A niobium water target for routine production of [F-18]Fluoride with a MC 17 cyclotron

J. Siikanen; T. Ohlsson; J. Medema; J. Van-Essen; A. Sandell

doi:10.1016/j.apradiso.2012.10.011

A niobium water target for routine production of [F-18]Fluoride with a MC 17 cyclotron

J. Siikanen^*, T. Ohlsson, J. Medema, J. Van-Essen, A. Sandell

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Scopus)

Abstract

A [F-18]Fluoride water target was constructed for a Scanditronix MC 17 cyclotron, without a beam line, with a typical wide beam of similar to 30 x 5 mm(2). Niobium was used as target chamber material. One hour irradiation with 45 mu A protons yields about 110 GBq [F-18] Fluoride. The saturation yield is 8.0 +/- 0.6 GBq/mu A (EOB). The FDG yield is 60 +/- 5% (EIS) with a TracerLab MX (G.E. Healthcare). More than 100 GBq FOG is routinely produced after a 2 h irradiation. (C) 2012 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	133-136
Number of pages	4
Journal	Applied Radiation and Isotopes
Volume	73
DOIs	https://doi.org/10.1016/j.apradiso.2012.10.011
Publication status	Published - Feb-2013

Keywords

Water target
FDG
Niobium
[18F]Fluoride

Access to Document

10.1016/j.apradiso.2012.10.011

Handle.net

Persistent link

Cite this

@article{f250411b4ba148f79c6c97ff9153242a,

title = "A niobium water target for routine production of [F-18]Fluoride with a MC 17 cyclotron",

abstract = "A [F-18]Fluoride water target was constructed for a Scanditronix MC 17 cyclotron, without a beam line, with a typical wide beam of similar to 30 x 5 mm(2). Niobium was used as target chamber material. One hour irradiation with 45 mu A protons yields about 110 GBq [F-18] Fluoride. The saturation yield is 8.0 +/- 0.6 GBq/mu A (EOB). The FDG yield is 60 +/- 5% (EIS) with a TracerLab MX (G.E. Healthcare). More than 100 GBq FOG is routinely produced after a 2 h irradiation. (C) 2012 Elsevier Ltd. All rights reserved.",

keywords = "Water target, FDG, Niobium, [18F]Fluoride",

author = "J. Siikanen and T. Ohlsson and J. Medema and J. Van-Essen and A. Sandell",

year = "2013",

month = feb,

doi = "10.1016/j.apradiso.2012.10.011",

language = "English",

volume = "73",

pages = "133--136",

journal = "Applied Radiation and Isotopes",

issn = "0969-8043",

publisher = "PERGAMON-ELSEVIER SCIENCE LTD",

}

TY - JOUR

T1 - A niobium water target for routine production of [F-18]Fluoride with a MC 17 cyclotron

AU - Siikanen, J.

AU - Ohlsson, T.

AU - Medema, J.

AU - Van-Essen, J.

AU - Sandell, A.

PY - 2013/2

Y1 - 2013/2

N2 - A [F-18]Fluoride water target was constructed for a Scanditronix MC 17 cyclotron, without a beam line, with a typical wide beam of similar to 30 x 5 mm(2). Niobium was used as target chamber material. One hour irradiation with 45 mu A protons yields about 110 GBq [F-18] Fluoride. The saturation yield is 8.0 +/- 0.6 GBq/mu A (EOB). The FDG yield is 60 +/- 5% (EIS) with a TracerLab MX (G.E. Healthcare). More than 100 GBq FOG is routinely produced after a 2 h irradiation. (C) 2012 Elsevier Ltd. All rights reserved.

AB - A [F-18]Fluoride water target was constructed for a Scanditronix MC 17 cyclotron, without a beam line, with a typical wide beam of similar to 30 x 5 mm(2). Niobium was used as target chamber material. One hour irradiation with 45 mu A protons yields about 110 GBq [F-18] Fluoride. The saturation yield is 8.0 +/- 0.6 GBq/mu A (EOB). The FDG yield is 60 +/- 5% (EIS) with a TracerLab MX (G.E. Healthcare). More than 100 GBq FOG is routinely produced after a 2 h irradiation. (C) 2012 Elsevier Ltd. All rights reserved.

KW - Water target

KW - FDG

KW - Niobium

KW - [18F]Fluoride

U2 - 10.1016/j.apradiso.2012.10.011

DO - 10.1016/j.apradiso.2012.10.011

M3 - Article

SN - 0969-8043

VL - 73

SP - 133

EP - 136

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

ER -