Nov-1994

Keywords

ARTERIES
VEINS
BYPASS
CLINICAL TRIALS
LOW-DOSE ASPIRIN
ORAL ANTICOAGULANTS
PATENCY
SURVIVAL
DIPYRIDAMOLE
CHOICE
TRIAL

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VANDERMEER, J., HILLEGE, HL., VANGILST, WH., DELARIVIERE, AB., DUNSELMAN, PHJM., FIDLER, N. V., KOOTSTRA, GJ., MULDER, BJM., PFISTERER, M., LIE, KI., MEIJLER, FL., ASCOOP, CAPL., DUNNING, AJ., MICHELS, HR., DEMEDINA, EOR., WELLENS, HJJ., ARNTZENIUS, AC., LUBSEN, J., SCHUILENBERG, RM., ... Wever, E. (1994). A COMPARISON OF INTERNAL MAMMARY ARTERY AND SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-SURGERY - NO DIFFERENCE IN 1-YEAR OCCLUSION RATES AND CLINICAL OUTCOME. Circulation, 90(5), 2367-2374.

@article{8ad7417edee043258118aee6acd78eed,

title = "A COMPARISON OF INTERNAL MAMMARY ARTERY AND SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-SURGERY - NO DIFFERENCE IN 1-YEAR OCCLUSION RATES AND CLINICAL OUTCOME",

abstract = "Background Superior patency rates for internal mammary artery (IMA) grafts compared with vein coronary bypass grafts have been demonstrated by retrospective studies. This difference may have been affected by selection bias of patients and coronary arteries for IMA grafting.Methods and Results To estimate the difference between IMA and vein grafts, we analyzed graft patency data of 912 patients who entered a randomized clinical drug trial. In this trial, 494 patients received both IMA and vein grafts (group 1) and 418 only vein grafts (group 2). Occlusion rates of IMA grafts and IMA plus vein grafts in group 1 were compared with those of vein grafts in group 2. Multivariate analysis was used to compare occlusion rates of IMA and vein grafts while other variables related to graft patency were controlled for. In addition, 1-year clinical outcome was assessed by the incidence of myocardial infarction, thrombosis, major bleeding, and death. Occlusion rates of distal anastomoses in group 1 versus group 2 were 5.4\% (IMA grafts) versus 12.7\% (vein grafts) (PConclusions The observed difference in 1-year occlusion rates between IMA and vein grafts can be explained by a maldistribution of graft characteristics by selection of coronary arteries for IMA grafting rather than being ascribed to graft material. One-year clinical outcome is not improved by IMA grafting.",

keywords = "ARTERIES, VEINS, BYPASS, CLINICAL TRIALS, LOW-DOSE ASPIRIN, ORAL ANTICOAGULANTS, PATENCY, SURVIVAL, DIPYRIDAMOLE, CHOICE, TRIAL",

author = "J VANDERMEER and HL HILLEGE and WH VANGILST and AB DELARIVIERE and PHJM DUNSELMAN and FIDLER, \{[No Value]\} and GJ KOOTSTRA and BJM MULDER and M PFISTERER and KI LIE and FL MEIJLER and CAPL ASCOOP and AJ DUNNING and HR MICHELS and EOR DEMEDINA and HJJ WELLENS and AC ARNTZENIUS and J LUBSEN and RM SCHUILENBERG and SH SKOTNICKI and PJ DEFEYTER and JCA HOORNTJE and FC VISSER and RB VANDIJK and P DENHEYER and J JANSSEN and GVA VANOMMEN and FWHM BAR and RNW HAUER and JW VIERSMA and D FANGGIDAEJ and AL LIEM and JHM TEUBEN and HF VANDERVEEN and JGP TIJSSEN and M VUIJK and MJL DEJONGSTE and A EIJGELAAR and R VANDERDOEF and J PIEK and NG MEYNE and RMTY GIN and FE VERMEULEN and P BUSER and F BURKART and E GRADEL and JJRM BONNIER and JH BAVINCK and J NUSE and K SEGGEWISS and H POSIVAL and U GLEICHMANN and R KORFER and W TERRES and W BLEIFELD and P KALMAR and OEK PENN and JF HITCHCOCK and E. Wever",

year = "1994",

month = nov,

language = "English",

volume = "90",

pages = "2367--2374",

journal = "Circulation",

issn = "0009-7322",

publisher = "Lippincott Williams and Wilkins",

number = "5",

}

VANDERMEER, J, HILLEGE, HL , VANGILST, WH, DELARIVIERE, AB, DUNSELMAN, PHJM, FIDLER, NV, KOOTSTRA, GJ, MULDER, BJM, PFISTERER, M, LIE, KI, MEIJLER, FL, ASCOOP, CAPL, DUNNING, AJ, MICHELS, HR, DEMEDINA, EOR, WELLENS, HJJ, ARNTZENIUS, AC, LUBSEN, J, SCHUILENBERG, RM, SKOTNICKI, SH, DEFEYTER, PJ, HOORNTJE, JCA, VISSER, FC, VANDIJK, RB, DENHEYER, P, JANSSEN, J, VANOMMEN, GVA, BAR, FWHM, HAUER, RNW, VIERSMA, JW, FANGGIDAEJ, D, LIEM, AL, TEUBEN, JHM, VANDERVEEN, HF, TIJSSEN, JGP, VUIJK, M, DEJONGSTE, MJL, EIJGELAAR, A, VANDERDOEF, R, PIEK, J, MEYNE, NG, GIN, RMTY, VERMEULEN, FE, BUSER, P, BURKART, F, GRADEL, E, BONNIER, JJRM, BAVINCK, JH, NUSE, J, SEGGEWISS, K, POSIVAL, H, GLEICHMANN, U, KORFER, R, TERRES, W, BLEIFELD, W, KALMAR, P, PENN, OEK, HITCHCOCK, JF & Wever, E 1994, 'A COMPARISON OF INTERNAL MAMMARY ARTERY AND SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-SURGERY - NO DIFFERENCE IN 1-YEAR OCCLUSION RATES AND CLINICAL OUTCOME', Circulation, vol. 90, no. 5, pp. 2367-2374.

