A new CT-based method to quantify radiation-induced lung damage in patients

Ghazaleh Ghobadi, Erwin M. Wiegman, Johannes A. Langendijk, Joachim Widder, Robert P. Coppes, Peter van Luijk*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

29 Citations (Scopus)
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Abstract

A new method to assess radiation-induced lung toxicity (RILT) using CT-scans was developed. It is more sensitive in detecting damage and corresponds better to physician-rated radiation pneumonitis than routinely-used methods. Use of this method may improve lung toxicity assessment and thereby facilitate development of more accurate predictive models for RILT. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)4-8
Number of pages5
JournalRadiotherapy and Oncology
Volume117
Issue number1
DOIs
Publication statusPublished - Oct-2015

Keywords

  • Radiation pneumonitis
  • Lung toxicity
  • Radiotherapy
  • Computed tomography
  • PULMONARY-FUNCTION
  • DENSITY CHANGES
  • RAT LUNG
  • COMPUTED-TOMOGRAPHY
  • BREAST-CANCER
  • END-POINTS
  • IRRADIATION
  • INJURY
  • PNEUMONITIS
  • THERAPY

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