TY - JOUR

T1 - A COMPARISON OF INTERNAL MAMMARY ARTERY AND SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-SURGERY - NO DIFFERENCE IN 1-YEAR OCCLUSION RATES AND CLINICAL OUTCOME

AU - VANDERMEER, J

AU - HILLEGE, HL

AU - VANGILST, WH

AU - DELARIVIERE, AB

AU - DUNSELMAN, PHJM

AU - FIDLER, [No Value]

AU - KOOTSTRA, GJ

AU - MULDER, BJM

AU - PFISTERER, M

AU - LIE, KI

AU - MEIJLER, FL

AU - ASCOOP, CAPL

AU - DUNNING, AJ

AU - MICHELS, HR

AU - DEMEDINA, EOR

AU - WELLENS, HJJ

AU - ARNTZENIUS, AC

AU - LUBSEN, J

AU - SCHUILENBERG, RM

AU - SKOTNICKI, SH

AU - DEFEYTER, PJ

AU - HOORNTJE, JCA

AU - VISSER, FC

AU - VANDIJK, RB

AU - DENHEYER, P

AU - JANSSEN, J

AU - VANOMMEN, GVA

AU - BAR, FWHM

AU - HAUER, RNW

AU - VIERSMA, JW

AU - FANGGIDAEJ, D

AU - LIEM, AL

AU - TEUBEN, JHM

AU - VANDERVEEN, HF

AU - TIJSSEN, JGP

AU - VUIJK, M

AU - DEJONGSTE, MJL

AU - EIJGELAAR, A

AU - VANDERDOEF, R

AU - PIEK, J

AU - MEYNE, NG

AU - GIN, RMTY

AU - VERMEULEN, FE

AU - BUSER, P

AU - BURKART, F

AU - GRADEL, E

AU - BONNIER, JJRM

AU - BAVINCK, JH

AU - NUSE, J

AU - SEGGEWISS, K

AU - POSIVAL, H

AU - GLEICHMANN, U

AU - KORFER, R

AU - TERRES, W

AU - BLEIFELD, W

AU - KALMAR, P

AU - PENN, OEK

AU - HITCHCOCK, JF

AU - Wever, E.

PY - 1994/11

Y1 - 1994/11

N2 - Background Superior patency rates for internal mammary artery (IMA) grafts compared with vein coronary bypass grafts have been demonstrated by retrospective studies. This difference may have been affected by selection bias of patients and coronary arteries for IMA grafting.Methods and Results To estimate the difference between IMA and vein grafts, we analyzed graft patency data of 912 patients who entered a randomized clinical drug trial. In this trial, 494 patients received both IMA and vein grafts (group 1) and 418 only vein grafts (group 2). Occlusion rates of IMA grafts and IMA plus vein grafts in group 1 were compared with those of vein grafts in group 2. Multivariate analysis was used to compare occlusion rates of IMA and vein grafts while other variables related to graft patency were controlled for. In addition, 1-year clinical outcome was assessed by the incidence of myocardial infarction, thrombosis, major bleeding, and death. Occlusion rates of distal anastomoses in group 1 versus group 2 were 5.4% (IMA grafts) versus 12.7% (vein grafts) (PConclusions The observed difference in 1-year occlusion rates between IMA and vein grafts can be explained by a maldistribution of graft characteristics by selection of coronary arteries for IMA grafting rather than being ascribed to graft material. One-year clinical outcome is not improved by IMA grafting.

AB - Background Superior patency rates for internal mammary artery (IMA) grafts compared with vein coronary bypass grafts have been demonstrated by retrospective studies. This difference may have been affected by selection bias of patients and coronary arteries for IMA grafting.Methods and Results To estimate the difference between IMA and vein grafts, we analyzed graft patency data of 912 patients who entered a randomized clinical drug trial. In this trial, 494 patients received both IMA and vein grafts (group 1) and 418 only vein grafts (group 2). Occlusion rates of IMA grafts and IMA plus vein grafts in group 1 were compared with those of vein grafts in group 2. Multivariate analysis was used to compare occlusion rates of IMA and vein grafts while other variables related to graft patency were controlled for. In addition, 1-year clinical outcome was assessed by the incidence of myocardial infarction, thrombosis, major bleeding, and death. Occlusion rates of distal anastomoses in group 1 versus group 2 were 5.4% (IMA grafts) versus 12.7% (vein grafts) (PConclusions The observed difference in 1-year occlusion rates between IMA and vein grafts can be explained by a maldistribution of graft characteristics by selection of coronary arteries for IMA grafting rather than being ascribed to graft material. One-year clinical outcome is not improved by IMA grafting.

KW - ARTERIES

KW - VEINS

KW - BYPASS

KW - CLINICAL TRIALS

KW - LOW-DOSE ASPIRIN

KW - ORAL ANTICOAGULANTS

KW - PATENCY

KW - SURVIVAL

KW - DIPYRIDAMOLE

KW - CHOICE

KW - TRIAL

M3 - Article

SN - 0009-7322

VL - 90

SP - 2367

EP - 2374

JO - Circulation

JF - Circulation

IS - 5

ER -

A COMPARISON OF INTERNAL MAMMARY ARTERY AND SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-SURGERY - NO DIFFERENCE IN 1-YEAR OCCLUSION RATES AND CLINICAL OUTCOME

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